Solving problems through engineering design: An exploratory study with pre-service teachers

A possible pathway to achieve disciplinary integration is through the use of the Engineering Design (ED) process, starting with problems in a real context that enable the mobilization of concepts from various disciplinary areas. The study reported in this paper aims to analyze the performance underlying the use of the ED process in solving authentic problems in a STEAM perspective, with future teachers of elementary education. We adopted a qualitative and interpretative methodology, with an exploratory design, where data were collected through participant observation, documents, artefacts and photographic records. The results are discussed, taking into account previous research and the data collected throughout the classes, where future teachers solved a problem task and created an artefact and a poster. Preliminary results show that the participants valued the experience and were actively engaged, showing persistence and motivation in solving the problem in a collaborative way, through the different steps of the ED cycle. This approach constituted an opportunity to favor the establishment of connections between different areas, such as mathematics, sciences or arts, detecting the possibility of integrating previously learned concepts. Difficulties were evidenced in the identification of some underlying mathematical and physical sciences concepts, particularly in the mobilization of an adequate scientific language while arguing and making decisions, or in accurately justifying the need to improve the designed plan.0D1E-4824-1244 | Ana Cristina Coelho Barbosainfo:eu-repo/semantics/publishedVersio

Production of co-amorphous materials with therapeutic activity

Poster presented at the 2nd International Congress of CiiEM: “Translational Research and Innovation in Human and Health Sciences”. Egas Moniz, Caparica, Portugal, 11-13 June 2017N/

Solving authentic problems through engineering design

The importance of STEAM education in pre- paring students to deal with societal challenges is nowa- days an international recommendation. We may find different perspectives concerning STEAM education and the integration of its disciplines. A possible pathway to achieve a balanced integration is through Engineering Design (ED), starting from problems of reality that enable the articulated mobilization of concepts from various dis- ciplinary areas, promoting interdisciplinary where team- work and context play a fundamental role. This article reports a study with primary preservice teachers (6?12 years old) that aims to analyze the learning displayed and the difficulties underlying the usage of ED in solving STEAM problems. The participants were 45 preservice teachers. We adopted a qualitative methodology, and data were collected through observation, documents, artifacts, and photos. The preliminary results show a very positive reaction of the participants to the experi- ence of solving real context problems collaboratively and mobilizing mathematical and physical science concepts in an integrated way. We identified active engagement, persistence, and motivation in the creation of a model that fulfilled the requested conditions. Difficulties were evidenced in the identification of some concepts and the mobilization of adequate scientific language in the argumentation of decisions.0D1E-4824-1244 | Ana Cristina Coelho Barbosainfo:eu-repo/semantics/publishedVersio

Addressing drug solubility problems : a case-study

Poster presented at the 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting. 24-25 Julho 2018, LisboaN/

Development of an at-line method to monitor the conversion of amorphous into crystalline Olanzapine, in dry blends of wet masses

Abstract of the poster presented at the 3rd European Conference on Pharmaceutics. 25-26 march 2019, Bologne, ItalyN/

Assessment of the stability of co-amorphous Olanzapine in tablets

Abstract of the poster presented at the 4th International Congress of CiiEM - "Health, Well-being and Ageing in the XXI Century." 2-5 June 2019, Monte de Caparica, PortugalN/

Drug-excipient and drug-drug mixtures : a pathway for the production of co-amorphous entities

Abstract of the communication presented at the 3rd International Congress of CiiEM ‘Research and Innovation in Human and Health Sciences’. Campus Egas Moniz, Caparica, Portugal, June 20-22, 2018N/

Cohesiveness of powdered co-amorphous Olanzapine and impact on tablet production

Communication abstract: Proceedings of the 5th International Congress of CiiEM - Reducing inequalities in Health and Society, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from June 16th to 18th, 2021.This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.The evaluation of the processability of co-amorphous mixtures is of paramount importance since these systems are increasingly used to address the poor solubility presented by most of the drugs in research and development. This work shows that co-amorphous olanzapine powders present higher cohesiveness than their crystalline counterpart and resulted in the production of tablets with a higher tensile strength and a slower release of the drug. As a result, this work demonstrates that despite the solubility advantages of co-amorphous mixtures, consideration should be given to the downstream processing of formulations containing such materials.info:eu-repo/semantics/publishedVersio

Characterization and stability of co-amorphous systems containing Olanzapine and sulfonic acids

Abstract of the communication presented at the 4th International Congress of CiiEM - "Health, Well-being and Ageing in the XXI Century." 2-5 June 2019, Campus Egas Moniz, Monte de Caparica, PortugalN/

Co-formability, solubility enhancement and stability of Olanzapine co-amorphous systems produced with different co-formers

Abstract of the poster presented at the 4th International Congress of CiiEM - "Health, Well-being and Ageing in the XXI Century." 2-5 June 2019, Campus Egas Moniz, Monte de Caparica, PortugalN/