Image of the high school students towards mathematicians

Aim of this study is identify how high school students see mathematicians by the pictures they visualized. In accordance with this purpose phenomenology pattern which is one of the qualitative patterns was used as a research pattern. The study was carried out with 150 volunteered high school students. The data collection tool to be used in this study consists of four parts. The first part includes questions to determine demographic characteristics of students, second part include drawing box prepared to define images of students towards mathematicians and open ended questions towards describing drawing, third part includes the presented options to define the image sources towards mathematicians and the fourth part includes open-ended questions to determine famous mathematicians and reasons. The images that students draw about mathematicians were analyzed by the content analyses method. It is believed that the results from at the end of the study will be helpful to training of mathematics teacher

Student views with regard to probsol learning environment

The aim of this study is to assess learner views with regard to ProbSol learning environment prepared according to problem solving steps for the teaching of “applications related to equations and inequalities”. In line with this aim, the study was carried out with 15 volunteered 9th graders who are taught with ProbSol. The study is a case study, which is one of the qualitative research paradigms, and a semi-structured interview form with 8 open-ended questions developed by the researchers was used. Data obtained from semi-structured interview form were analyzed with content analysis method. In general, the views of the participants with regard to ProbSol environment were mostly positive

Assessment of instructional materials developed with flash software for the teaching of area applications in integral

Bu çalışmanın amacı, öğretim üyeleri, matematik öğretmenleri ve öğrencilerin “ İntegralde alan uygulamaları” konusunda Flash Animasyon Programı ile geliştirilen öğretim materyali hakkındaki görüşlerini değerlendirmektir. Bu araştırmada nitel araştırma yöntemlerinden durum çalışması yapılmıştır. Araştırma 4 öğretim üyesi, 5 matematik öğretmeni ve 4 öğrenci ile yürütülmüştür. Araştırmanın verileri 6 açık uçlu sorudan oluşan yarı yapılandırılmış görüşme formu ile toplanmıştır. Yarı yapılandırılmış görüşme formundan elde edilen veriler ise betimsel analiz yöntemiyle analiz edilmiştir. Araştırmanın sonucunda katılımcılar, hazırlanan materyalin içeriğinin “İntegralde alan uygulamaları” konusunun kazanımlarına uygun ve doğru olduğunu belirtmiştir. Materyalin teknik kalitesinin iyi olduğu ancak ses kapat ve durdur butonlarının da bulunması gerektiğini vurgulamıştır. Katılımcıların çoğu materyalin renk seçimi ve yazı büyüklüğünün ideal olduğu yani görsel tasarımının iyi olduğu görüşündedirler. Katılımcıların görüşleri incelendiğinde, geliştirilen öğretim materyalinin öğrenme-öğretme sürecinde kullanılabileceği sonucuna ulaşılmıştır.The aim of this study is to assess the opinions of faculty members, mathematic teachers and students with regard to instructional materials developed a case study, which is one of the qualitative research methods. The study group included 4 lecturers, 5 math teachers and 4 students. Data for the study was collected via a semi-structured interview composed of 6 open-ended questions. Data obtained via semi-structured interview form were analyzed with descriptive analysis method. As a result of the study, it was found that participants stated that the content of the al quality of the material was good but there of the opinion that color choice and font size were ideal and thus its visual design was good. When the views of participants were examined, it was concluded that the material can be used in the teaching-learning process

Assessment of ındıvıdualızed web based learnıng envıronment based on problem solvıng steps

