56 research outputs found

    A Synthesis of Risks in Dairy Value Chains in Southern Africa: Cases of South Africa and Zimbabwe

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    An increase in frequency and intensity of slow- and fast-onset disasters in Southern Africa has crippled milk producers’ value chain with catastrophic effects to consumers. Milk production is vulnerable to disruptions from natural disasters, poor transport and infrastructure. The chapter considers the cases of South Africa and Zimbabwe, two countries that have organized dairy production. Against this bleak backdrop, this chapter explores the contribution of the milk industry to the economy and the benefits to consumers of milk and dairy products. The chapter also identifies the key players in the dairy supply chain in Southern Africa. It explores different types of disaster risks prevalent in Southern Africa and how they affect the production of raw and processed milk along dairy supply chains. It further interrogates risk management strategies employed by the key players to mitigate these risks to make dairy supply chains sustainable. This chapter reviewed literature and analyzed governments, nongovernmental organizations, and industries’ documents with the aim to present value chain resilience strategies. This chapter also presents an insight into the policymakers and milk industries on the risk reduction strategies that are employed to mitigate the effects of risks on the milk and dairy products’ value chain

    Algal Nanoparticles: Synthesis and Biotechnological Potentials

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    A nanoparticle can be defined as a small object that behaves as a whole unit in terms of its transport and properties. Nanoparticles are sized between 1 and 100 nm in diameter. Nanoparticles can act against the microbes in multiple ways, and the microbes are less likely to develop resistance against nanoparticles because it requires multiple gene mutations. The large surface-to-volume ratio of nanoparticles, their ability to easily interact with other particles, and several other features make them attractive tools in various fields. Nanoparticles are widely used various fields such as electronics, cosmetics, biomedical, and biotechnology. Nanoparticles can be synthesized by physical methods such as attrition, pyrolysis, and using some wet chemical methods. The physical and chemical methods have various drawbacks such as high cost of production, require high energy input and generation of toxic by-products. To overcome this, several biological methods are employed in the synthesis of nanoparticles. The biological methods are generally cost effective, nontoxic, and ecofriendly. This chapter focuses on the methods involved in algal-synthesized nanoparticles and its applications

    Artisanal mining versus sustainability of agricultural food supply chains: effects of the conflicts in Southern Zimbabwe

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    This article seeks to establish the social and environmental consequences of artisanal mining on economic sustainability of agricultural food supply chains in Zimbabwe. Following a descriptive research design, interviews were conducted with 36 farmers. Interviewees were purposively sampled from potential respondents in Southern Zimbabwe. Interview results were triangulated with data from published reports and newspaper articles. Data was analysed using NVivo application version 12 and presented in vignettes. The results of this study are useful to artisanal miners, farmers, and government. Recommendations for further studies are given. KEYWORDS: Artisanal mining farmers food supply chains Zimbabwe sustainabilit

    The effects of supply chain cooperation on humanitarian relief operations: A case of Cyclone Idai in Zimbabwe

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    Background: The increased frequency of occurrence and complexity of disasters, the world over, have called for increased cooperation amongst stakeholders to deliver humanitarian aid. Objectives: This study came as a result of the growing interest focussed on creating and implementing cooperation to facilitate management of supply chain-related activities in the humanitarian sector. This study therefore sought to gain a better understanding of the effectiveness of supply chain cooperation in aid delivery performance variables, specifically in the context of Cyclone Idai humanitarian relief operations in Zimbabwe. Method: A pragmatic research paradigm was adopted, where the researchers took a mixed approach informed by both quantitative and qualitative research tools. Results: Findings of this study show a significant and positive impact of humanitarian supply chain (HSC) cooperation in achieving output, resource and flexibility performance in the delivery of aid. These findings will change the shape of humanitarian response to have more cooperation amongst organisations rather than responding as single entities. Conclusion: This study will therefore contribute to how humanitarian organisations improve their approach to future disasters through cooperation in their supply chain activities. Theoretically, the study will show how supply chain cooperation is key to humanitarian responses, thus improving effectiveness of HSC when put into practice. Policymakers can use these findings to develop a standard framework of how humanitarian organisations should collectively respond to disasters. Keywords: cyclone; humanitarian logistics; relief operations; supply chain; supply chain cooperation

    Genetic Testing to Inform Epilepsy Treatment Management From an International Study of Clinical Practice

