527 research outputs found

    Hopf-algebra description of noncommutative-spacetime symmetries

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    In the study of certain noncommutative versions of Minkowski spacetime there is still a large ambiguity concerning the characterization of their symmetries. Adopting as our case study the kappaMinkowski noncommutative space-time, on which a large literature is already available, we propose a line of analysis of noncommutative-spacetime symmetries that relies on the introduction of a Weyl map (connecting a given function in the noncommutative Minkowski with a corresponding function in commutative Minkowski) and of a compatible notion of integration in the noncommutative spacetime. We confirm (and we establish more robustly) previous suggestions that the commutative-spacetime notion of Lie-algebra symmetries must be replaced, in the noncommutative-spacetime context, by the one of Hopf-algebra symmetries. We prove that in kappaMinkowski it is possible to construct an action which is invariant under a Poincare-like Hopf algebra of symmetries with 10 generators, in which the noncommutativity length scale has the role of relativistic invariant. The approach here adopted does leave one residual ambiguity, which pertains to the description of the translation generators, but our results, independently of this ambiguity, are sufficient to clarify that some recent studies (gr-qc/0212128 and hep-th/0301061), which argued for an operational indistiguishability between theories with and without a length-scale relativistic invariant, implicitly assumed that the underlying spacetime would be classical.Comment: 20 pages, no figures, LaTex. This version has exactly the same technical content as version 1, but the observation reported in Section VII is discussed more pedagogicall

    The maximum likelihood degree of Fermat hypersurfaces

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    We study the critical points of the likelihood function over the Fermat hypersurface. This problem is related to one of the main problems in statistical optimization: maximum likelihood estimation. The number of critical points over a projective variety is a topological invariant of the variety and is called maximum likelihood degree. We provide closed formulas for the maximum likelihood degree of any Fermat curve in the projective plane and of Fermat hypersurfaces of degree 2 in any projective space. Algorithmic methods to compute the ML degree of a generic Fermat hypersurface are developed throughout the paper. Such algorithms heavily exploit the symmetries of the varieties we are considering. A computational comparison of the different methods and a list of the maximum likelihood degrees of several Fermat hypersurfaces are available in the last section.Comment: Final version. Accepted for publication on Journal of Algebraic Statistic

    Enabling RAN Slicing Through Carrier Aggregation in mmWave Cellular Networks

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    The ever increasing number of connected devices and of new and heterogeneous mobile use cases implies that 5G cellular systems will face demanding technical challenges. For example, Ultra-Reliable Low-Latency Communication (URLLC) and enhanced Mobile Broadband (eMBB) scenarios present orthogonal Quality of Service (QoS) requirements that 5G aims to satisfy with a unified Radio Access Network (RAN) design. Network slicing and mmWave communications have been identified as possible enablers for 5G. They provide, respectively, the necessary scalability and flexibility to adapt the network to each specific use case environment, and low latency and multi-gigabit-per-second wireless links, which tap into a vast, currently unused portion of the spectrum. The optimization and integration of these technologies is still an open research challenge, which requires innovations at different layers of the protocol stack. This paper proposes to combine them in a RAN slicing framework for mmWaves, based on carrier aggregation. Notably, we introduce MilliSlice, a cross-carrier scheduling policy that exploits the diversity of the carriers and maximizes their utilization, thus simultaneously guaranteeing high throughput for the eMBB slices and low latency and high reliability for the URLLC flows.Comment: 8 pages, 8 figures. Proc. of the 18th Mediterranean Communication and Computer Networking Conference (MedComNet 2020), Arona, Italy, 202

    Comment on “early efficacy of intra-articular HYADD¼ 4 (Hymovis¼) injections for symptomatic knee osteoarthritis”

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    We read with great interest the study by Priano titled“Early efficacy of intra-articular HYADD¼ 4 (Hymovis¼) injections for symptomatic knee osteoarthritis.” 1 The author would like to explore the efficacy of intra-articular HYADD 4 (Hymovis) injections for symptomatic knee osteoarthritis. Results from this study are very interesting and promising from a clinical aspect; however, we believe that studying patient’sclinical status with visual analog scale and Western Ontario and McMaster Universities Arthritis Index scale should be supported by biomechanical information. From this point of view, to have more data that could influence the clinical practice, it is important to note the possible action that intraarticular injections of different kinds of hyaluronic acid could have on walking biomechanics using an objective measurement tool as gait analysis. In our opinion, the work by Priano1 is promising because it investigates the efficacy of a new formulation of hyaluronic acid. Nowadays, many hyaluronic acid formulations are approved for clinical use in Europe and the United States. Furthermore, hyaluronic acid injections’ efficacy has been demonstrated also in hip osteoarthritis. 2 However, even if these formulations differ in their chemical– physical properties, joint space half-life, rheological properties, and clinical efficacy, there are few studies that investigate hyaluronic acid’s possible action from a biomechanical point of view. 3,4 From this point of view, we believe that osteoarthritis management and rehabilitation should be prescribed after an objective analysis of functional walking alterations using gait analysis instrumentations. The use of gait analysis should be desirable during diagnosis and follow-up. In fact, it is capable to identify different walking patterns in patient with osteoarthritis of the lower limbs, whereas the radiology can evaluate the status of the joint’s structures

