I Laughed Until I Cried: The Tragicomedy of Harold Pinter\u27s \u3ci\u3e The Homecoming \u3c/i\u3e

There appears to be a disconnect between the actual events of Harold Pinter\u27s The Homecoming and the scholarly work devoted to the play--while each of the main characters are morally problematic, it is only the play\u27s sole female character, Ruth, whose morality is questioned. This schism in which Ruth is questioned but others are not stems primarily from the time in which most of this criticism occurred: before post-structuralist understandings of gender undermined our presuppositions about the sexes. The Homecoming was written on the cusp of second-wave feminism, the movement focusing mainly on the legal and social equality of women, and it seems as though Pinter sensed a shift in paradigm in which feminist theorists called into question the phallogocentric language with which they were attempting to describe their subjects. A post-structuralist feminist reading of the play recognizes the problematic ways in which men are considered to have essential qualities, too. Pinter\u27s The Homecoming encourages its audience to reconsider their conditioned perception of gender in society because the play induces the audience, in our real-life roles as conditioned observers, to misread the play; through undermining the false binary of humor and tragedy, Pinter asks the audience to reassess the supposed binary of male/female as it occurs in the play

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead