1,264 research outputs found
Planar maps, circle patterns and 2d gravity
Via circle pattern techniques, random planar triangulations (with angle
variables) are mapped onto Delaunay triangulations in the complex plane. The
uniform measure on triangulations is mapped onto a conformally invariant
spatial point process. We show that this measure can be expressed as: (1) a sum
over 3-spanning-trees partitions of the edges of the Delaunay triangulations;
(2) the volume form of a K\"ahler metric over the space of Delaunay
triangulations, whose prepotential has a simple formulation in term of ideal
tessellations of the 3d hyperbolic space; (3) a discretized version (involving
finite difference complex derivative operators) of Polyakov's conformal
Fadeev-Popov determinant in 2d gravity; (4) a combination of Chern classes,
thus also establishing a link with topological 2d gravity.Comment: Misprints corrected and a couple of footnotes added. 42 pages, 17
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An efficient methodology for modeling complex computer codes with Gaussian processes
Complex computer codes are often too time expensive to be directly used to
perform uncertainty propagation studies, global sensitivity analysis or to
solve optimization problems. A well known and widely used method to circumvent
this inconvenience consists in replacing the complex computer code by a reduced
model, called a metamodel, or a response surface that represents the computer
code and requires acceptable calculation time. One particular class of
metamodels is studied: the Gaussian process model that is characterized by its
mean and covariance functions. A specific estimation procedure is developed to
adjust a Gaussian process model in complex cases (non linear relations, highly
dispersed or discontinuous output, high dimensional input, inadequate sampling
designs, ...). The efficiency of this algorithm is compared to the efficiency
of other existing algorithms on an analytical test case. The proposed
methodology is also illustrated for the case of a complex hydrogeological
computer code, simulating radionuclide transport in groundwater
A One-and-Half Stage Pedestrian Detector
International audiencePedestrian detection is a specific instance of the more general problem of object detection in computer vision. A balance between detection accuracy and speed is a desirable trait for pedestrian detection systems in many applications such as self-driving cars. In this paper, we follow the wisdom of " and less is often more" to achieve this balance. We propose a lightweight mechanism based on semantic segmentation to reduce the number of anchors to be processed. We furthermore unify this selection with the intra-anchor feature pooling strategy adopted in high performance two-stage detectors such as Faster-RCNN. Such a strategy is avoided in one-stage detectors like SSD in favour of faster inference but at the cost of reducing the accuracy vis-Ă -vis two-stage detectors. However our anchor selection renders it practical to use feature pooling without giving up the inference speed. Our proposed approach succeeds in detecting pedestrians with state-of-art performance on caltech-reasonable and ciypersons datasets with inference speeds of ⌠32 fps
Exploiting Light Interferences to Generate Micrometer-High Superstructures from Monomeric Azo Materials with Extensive Orientational Mobility
Photochromic azo materials have stirred considerable interest for their ability to mechanically respond to polarized light through large photo-induced migration and orientation processes. In order to apprehend the microscopic dynamics behind the extensive mass transport occurring under interferential illumination, two azo compounds differing by their propen-sity to form hydrogen bonds are synthesized and processed as nondoped glassy thin films. Interferential irradiation using polarization and intensity patterns reveals fully distinct responses. Regular nanometer-high surface relief gratings transform into micrometer superstructures with an ampli-tude ten times higher than the initial film thickness when using the latter polarization. Systematic comparisons between the azo materials in terms of thermal properties, photochromism in solution and in the solid state, and photomigration are carried out. The progressive formation of super-structures is ascribed to two successive processes. The first one relates to fast photoinduced migration due to the impinging structured light, and the second one is promoted by slower thermally activated âzig-zagâ-like diffu-sion and Z-E thermal relaxation, which in turn requests high orientational mobility of the azo compounds and causes large nanomechanical changes. Such studies should provide novel structural guidelines in terms of material fluidity to rapidly achieve highly structured and rewritable materials at lilogwht irradiance
Novel Transgenic Mice for Inducible Gene Overexpression in Pancreatic Cells Define Glucocorticoid Receptor-Mediated Regulations of Beta Cells
Conditional gene deletion in specific cell populations has helped the understanding of pancreas development. Using this approach, we have shown that deleting the glucocorticoid receptor (GR) gene in pancreatic precursor cells leads to a doubled beta-cell mass. Here, we provide genetic tools that permit a temporally and spatially controlled expression of target genes in pancreatic cells using the Tetracycline inducible system. To efficiently target the Tetracycline transactivator (tTA) in specific cell populations, we generated Bacterial Artificial Chromosomes (BAC) transgenic mice expressing the improved Tetracycline transactivator (itTA) either in pancreatic progenitor cells expressing the transcription factor Pdx1 (BAC-Pdx1-itTA), or in beta cells expressing the insulin1 gene (BAC-Ins1-itTA). In the two transgenic models, itTA-mediated activation of reporter genes was efficient and subject to regulation by Doxycycline (Dox). The analysis of a tetracycline-regulated LacZ reporter gene shows that in BAC-Pdx1-itTA mice, itTA is expressed from embryonic (E) day 11.5 in all pancreatic precursor cells. In the adult pancreas, itTA is active in mature beta, delta cells and in few acinar cells. In BAC-Ins1-itTA mice tTA is active from E13.5 and is restricted to beta cells in fetal and adult pancreas. In both lines, tTA activity was suppressed by Dox treatment and re-induced after Dox removal. Using these transgenic lines, we overexpressed the GR in selective pancreatic cell populations and found that overexpression in precursor cells altered adult beta-cell fraction but not glucose tolerance. In contrast, GR overexpression in mature beta cells did not alter beta-cell fraction but impaired glucose tolerance with insufficient insulin secretion. In conclusion, these new itTA mouse models will allow fine-tuning of gene expression to investigate gene function in pancreatic biology and help us understand how glucocorticoid signaling affects on the long-term distinct aspects of beta-cell biology
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