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    IMPORTANCE: It is currently unknown how often and in which ways a genetic diagnosis given to a patient with epilepsy is associated with clinical management and outcomes. OBJECTIVE: To evaluate how genetic diagnoses in patients with epilepsy are associated with clinical management and outcomes. DESIGN, SETTING, AND PARTICIPANTS: This was a retrospective cross-sectional study of patients referred for multigene panel testing between March 18, 2016, and August 3, 2020, with outcomes reported between May and November 2020. The study setting included a commercial genetic testing laboratory and multicenter clinical practices. Patients with epilepsy, regardless of sociodemographic features, who received a pathogenic/likely pathogenic (P/LP) variant were included in the study. Case report forms were completed by all health care professionals. EXPOSURES: Genetic test results. MAIN OUTCOMES AND MEASURES: Clinical management changes after a genetic diagnosis (ie, 1 P/LP variant in autosomal dominant and X-linked diseases; 2 P/LP variants in autosomal recessive diseases) and subsequent patient outcomes as reported by health care professionals on case report forms. RESULTS: Among 418 patients, median (IQR) age at the time of testing was 4 (1-10) years, with an age range of 0 to 52 years, and 53.8% (n = 225) were female individuals. The mean (SD) time from a genetic test order to case report form completion was 595 (368) days (range, 27-1673 days). A genetic diagnosis was associated with changes in clinical management for 208 patients (49.8%) and usually (81.7% of the time) within 3 months of receiving the result. The most common clinical management changes were the addition of a new medication (78 [21.7%]), the initiation of medication (51 [14.2%]), the referral of a patient to a specialist (48 [13.4%]), vigilance for subclinical or extraneurological disease features (46 [12.8%]), and the cessation of a medication (42 [11.7%]). Among 167 patients with follow-up clinical information available (mean [SD] time, 584 [365] days), 125 (74.9%) reported positive outcomes, 108 (64.7%) reported reduction or elimination of seizures, 37 (22.2%) had decreases in the severity of other clinical signs, and 11 (6.6%) had reduced medication adverse effects. A few patients reported worsening of outcomes, including a decline in their condition (20 [12.0%]), increased seizure frequency (6 [3.6%]), and adverse medication effects (3 [1.8%]). No clinical management changes were reported for 178 patients (42.6%). CONCLUSIONS AND RELEVANCE: Results of this cross-sectional study suggest that genetic testing of individuals with epilepsy may be materially associated with clinical decision-making and improved patient outcomes

    The moderating role of vendor managed inventory on the bullwhip effect in the COVID-19 pandemic

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    AbstractThe study sought to determine the role of vendor-managed inventory and form postponement in mitigating against the bullwhip effect in the bakery industry. The bullwhip effect is referred to as demand distortions along the upstream supply chain that is caused by variances between supply and demand. The bullwhip effect was conceptualized by its indicators that are overstocking, obsolescence, and inventory holding costs. A survey of conveniently chosen 100 bakeries was conducted in the city of Harare, the capital city of Zimbabwe. The informants for individual bakeries were competent bookkeepers or qualified accountants. A factorial MANOVA and follow-up ANOVAs using the Bonferroni method were conducted. The study indicated statistically significant main effects and interaction effects for all the factors and concluded that all the indicators of the bullwhip effect can be mitigated if bakery businesses pursued either or both of the vendor-management inventory and the form postponement strategies. The managerial implications of this study were that bakery businesses can avoid the consequences of the bullwhip effect through investing in plant and equipment that enables form postponement, and strengthen the widely practiced vendor-management strategy

    The impact of collaborative strategies on disaster risk reduction in Zimbabwe dairy supply chains in 2016

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    Disasters are on the increase globally with accompanying devastating effects on dairy supply chains. The devastating effects, caused by disasters on economies in various countries such as United States of America, Japan, Kenya, Uganda, Mozambique and Zimbabwe call for urgent sustainable mitigating measures in disaster risk reduction. These countries have experienced notable natural and man-made disasters in the past. The disasters negatively impacted the economies of both developed and developing countries, causing misery to people as hunger and poverty drastically increased. Zimbabwe’s dairy industry was not spared from these devastating effects as it was vulnerable to disasters such as droughts and cyclones. Disasters adversely affected supply chains in the country as evidenced by the closure of some dairy firms between the years 2000 and 2014. This article is set against the backdrop of declining output across all agricultural sectors in Zimbabwe, evident particularly in the dairy farming sector which has witnessed inadequate supply of raw milk and dairy products by local producers. The article assesses the impact of dairy organisations’ partnerships with government departments and non-governmental organisations in reducing disaster risks on the dairy supply chain cost efficiency. It also aims to show how partnerships can reduce disaster risks and weighs the benefits of reduced supply chain costs in improving the affordability of milk and milk products to the general public. The study employs a mixed-methods approach comprising structured questionnaires, administered to a sample of 92 respondents out of a randomly sampled population of 122 participants from dairy farming clusters across the country, with an 85% response rate. Key informants in the form of 18 dairy officers were purposively sampled for interviews throughout the dairy farming regions. The research findings will help government in the formulation of public policies for the dairy sector network in reducing disaster risks
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