Distribution of animal-level prevalence of paramphistomes in batches of cattle at slaughter by age group and observation period.

<p>Animal-level prevalence is shown in categories, where by the first value of the range is excluded and the last value is included. Negative batches are shown as a separate category at animal-level prevalence of zero.</p

Animal-level prevalence for cattle slaughtered in New Caledonia in 2013.

<p>Animal-level prevalence for cattle slaughtered in New Caledonia in 2013.</p

Geographical distribution of inspected cattle and deer herds in New Caledonia.

<p>Pie charts indicate the inter-herd prevalence of paramphistomes in cattle for each municipality, where the size of the pie chart is proportional to the number of herds inspected from that municipality. Stars indicate municipalities with deer and colour indicates whether or not paramphistomes were observed in deer from that municipality.</p

Binomial general linear mixed model animal-level data output (i).

<p>Binomial general linear mixed model animal-level data output (i).</p

Binomial general linear mixed model rumen fluke-level data output (i).

<p>Binomial general linear mixed model rumen fluke-level data output (i).</p

Phylogenetic tree showing the topological relationship between mtDNA rRNA-Thr/Cox1 fragments of <i>Calicophoron calicophorum</i> from cattle (white dots, C) and deer (black dots, D) using <i>Calicophoron daubneyi</i> as outgroup.

<p>Numbers along branches indicate bootstrap support (values over 50 shown). Where available, data on region of origin is included (N = North; NE = North-East; E = East; SW = South West; W = West; NW = North West).</p

Batch-level prevalence for cattle slaughtered in New Caledonia in 2013.

<p>Batch-level prevalence for cattle slaughtered in New Caledonia in 2013.</p

Additional file 1: of Psychosocial and behavioral impact of breast cancer risk assessed by testing for common risk variants: protocol of a prospective study

Study Questionnaires. This file contains all the study's questionnaires including baseline, short term, and long term questionnaire for receivers and decliners. (PDF 1051 kb

Summary of germline <i>RAD51D</i> variants.

a<p>Exon (Ex), intervening sequence (IVS).</p>b<p>Variant positions are reported in reference to NCBI RefSeq NM_002878.3 (mRNA) and NP_002869 (protein).</p>c<p>In addition to the variants listed, common variants rs4796033, rs28363284 (non-synonymous) and rs9901455 (synonymous) were detected at high frequency in both cases and controls.</p>d<p>All variants were queried against 1000 Genomes (1000 G) data using the 1000 Genomes Browser which integrates SNP and indel calls from 1,092 individuals (data release 20110521 v3). The minor allele frequency (MAF) is provided here.</p>e<p>All variants were queried against Exome Variant Server (EVS), NHLBI Exome Sequencing Project (ESP). EVS contains SNP information from 5,379 individuals (data release ESP5400). The minor allele frequency (MAF) is provided here.</p>f<p>Breast cancer only family (BC), ovarian cancer only family (OC), breast and ovarian cancer family (BC/OC).</p>g<p>Variants annotated with N/A were not assessed in control samples.</p>h<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054772#pone.0054772-Grantham1" target="_blank">[22]</a>.</p

Loss of heterozygosity analysis of the c.556C>T (p.(Arg186*)) variant.

<p>Sequencing (forward and reverse) of the heterozygous c.556C>T variant in the germline sample, and tumour DNA showing loss of the wildtype allele (with some contamination from normal DNA).</p