Preface

This article serves as the preface to a special issue of the Victoria University of Wellington Law Review including the papers presented at the inaugural New Zealand Private Law Scholars' Roundtable in February 2016. The author, Justice Christine French of the Court of Appeal of New Zealand, praises the papers for their quality of work, the broad range of topics, and the collaborative nature of the work and its New Zealand setting.&nbsp

The mediating role of avoidance coping upon the relationship between early maladaptive schemas, anxiety and depression

This study examined the mediating role of Maladaptive Emotion-focused coping (MEFC) on the relationship between Early Maladaptive Schemas (EMS), anxiety and depression

Minnesota Modern: Era of Innovation

The National Trust for Historic Preservation (NTHP), with the cooperation and support of the Preservation Alliance of Minnesota, Preserve Minneapolis, DOCOMOMO MN, and the Minnesota Historical Society, hosted a two-day Modern Module in Minneapolis and St. Paul on October 27 and October 28, 2009. This booklet is a companion publication to the The National Trust for Historic Preservation (NTHP), with the cooperation and support of the Preservation Alliance of Minnesota, Preserve Minneapolis, DOCOMOMO MN, and the Minnesota Historical Society, hosted a two-day Modern Module in Minneapolis and St. Paul on October 27 and October 28, 2009

Aspen Modern: America’s International Resort

The Aspen Modern event held on July 28, 2010 was presented by the National Trust for Historic Preservation, in partnership with the City of Aspen Community Development Department, the Aspen Art Museum, the Aspen Historical Society, the Aspen Institute, and Spring Board Aspen, with support from the National Endowment for the Arts and the Henry Luce Foundation. This full-color booklet highlights the modern architecture of Aspen, Colorado

Los Angeles Modern: City of Tomorrow

The National Trust for Historic Preservation (NTHP) and the Los Angeles Conservancy (LAC) hosted the two-day inaugural Modern Module in Los Angeles on September 30 and October 1, 2009. This full-color booklet highlights Modern and recent past resources in greater Los Angeles Area

Target value design: using collaboration and a lean approach to reduce construction cost

Target Costing is an effective management technique that has been used in manufacturing for decades to achieve cost predictability during new products development. Adoption of this technique promises benefits for the construction industry as it struggles to raise the number of successful outcomes and certainty of project delivery in terms of cost, quality and time. Target Value Design is a management approach that takes the best features of Target Costing and adapts them to the peculiarities of construction. In this paper the concept of Target Value Design is introduced based on the results of action research carried out on 12 construction projects in the USA. It has been shown that systemic application of Target Value Design leads to significant improvement of project performance – the final cost of projects was on average 15% less than market cost. The construction industry already has approaches that have similarities with elements of the Target Value Design process or uses the same terminology, e.g. Partnering and Target Cost Contracts, Cost planning, etc. Following an exploration of the similarities and differences Target Value Design is positioned as a form of Target Costing for construction that offers a more reliable route to successful projects outcomes

2013 Ruby Yearbook

A digitized copy of the 2013 Ruby, the Ursinus College yearbook.https://digitalcommons.ursinus.edu/ruby/1116/thumbnail.jp

Christine Weston Correspondence

Entries include the brief biographical information of an author from Brewer, Maine, born and raised in India, and living at times in a convent where she was sent during World War II, a typed biography of Weston, a typed letter on Salmon Pool Farm, Brewer, MAINE, stationery presenting Be Thou the Bride, and typed transcripts of letters that present her works of fiction set in India and Maine such as Indigo, The Devil\u27s Foot, The Dark Wood, and her book for younger people Bhimsa, The Dancing Bear, three newspaper clippings are presented together: an illustrated sketch of Weston with a caption, a book review, and an announcement on her receipt of a John Simon Guggenheim memorial award following the publication of her first book as well as an admiring book review of Weston\u27s 1970 novel The Hoopoe

Mouse Models to Understand Mutagenic Outcomes and Illegitimate Repair of DNA Damage

Maintenance of genome integrity is critical to prevent cell death or disease. Illegitimate repair of chromosomal DNA breaks can lead to mutations and genome rearrangements which are a well-known hallmark of multiple cancers and disorders. Endogenous causes of DNA double-strand breaks (DSBs) include reactive oxygen species (ROS) and replication errors while exogenous causes of DNA breaks include ionizing radiation, UV radiation, alkylating agents, and inhibitors of topoisomerase II (Top2). Recent evidence suggests that a growing list of environmental agents or toxins and natural dietary compounds also cause DNA breaks. Understanding the consequences of exposure to a broad spectrum of DSB-inducing agents has significant implications for understanding mutagenicity, genome stability and human health. This chapter will review in vivo mouse models designed to measure DNA damage and mutagenicity, and illegitimate repair of DNA DSBs caused by exposure to environmental agents

BAFF production by antigen‐presenting cells provides T cell co‐stimulation

The B cell‐activating factor from the tumor necrosis factor family (BAFF) is an important regulator of B cell immunity. Recently, we demonstrated that recombinant BAFF also provides a co‐stimulatory signal to T cells. Here, we studied expression of BAFF in peripheral blood leukocytes and correlated this expression with BAFF T cell co‐stimulatory function. BAFF is produced by antigen‐presenting cells (APC). Blood dendritic cells (DC) as well as DC differentiated in vitro from monocytes or CD34+ stem cells express BAFF mRNA. Exposure to bacterial products further up‐regulates BAFF production in these cells. A low level of BAFF transcription, up‐regulated upon TCR stimulation, was also detected in T cells. Functionally, blockade of endogenous BAFF produced by APC and, to a lesser extent, by T cells inhibits T cell activation. Altogether, this indicates that BAFF may regulate T cell immunity during APC-T cell interactions and as an autocrine factor once T cells have detached from the AP