42 research outputs found
Influence of creep on water pressure measured from borehole tests in the Meuse/Haute-Marne Callovo-Oxfordian argillites
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
ModĂ©lisation numĂ©rique de lâimpact dâun bloc rocheux sur un Ă©boulis. Analyse stochastique des coefficients de rĂ©flexion
De par les destructions et dĂ©gradations importantes quâelles occasionnent, les chutes de blocs isolĂ©s dans les rĂ©gions montagneuses constituent un risque naturel majeur. Sur le plan de la prĂ©vention, la simulation de la trajectoire de ces blocs en interaction avec les Ă©ventuels obstacles naturels du versant (terrain naturel, couverture forestiĂšre), Ă lâaide dâoutils appropriĂ©s, constitue une Ă©tape essentielle permettant de prĂ©senter une cartographie dâintensitĂ© du phĂ©nomĂšne redoutĂ©. Dans cette vaste problĂ©matique, lâarticle traite plus spĂ©cifiquement de lâĂ©tude de lâimpact dâun bloc rocheux sur un sol composĂ© dâĂ©boulis, dans lâobjectif dâĂ©tablir une loi de rĂ©flexion qui sera intĂ©grĂ©e Ă terme dans un code de trajectographie. Le caractĂšre fortement stochastique de cette loi a Ă©tĂ© clairement Ă©tabli. Dans le cas dâun impact normal Ă la surface du sol, une premiĂšre analyse a permis de montrer quâil existait une dĂ©pendance linĂ©aire entre la vitesse incidente et les vitesses rĂ©flĂ©chies normale, tangentielle, et de rotation ; de plus, il est apparu que le coefficient de rĂ©flexion normale suivait une distribution normale, alors que le coefficient de rĂ©flexion tangentielle Ă©tait plutĂŽt dĂ©crit par une loi BĂȘta. Une modĂ©lisation plus rĂ©aliste de la phase de contact entre le bloc et le sol contribue, en effet, Ă une Ă©valuation plus judicieuse des vitesses du bloc ainsi que de ses hauteurs de passage. Ce sont ces paramĂštres qui permettent de dĂ©finir les stratĂ©gies de protection les plus adaptĂ©es (localisation et dimensionnement)
Transient model of early stages in compartment fires
Peer reviewed: YesNRC publication: Ye
A framework for coupled hydro-mechanical continuous modelling of gap-graded granular soils subjected to suffusion
202310 bcchAccepted ManuscriptRGCOthersNational Institute for Industrial Environment and Risks of FrancePublishe
Hydro-mechanical modelling of landslides with a material instability criterion
International audienc