547 research outputs found
A Parallel Monte-Carlo Tree Search-Based Metaheuristic For Optimal Fleet Composition Considering Vehicle Routing Using Branch & Bound
In this paper, a Monte-Carlo Tree Search (MCTS)-based metaheuristic is
developed that guides a Branch & Bound (B&B) algorithm to find the globally
optimal solution to the heterogeneous fleet composition problem while
considering vehicle routing. Fleet Size and Mix Vehicle Routing Problem with
Time Windows (FSMVRPTW). The metaheuristic and exact algorithms are implemented
in a parallel hybrid optimization algorithm where the metaheuristic rapidly
finds feasible solutions that provide candidate upper bounds for the B&B
algorithm which runs simultaneously. The MCTS additionally provides a candidate
fleet composition to initiate the B&B search. Experiments show that the
proposed approach results in significant improvements in computation time and
convergence to the optimal solution.Comment: Submitted to the IEEE Intelligent Vehicles Symposium 202
Burkholderia pseudomallei traced to water treatment plant in Australia.
Burkholderia pseudomallei was isolated from environmental specimens 1 year after an outbreak of acute melioidosis in a remote coastal community in northwestern Australia. B. pseudomallei was isolated from a water storage tank and from spray formed in a pH-raising aerator unit. Pulsed-field gel electrophoresis confirmed the aerator and storage tank isolates were identical to the outbreak strain, WKo97
Self-sampling tools to increase cancer screening among underserved patients: A pilot randomized controlled trial
BACKGROUND: Screening can reduce cancer mortality, but uptake is suboptimal and characterized by disparities. Home-based self-sampling can facilitate screening for colorectal cancer (with stool tests, eg, fecal immunochemical tests) and for cervical cancer (with self-collected human papillomavirus tests), especially among patients who face barriers to accessing health care. Additional data are needed on feasibility and potential effects of self-sampling tools for cancer screening among underserved patients.
METHODS: We conducted a pilot randomized controlled trial with patients (female, ages 50-65 years, out of date with colorectal and cervical cancer screening) recruited from federally qualified health centers in rural and racially segregated counties in Pennsylvania. Participants in the standard-of-care arm (n = 24) received screening reminder letters. Participants in the self-sampling arm (n = 24) received self-sampling tools for fecal immunochemical tests and human papillomavirus testing. We assessed uptake of screening (10-week follow-up), self-sampling screening outcomes, and psychosocial variables. Analyses used Fisher exact tests to assess the effect of study arm on outcomes.
RESULTS: Cancer screening was higher in the self-sampling arm than the standard-of-care arm (colorectal: 75% vs 13%, respectively, odds ratio = 31.32, 95% confidence interval = 5.20 to 289.33; cervical: 79% vs 8%, odds ratio = 72.03, 95% confidence interval = 9.15 to 1141.41). Among participants who returned the self-sampling tools, the prevalence of abnormal findings was 24% for colorectal and 18% for cervical cancer screening. Cancer screening knowledge was positively associated with uptake (P \u3c .05).
CONCLUSIONS: Self-sampling tools can increase colorectal and cervical cancer screening among unscreened, underserved patients. Increasing the use of self-sampling tools can improve primary care and cancer detection among underserved patients.
CLINICAL TRIALS REGISTRATION NUMBER: STUDY00015480
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Microstructure casts during AIWEX : a summary
The Arctic Internal Wave Experiment (AIWEX) was designed to study the internal wave and microstructure fields in the Beaufort Sea in the early spring. A major goal of the experiment was to verify the hypothesis that the internal wave and microstructure fields beneath the ice are far less energetic than in temperate oceans. Major goals of the microstructure measurements were to characterize the double-diffusive staircase region in the depth range 300-450m, to estimate the heat flux from the deep Atlantic water into shallower depth zones, and to assess the influence of mesoscale and submesoscale eddies on turbulence beneath the ice.