Bu çalışmada, 9. sınıf matematik dersi müfredatında yer alan “Denklem ve Eşitsizlikler ile İlgili Uygulamalar” konusunun öğretimi için geliştirilen problem çözme basamaklarına dayalı bireyselleştirilmiş web tabanlı öğrenme ortamının öğrenmeye etkisi, öğretim programına uygunluğu ve tasarım açısından değerlendirilmesi hedeflenmiştir. Tasarlanan ortamın değerlendirilmesi için veri toplama aracı olarak beşli likert tipi 20 maddeden oluşan “ProbSol Öğrenme Ortamı Değerlendirme Ölçeği” kullanılmıştır. Bu ölçek yardımıyla, 121 Matematik öğretmeni tarafından ProbSol öğrenme ortamının öğrenmeye etkisi, öğretim programına uygunluğu ve tasarım açısından değerlendirilmesi sağlanmıştır. Değerlendirme ölçeğinden elde edilen veriler ışığında; geliştirilen ProbSol öğrenme ortamının öğrencilerin öğrenmeleri üzerinde olumlu yönde katkı sağlayacağı, ProbSol öğrenme ortamının içeriğinin Ortaöğretim Matematik Dersi Öğretim Programına uygun olduğu, bu öğrenme ortamının genel olarak tasarım ilkelerine uygun olarak tasarlandığı ve sistemin kullanımın kolay olduğu sonuçlarına ulaşılabilir. Bu değerlendirmeler ışığında gerekli düzenlemeler yapılarak ProbSol öğrenme ortamının gerçek sınıf ortamında kullanılabilir ve geçerli bir öğrenme ortamı olduğu sonucuna ulaşılmıştır.The aim of this study is to assess the individualized web based learning environment based on problem solving steps developed to teach the topic of “Applications with regard to equations and inequalities” in terms of impact on learning, appropriateness of the curriculum and design. “ProbSol learning environment assessment” scale, which included 20 likert type items, was used to collect data for the assessment of the medium designed. With the help of the scale, 121 Mathematics teachers assessed ProbSol learning environment. According to the data obtained from the scale, it was concluded that the ProbSol would have positive contribution to students’ learning, the content of ProbSol is suitable for secondary education Mathematics program, the design of this learning environment is compatible with overall design principles and the use of system is easy. Based on the results, it was concluded that with necessary amendments ProbSol can be used in real classroom environments

An analysis on the housing price channel: The case of BRICT

Abstract. The asset prices channel, as one of the transmission channels of monetary policy, refers to the process of changing aggregate demand level by affecting the asset prices of a change in the central bank's monetary policy decisions. There are 3 basic components of the asset price channels: stock price channel, housing price channel and exchange rate channel. In this study, the operation of the housing price channel is investigated by applying Panel VAR analysis. For this purpose, the data between 2009Q1-2017Q4 period for BRICT countries are analyzed and tested. The findings show that the housing price channel is operating in these countries. The study consists of three parts. In the first part, the operation of the housing price channel is explained. In the second part, the literature research and in the third section, the empirical analysis are emphasized.Keywords. Monetary transmission mechanism, Asset price channel, Stock price channel, Housing price channel.JEL. O18, R21, R30, R31

A Review of 2625 Isolated Hydrocele Cases in Children

Introduction: Inguinal hernias and hydroceles are the most frequently performed procedures in pediatric surgery departments. In this study, we aimed to define the spontaneous regression rate in different types of  hydroceles, the regression age, the timing of surgery, and the optimal treatment approaches for each hydrocele type in cases with isolated hydroceles in children.Material &Methods: This historical cohort study included 2625 patients which were admitted between January 2004 and December 2012. The hydroceles were classified as: ‘non-communicating hydroceles’, ‘communicating hydroceles’, ‘spermatic cord hydroceles’ and ‘abdomino-scrotal hydroceles’ (ASH). Patients were divided into two groups with regard to their ages at diagnosis as follows: those presenting in the newborn period and before 24 months of age (Younger– Group 1) and those presenting after 24 months of age (Older – Group 2). Determining the type of isolated hydrocele, the decision making for follow-up or surgery, and the follow-up period were conducted by 7 attending pediatric surgeons and 6 residents. Results: In Group 1, 93% of 1086 non-communicating hydroceles, 40% of 158 cord hydroceles, and 15% of 34 communicating hydroceles resolved during the follow-up, and the remaining patients with each type of hydrocele underwent surgery. In Group 2, 8.7% of 183 non-communicating hydroceles resolved during the follow-up.Conclusion: The primary treatment of patients with isolated hydrocele should be decided regarding the type of hydrocele, along with age at admission, and accordingly, conservative or surgical treatment should be considered

Ultrasound Guided Infraclavicular Block for Pain Control After Upper Extremity Surgery

Background: Opioids added to local anesthetics for peripheral nerve blocks may intensify analgesia and prolong analgesic and sensorial block duration. These agents may also cause potentiation and prolongation of motor block. Objective: This study compared the postoperative effects of 30 mL of 0.25% bupivacaine +50 mcg fentanyl and 30 mL of 0.25% bupivacaine + 100 mcg fentanyl solutions for the ultrasound-guided infraclavicular block in patients undergoing elbow and forearm surgery. Methods: In this randomized double-blind study, thirty-six patients with risk of ASA class I-III were randomly allocated into 2 randomized groups. Ultrasound-guided infraclavicular blocks with 30 mL of 0.25% bupivacaine + 50 mcg fentanyl for group 1 and 30 mL of 0.25% bupivacaine + 100 mcg fentanyl for group 2 were performed before patients emerged from general anesthesia. After surgery, pain levels at rest and during movement were evaluated using the 10-cm visual analog scale (VAS) at recovery room admission, at the 15th and 30th minutes in the recovery room, and at the 2nd, 6th, 12th and 24th hours postoperatively. Both morphine and rescue analgesic requirements were recorded. Sensorial and motor block durations, patient satisfaction, and complications related to the infraclavicular block were recorded. Results: In both groups, no significant difference in VAS pain scores, total morphine and total rescue analgesic requirements, duration of sensorial and motor block, or patient satisfaction were observed. None of the patients experienced any complications. Conclusion: The mixtures of 0.25% bupivacaine + 50 mcg fentanyl and 0.25% bupivacaine + 100 mcg fentanyl showed similar postoperative effects