    A Multiscale Thermo-Fluid Computational Model for a Two-Phase Cooling System

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    In this paper, we describe a mathematical model and a numerical simulation method for the condenser component of a novel two-phase thermosyphon cooling system for power electronics applications. The condenser consists of a set of roll-bonded vertically mounted fins among which air flows by either natural or forced convection. In order to deepen the understanding of the mechanisms that determine the performance of the condenser and to facilitate the further optimization of its industrial design, a multiscale approach is developed to reduce as much as possible the complexity of the simulation code while maintaining reasonable predictive accuracy. To this end, heat diffusion in the fins and its convective transport in air are modeled as 2D processes while the flow of the two-phase coolant within the fins is modeled as a 1D network of pipes. For the numerical solution of the resulting equations, a Dual Mixed-Finite Volume scheme with Exponential Fitting stabilization is used for 2D heat diffusion and convection while a Primal Mixed Finite Element discretization method with upwind stabilization is used for the 1D coolant flow. The mathematical model and the numerical method are validated through extensive simulations of realistic device structures which prove to be in excellent agreement with available experimental data

    Simulating the Impact on the Local Economy of Alternative Management Scenarios for Natural Areas

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    This working paper estimates the impact on the local economy of the High Garda Natural Park of alternative management scenarios for the West Garda Regional Forest. The local economy is specialized in tourist services and strongly linked to the tourist presence and their level of expenditure. We wish to investigate the effects of the participative management strategy, which takes into account users preferences and the non-participative strategy, using the SAM multiplier analysis. The local SAM has been constructed considering three sectors: agriculture, tourism and a third aggregate sector including all the other activities. The resident population has been divided into two categories: residents employed in the tourist sector and the remaining resident population. The SAM analysis shows that the accounting representation of the local economy is meaningful and that the participative program, if chosen by the central regional management, would be the most desirable program also at the local level.Tourism, SAM, Multiplier analysis

    Linking ROS Levels to Autophagy: The Key Role of AMPK

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    Oxygen reactive species (ROS) are a group of molecules generated from the incomplete reduction of oxygen. Due to their high reactivity, ROS can interact with and influence the function of multiple targets, which include DNA, lipids, and proteins. Among the proteins affected by ROS, AMP-activated protein kinase (AMPK) is considered a major sensor of the intracellular energetic status and a crucial hub involved in the regulation of key cellular processes, like autophagy and lysosomal function. Thanks to these features, AMPK has been recently demonstrated to be able to perceive signals related to the variation of mitochondrial dynamics and to transduce them to the lysosomes, influencing the autophagic flux. Since ROS production is largely dependent on mitochondrial activity, through the modulation of AMPK these molecules may represent important signaling agents which participate in the crosstalk between mitochondria and lysosomes, allowing the coordination of these organelles' functions. In this review, we will describe the mechanisms through which ROS activate AMPK and the signaling pathways that allow this protein to affect the autophagic process. The picture that emerges from the literature is that AMPK regulation is highly tissue-specific and that different pools of AMPK can be localized at specific intracellular compartments, thus differentially responding to altered ROS levels. For this reason, future studies will be highly advisable to discriminate the specific contribution of the activation of different AMPK subpopulations to the autophagic pathway

    Prvi zapis o novoj obojanosti kirnje zlatice, Epinephelus costae (Steindachner, 1878) (Actinopterygii: Serranidae) i prvi zapis o leucizmu ugora, Conger conger (Linnaeus, 1758) (Actinopterygii: Congridae): građanski doprinos znanosti

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    In many fish, color patterns are striking features and can play an important role in both natural and sexual selection. Furthermore, details of color patterns are in some cases valid tools for species identification. However, fish can also show some genetic abnormalities, such as albinism and leucism. In this research, we report for the first time a new color pattern for Epinephelus costae (Steindachner, 1878), for which it is known an ontogenetic shift in color pattern, and the first case of leucism in Conger conger (Linnaeus, 1758).Kod mnogih riba obojanost ima upečatljiva obiljeĆŸja i moĆŸe igrati vaĆŸnu ulogu kako u prirodnom tako i u spolnom odabiru. Detalji o uzorcima boja u nekim su slučajevima valjani alat za identifikaciju vrsta. Međutim, riba moĆŸe pokazati i neke genetske abnormalnosti, poput albinizma i leucizma. U ovom istraĆŸivanju prvi put izvjeơćujemo o novoj obojanosti Epinephelus costae (Steindachner, 1878.) i o prvom slučaju leucizma kod ugora, Conger conger (Linnaeus, 1758)

    Boiling on a tube bundle:heat transfer, pressure drop and flow patterns

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    The complexity of the two-phase flow in a tube bundle presents important problems in the design and understanding of the physical phenomena taking place. The working conditions of an evaporator depend largely on the dynamics of the two-phase flow that in turn influence the heat exchange and the pressure drop of the system. A characterization of the flow dynamics, and possibly the identification of the flow pattern in the tube bundle, in thus expected to lead to a better understanding of the phenomena and to reveal on the mechanisms governing the tube bundle. Therefore, the present study aims at providing further insights into two-phase bundle flow through a new visualization system able to provide for the first time a view of the flow in the core of a tube bundle. In addition, the measurement of the light attenuation of a laser beam through the two-phase flow and measurement of the high frequency pressure fluctuations with a piezo-electric pressure transducer are used to characterize the flow. The design and the validation of this new instrumentation also provided a method for the detection of dry-out in tube bundles. This was achieved by a laser attenuation technique, flow visualization, and estimation of the power spectrum of the pressure fluctuation. The current investigation includes results for two different refrigerants, R134a and R236fa, three saturations temperatures Tsat = 5, 10 and 15 °C, mass velocities ranging from 4 to 40 kg/sm2 in adiabatic and diabatic conditions (several heat fluxes). Measurement of the local heat transfer coefficient and two-phase frictional pressure drop were obtained and utilized to improve the current prediction methods. The heat transfer and pressure drop data were supported by extensive characterization of the two-phase flow, which was to improve the understanding of the two-phase flow occurring in tube bundles
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