An ice camp was established in mid March 1985 to accomplish these goals. The camp was occupied until the first week of May, and microstructure casts were made beginning March 20 (Julian Day 79). Microstructure profiling continued until April 26; no profiles were obtained from April 4 through April 16 because of a malfunction in the data acquisition system. Over 700 casts were made spanning the range 0 to 500 m. The time between profiles averaged 20 minutes for a full-range profile. Not all casts covered the full depth range; some yo-yo casts through selected depth ranges were made to obtain detailed information on a shorter time scale. The ice camp drifted with a typical speed of 5 to 10 cm/s, although there were periods when the speed was as slow as 1 cm/s
Scaling study of the pion electroproduction cross sections and the pion form factor
The H()n cross section was measured for a range of
four-momentum transfer up to =3.91 GeV at values of the invariant
mass, , above the resonance region. The -dependence of the longitudinal
component is consistent with the -scaling prediction for hard exclusive
processes. This suggests that perturbative QCD concepts are applicable at
rather low values of . Pion form factor results, while consistent with the
-scaling prediction, are inconsistent in magnitude with perturbative QCD
calculations. The extraction of Generalized Parton Distributions from hard
exclusive processes assumes the dominance of the longitudinal term. However,
transverse contributions to the cross section are still significant at
=3.91 GeV.Comment: 6 pages, 3 figure
Obesity: A Biobehavioral Point of View
Excerpt: If you ask an overweight person, “Why are you fat?’, you will, almost invariably, get the answer, “Because 1 eat too much.” You will get this answer in spite of the fact that of thirteen studies, six find no significant differences in the caloric intake of obese versus nonobese subjects, five report that the obese eat significantly less than the nonobese, and only two report that they eat significantly more
Nuclear transparency and effective kaon-nucleon cross section from the A(e, e'K+) reaction
We have determined the transparency of the nuclear medium to kaons from
measurements on C, Cu, and Au targets.
The measurements were performed at the Jefferson Laboratory and span a range in
four-momentum-transfer squared Q=1.1 -- 3.0 GeV. The nuclear
transparency was defined as the ratio of measured kaon electroproduction cross
sections with respect to deuterium, (). We further
extracted the atomic number () dependence of the transparency as
parametrized by and, within a simple model assumption,
the in-medium effective kaon-nucleon cross sections. The effective cross
sections extracted from the electroproduction data are found to be smaller than
the free cross sections determined from kaon-nucleon scattering experiments,
and the parameter was found to be significantly larger than those
obtained from kaon-nucleus scattering. We have included similar comparisons
between pion- and proton-nucleon effective cross sections as determined from
electron scattering experiments, and pion-nucleus and proton-nucleus scattering
data.Comment: 7 pages, 5 figure
Study of the A(e,e') Reaction on H, H, C, Al, Cu and Au
Cross sections for the p()n process on H, H, C,
Al, Cu and Au targets were measured at the Thomas
Jefferson National Accelerator Facility (Jefferson Lab) in order to extract the
nuclear transparencies. Data were taken for four-momentum transfers ranging
from =1.1 to 4.8 GeV for a fixed center of mass energy of =2.14
GeV. The ratio of and was extracted from the measured
cross sections for H, H, C and Cu targets at = 2.15
and 4.0 GeV allowing for additional studies of the reaction mechanism. The
experimental setup and the analysis of the data are described in detail
including systematic studies needed to obtain the results. The results for the
nuclear transparency and the differential cross sections as a function of the
pion momentum at the different values of are presented. Global features
of the data are discussed and the data are compared with the results of model
calculations for the p()n reaction from nuclear targets.Comment: 28 pages, 19 figures, submited to PR
Correlated Strength in Nuclear Spectral Function
We have carried out an (e,e'p) experiment at high momentum transfer and in
parallel kinematics to measure the strength of the nuclear spectral function
S(k,E) at high nucleon momenta k and large removal energies E. This strength is
related to the presence of short-range and tensor correlations, and was known
hitherto only indirectly and with considerable uncertainty from the lack of
strength in the independent-particle region. This experiment confirms by direct
measurement the correlated strength predicted by theory.Comment: 4 pages, 2 figures, accepted by Phys. Rev. Let
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