Congenital lung mass in an asymptomatic patient

No Abstract. South African Medical Journal Vol. 96(6) 2006: 512-51

Congenital lung mass in anasymptomatic patient

A routine 20-week antenatal ultrasound scan showed a congenital lesion of the left fetal lung, measuring approximately 25 mm x 25 mm x 30 mm. The mass showed no sonographic change through the remainder of an uneventful pregnancy. The baby was delivered by elective caesarean section at 38 weeks' gestation, with a birth weight of 2 900 g, and had no postnatal complications. A chest radiograph performed in the early neonatal period was normal, but a contrasted single-slice helical computed tomography (CT) chest scan at age 6 weeks demonstrated the small, oval, solid mass in the left lower lobe, with no associated mediastinal shift (Fig. 1). The vascular supply of the lesion could not be identified on this scan

Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients

Development of long-lasting anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) T-cell responses in persons with multiple sclerosis (pwMS) treated with ocrelizumab is questioned

A postmarket safety comparison of 2 vaccination strategies for measles, mumps, rubella and varicella in Italy

It is strategically important to monitor the safety profile of vaccination schedules in order to achieve and maintain high levels of coverage. We analyzed the cohort of individuals actively invited for measles, mumps, rubella and varicella (MMRV) vaccination in the Veneto region (north-east Italy) from 8/1/2013 to 7/31/2014, assessing the onset of adverse events (AE) relating to 2 different vaccination strategies for MMRV (MMR+V vs MMRV). During the vaccination session at 14 months old, parents were given a form for recording local and systemic reactions to vaccinations for 4 weeks afterwards. Overall, 12,288 forms were returned, and 84.6% of them were included in this analysis (5,130 relating to MMR+V and 5,265 to MMRV); 37.3% of the sample reported no AEs, with no difference between the 2 groups. Local reactions were more common in the MMR+V group (9.6% vs 2.9%; RR 3.33; 95% CI 2.79\u20133.98), while there was no difference in general reactions between the 2 groups (50% MMR+V vs 52% MMRV). The events most often reported were \u201cfever <39.5\ub0C,\u201d which was more frequently associated with the MMRV strategy (p<0.001), and \u201cskin blotches and marks,\u201d which occurred more often in the MMR+V group (p<0.001). Reports of \u201cfever 6539.5\ub0C\u201d were equally distributed between the 2 groups. Sixteen cases of febrile seizures were reported (0.14% in the MMR+V group and 0.17% in the MMRV group). Similar safety profiles were identified for the 2 vaccination strategies. Although the method used to record reactions to vaccination demanded considerable resources, it enabled important information to be collected on parents' perception of the AEs occurring in response to their child's vaccination