CHARGING AND DETECTION OF MESOSPHERIC DUST WITH INSTRUMENT SPID ON G-CHASER ROCKET

The Smoke Particle Impact Detector (SPID) was flown on the G-Chaser student rocket that was launched from Andøya on 13 January 2019. SPID is a Faraday cup instrument with applied bias voltages to deflect the ambient plasma and a target area inside the probe designed to measure the dust particles by charge detection. The charging process of the dust particles in the detector is important for interpretation of the measurements and the influence of the charging models is discussed. Preliminary analysis of the SPID observations shows that ambient plasma and sunlight had an influence on the signals; further analysis is needed to retrieve information on impacting dust from the data

Fibroblast miR-210 overexpression is independently associated with clinical failure in Prostate Cancer – a multicenter (in situ hybridization) study

There is a need for better prognostication in prostate cancer (PC). “The micromanager of hypoxia”, microRNA-210 (miR-210) is directly linked to hypoxia, is overexpressed in PC and has been implied in tumor cell-fibroblast crosstalk. We investigated the prognostic impact of miR-210 in tumor cells and fibroblasts in PC. Tumor and stromal samples from a multicenter PC cohort of 535 prostatectomy patients were inserted into tissue microarrays. To investigate the expression of miR-210, we used in situ hybridization and two pathologists semiquantitatively scored its expression. Overexpression of miR-210 in tumor cells was not associated to biochemical failure-free survival (BFFS, p=0.85) or clinical failure-free survival (CFFS, p=0.09). However, overexpression of miR-210 in fibroblasts was significantly associated to a poor CFFS (p=0.001), but not BFFS (p=0.232). This feature was validated in both cohorts. Overexpression of miR-210 was independently associated with a reduced CFFS (HR=2.76, CI 95% 1.25–6.09, p=0.012). Overexpression of miR-210 in fibroblasts is independently associated with a poor CFFS. This highlights the importance of fibroblasts and cellular compartment crosstalk in PC. miR-210 is a candidate prognostic marker and potential therapeutic target in PC

CHARGING AND DETECTION OF MESOSPHERIC DUST WITH INSTRUMENT SPID ON G-CHASER ROCKET

The Smoke Particle Impact Detector (SPID) was flown on the G-Chaser student rocket that was launched from Andøya on 13 January 2019. SPID is a Faraday cup instrument with applied bias voltages to deflect the ambient plasma and a target area inside the probe designed to measure the dust particles by charge detection. The charging process of the dust particles in the detector is important for interpretation of the measurements and the influence of the charging models is discussed. Preliminary analysis of the SPID observations shows that ambient plasma and sunlight had an influence on the signals; further analysis is needed to retrieve information on impacting dust from the data

Observation of mesospheric dust and ionospheric conditions during the G-chaser rocket campaign

Paper at 24th ESA Symposium on European Rocket and Balloon Programmes and Related Research, Essen, Germany, 16-20 June 2019. Conference home page.SPID, Smoke Particle Impact Detector, is a Faraday cup detector designed to measure nanometer-sized meteoric smoke particles during rocket flights. We report measurements made with SPID during the G-Chaser student rocket campaign 13 January 2019 and describe the design of the SPID instruments. Model calculations of dust trajectories within the detector result in an effective crosssection of 0.97 for particles larger than 0.5 nm at 60 km. Data analysis indicates that in order to generate the measured current, the number densities must be ∼ 1010m−3 or higher at 60 km. During the campaign the ground systems MAARSY and EISCAT were operating. These ground measurements showed smooth ionospheric conditions with weak precipitation down to 90 km. As a secondary goal of the campaign we wanted to investigate the possible connection between PMWE and MSPs. On the day of the launch there was no sign of PMWE and no conclusions can be drawn at this point

Observation of mesospheric dust and ionospheric conditions during the G-chaser rocket campaign

SPID, Smoke Particle Impact Detector, is a Faraday cup detector designed to measure nanometer-sized meteoric smoke particles during rocket flights. We report measurements made with SPID during the G-Chaser student rocket campaign 13 January 2019 and describe the design of the SPID instruments. Model calculations of dust trajectories within the detector result in an effective crosssection of 0.97 for particles larger than 0.5 nm at 60 km. Data analysis indicates that in order to generate the measured current, the number densities must be ∼ 1010m−3 or higher at 60 km. During the campaign the ground systems MAARSY and EISCAT were operating. These ground measurements showed smooth ionospheric conditions with weak precipitation down to 90 km. As a secondary goal of the campaign we wanted to investigate the possible connection between PMWE and MSPs. On the day of the launch there was no sign of PMWE and no conclusions can be drawn at this point