Determination of Parasitic Contamination in Vegetables Collected from Local Markets in İzmir Province, Türkiye

Objective:Fresh vegetables are an important part of a healthy and nutrient-rich diet but the consumption of raw vegetables without proper washing is the main way for transmission of parasites. This study was aimed at determining the rate of parasitic contamination in prewashed fresh vegetables sold at randomly selected 10 retail markets which is the last step to reach the consumer in İzmir, Türkiye.Methods:A total of 80 samples selected from eight types of vegetables including tomato, spinach, lettuce, rocket, mint, parsley, dill, and cucumber were examined for parasitic agents microscopically by sedimentation method after washing samples with normal saline. Statistical analysis was performed using SPSS software version 20.0.Results:Protozoan cysts, helminth eggs, and larvae were detected in 21 (26.2%) of 80 samples from eight different vegetable species. Rhabditidiform larvae 18.7%, Blastocystis spp. 5%, Toxocara spp. 2.5%; Ascaris spp., Fasciola spp., Entamoeba histolytica/ Entamoeba dispar and hooked worms were found in 1.2%. Spinach and mint samples were contaminated with parasites significantly more than other fresh vegetable samples (p<0.008, odds ratio =80.0; p<0.017, odds ratio =46.6 respectively). Cruznema spp., a plant nematode, was found at the highest rate according to the results of culture, polymerase chain reaction and sequencing, respectively.Conclusion:In this study, the parasitic contamination was found in approximately one of the four vegetables sold in randomly selected markets in İzmir. These findings show that vegetables sold in local markets can cause parasitic infections if they are consumed without adequate washing and awareness should be raised on this issue. In addition, it was concluded that morphological examinations should be confirmed by molecular studies and sequencing as much as possible in order to avoid misdiagnosis of rhabditidiform larvae

Türkiye akademik CAR-T hücre (ISIKOK-19) klinik çalışması ön raporu: Ürün karakterizasyonu ve klinik uygulama sonuçları

Objective: Chimeric antigen receptor T (CAR-T) cell therapies have already made an impact on the treatment of B-cell malignancies. Although CAR-T cell therapies are promising, there are concerns about commercial products regarding their affordability and sustainability. In this preliminary study, the results of the first production and clinical data of an academic CAR-T cell (ISIKOK-19) trial in Turkey are presented. Materials and Methods: A pilot clinical trial (NCT04206943) designed to assess the safety and feasibility of ISIKOK-19 T-cell therapy for patients with relapsed and refractory CD19+ tumors was conducted and participating patients received ISIKOK-19 infusions between October 2019 and July 2021. The production data of the first 8 patients and the clinical outcome of 7 patients who received ISIKOK-19 cell infusions are presented in this study. Results: Nine patients were enrolled in the trial [5 with acute lymphoblastic leukemia (ALL) and 4 with non-Hodgkin lymphoma (NHL)], but only 7 patients could receive treatment. Two of the 3 participating ALL patients and 3 of the 4 NHL patients had complete/ partial response (overall response rate: 72%). Four patients (57%) had CAR-T-related toxicities (cytokine release syndrome, CAR-T-related encephalopathy syndrome, and pancytopenia). Two patients were unresponsive and had progressive disease following CAR-T therapy. Two patients with partial response had progressive disease during follow-up. Conclusion: Production efficacy and fulfillment of the criteria of quality control were satisfactory for academic production. Response rates and toxicity profiles were also acceptable for this heavily pretreated/refractory patient group. ISIKOK-19 cells appear to be a safe, economical, and efficient treatment option for CD19+ tumors. However, the findings of this study need to be supported by the currently ongoing ISIKOK-19 clinical trial.Amaç: Kimerik antijen reseptör T (CAR-T) hücre uygulamaları B-hücreli malignitelerin tedavisinde etkili olmaktadır. CAR-T hücre uygulamalarının sonuçları umut vaadedici olsa da, ticari CAR-T ürünlerinin yükek maliyetleri nedeniyle ulaşılabilirlik açısından ciddi sorunlar yaşanmaktadır. Bu ön raporda, Türkiye’deki ilk akademik CAR-T hücre çalışmasının üretim ve klinik uygulama sonuçları sunulmuştur. Gereç ve Yöntemler: Relaps refrakter CD 19+ hematolojik maligniteli hastalarda ISIKOK-19 T-hücre tedavisinin güvenliği ve etkinliğini değerlendirmek amacıyla yürütülen klinik çalışmaya (NCT04206943) Ekim 2019-Temmuz 2021 tarihleri arasındaki hastalar dahil edilmiştir. Bu raporda ilk 8 hastanın üretim bilgileriyle, ISIKOK-19 hücre infüzyonu yapılan 7 hastanın klinik sonuçları sunulmuştur. Bulgular: Çalışmaya toplam 9 hasta dahil edilmiştir (5 akut lenfoblastik lösemi [ALL] ve 4 non-hodgkin lenfoma [NHL]), ancak sadece 7 hastaya hücre infüzyonu yapılabilmiştir. Hücre infüzyonu alan 3 ALL hastasından 2’sinde ve 4 NHL hastasının 3’ünde tam/kısmi cevap gözlenmiştir (toplam yanıt oranı %72). Dört hastada (%57) CAR-T ilişkili toksisite (sitokin salınım sendromu, immün efektör hücre ilişkili nörotoksisite sendromu ve pansitopeni) tespit edilmiştir. İki hastada ise CAR-T hücre uygulaması sonrası cevapsızlık ve progresif hastalık izlenmiştir. Kısmi cevap veren hastalardan 2’sinde de takip sırasında progresif hastalık tespit edilmiştir. Sonuç: Akademik CAR-T üretimimiz, üretim etkinliği ve kalite kontrol kriterlerinin tam olarak karşılanması açısından tatmin edici sonuçlara sahiptir. Çalışmaya dahil edilen hastaların tedavi yükü hesaba katıldığında tedaviye cevap oranı ve toksisite profili açısından da sonuçlar kabul edilebilir düzeydedir. Bu sonuçlarla, ISIKOK-19 hücrelerinin güvenli, ekonomik ve etkili bir tedavi seçeneği olduğu düşünülebilir. Ancak bu ön sonuçların halen devam eden ISIKOK-19 klinik çalışmasıyla desteklenmesi beklenmektedir

The effect of ındividualized web based mathematics learning environment developed based on problem solving steps on the students' academic achievements

Bu çalışmada, 9. Sınıf matematik müfredatında yer alan “Denklem ve eşitsizlikler ile ilgili uygulamalar” konusunun öğretimi için problem çözme basamaklarına dayalı olarak tasarlanan bireyselleştirilmiş web tabanlı öğrenme ortamının öğrencilerin akademik başarılarına etkisinin incelenmesi amaçlanmıştır. Bu amaç doğrultusunda, 137 9. sınıf öğrencisi ile yürütülen bu çalışmada kontrol gruplu ön test ve son test araştırma deseni kullanılmıştır. Araştırmanın verileri güvenirlik katsayısı 0,742 olan “Başarı testi” ile toplanmıştır. Başarı testinden elde edilen veriler istatistiksel olarak analiz edilmiştir. Araştırmanın sonucunda deney ve kontrol grubu öğrencilerinin son-test başarı puanları arasında istatistiksel olarak anlamlı bir fark olduğu belirlenmiştir. Buradan genel olarak ProbSol öğrenme ortamı ile bireysel özelliklerine uygun öğrenim gören öğrencilerin geleneksel yöntem ile öğrenim gören öğrencilere göre daha başarılı olduğu sonucuna ulaşılabilmektedirIn this study, it is aimed to investigate the effect of individualized web based mathematics learning environment developed based on problem solving steps on the students' academic achievements in teaching “Applications related to equations and inequalities” subject in mathematics curriculum of 9th grade. For this purpose, pre-test and post-test research design with control group was used in this study which was carried out with 137 students at 9th grade. The data of the study were collected by the "achievement test" which had a reliability coefficient of 0.742. The data obtained from the achievement test were analyzed statistically. As a result of the study, it was determined that there was a statistically significant difference between the post-test achievement scores of the experimental and control group students. It can be concluded that the students trained in ProbSol learning environment with learning environment with individual characteristics are more successful than students trained with traditional methods