1,383 research outputs found
ANANAS - A Framework For Analyzing Android Applications
Android is an open software platform for mobile devices with a large market
share in the smartphone sector. The openness of the system as well as its wide
adoption lead to an increasing amount of malware developed for this platform.
ANANAS is an expandable and modular framework for analyzing Android
applications. It takes care of common needs for dynamic malware analysis and
provides an interface for the development of plugins. Adaptability and
expandability have been main design goals during the development process. An
abstraction layer for simple user interaction and phone event simulation is
also part of the framework. It allows an analyst to script the required user
simulation or phone events on demand or adjust the simulation to his needs. Six
plugins have been developed for ANANAS. They represent well known techniques
for malware analysis, such as system call hooking and network traffic analysis.
The focus clearly lies on dynamic analysis, as five of the six plugins are
dynamic analysis methods.Comment: Paper accepted at First Int. Workshop on Emerging Cyberthreats and
Countermeasures ECTCM 201
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CpCo(III) Precatalysts for [2+2+2] Cycloadditions
Catalysts applied in cobalt-catalyzed cyclotrimerizations reactions in general rely on the use of Co(I) precatalysts or the in situ generation of Co(I) catalysts from Co(II) sources by reduction in the presence of steering ligands, often by addition of less noble metals. In this paper, we report the synthesis and properties of novel stable CpCo(III) complexes as precatalysts and their exemplary evaluation for application in catalytic [2+2+2] cycloadditions. The role of phosphite neutral ligands, as well as iodide and cyanide as anionic ligands, on the reactivity of the complexes was evaluated. A modified one-pot approach to the synthesis of Cp ring-functionalized Cp’Co(III) complexes was developed. The investigations demonstrated that CpCo(III) complexes can be directly applied as catalysts in catalytic cyclotrimerizations of triynes without reducing agents as additives. © 2021 by the authors. Licensee MDPI, Basel, Switzerland
Ausstieg aus der ÖPUL-Maßnahme biologische Wirtschaftsweise
The end of the first five-year contract period of the Austrian Agri-environmental Program (ÖPUL) caused a number of farmers to opt out of the measure organic farming at the end of 1999 and in the following years. A survey was made in 2003 to explore the reasons for reverting to conventional farming. The three most important reasons were the high cost of organic grain for feed, the lack of price premia for organic products (mostly beef and milk) and the frequency of changes in organic standards. Most respondents operate grassland-based dairy farms in Alpine regions. The average size of the farms opting out was 12,0 ha
3D Tunnel Inspection with Photogrammetric and Hybrid Systems
The trend in tunnel assessment is towards comprehensive 3D measurement, either based on high quality digital imagery (photogrammetric systems) or the combination of laser and photo systems (hybrid systems). With digital 3D data, quantification and categorization of damage to the tunnel surface as well as the determination of thickness or volumes of layers (e.g. shotcrete) can performed in a comprehensive, fast and economic way.
The faster such tunnel assessment can be executed on site, the lower are the tunnel block times and environmental impairments related to the building measures. The costs for the operating companies can be significantly reduced as well as the personnel efforts and risks of accidents. Furthermore, tunnel safety is increased due to faster test cycles which result in a more comprehensive overall monitoring.
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Protocol TOP-Study (tacrolimus organ perfusion): a prospective randomized multicenter trial to reduce ischemia reperfusion injury in transplantation of marginal liver grafts with an "ex vivo" tacrolimus perfusion
Background: Critical organ shortage results in the utilization of extended donor criteria (EDC) liver grafts. These marginal liver grafts are prone to increased ischemia reperfusion injury (IRI) which may contribute to deteriorated graft function and survival. Experimental data have shown that the calcineurin inhibitor tacrolimus exerts protective effects on hepatic IRI when applied intravenously or directly as a hepatic rinse. Therefore, the aim of the present study is to examine the effects of an ex vivo tacrolimus perfusion on IRI in transplantation of EDC liver grafts.
Methods/Design: The TOP-Study (tacrolimus organ perfusion) is a randomized multicenter trial comparing the ex vivo tacrolimus perfusion of marginal liver grafts with placebo. We hypothesize that a tacrolimus rinse reduces IRI, potentially improving organ survival following transplantation of EDC livers. The study includes livers with two or more EDC, according to Eurotransplant International Foundation’s definition of EDC livers. Prior to implantation, livers randomized to the treatment group are rinsed with tacrolimus at a concentration of 20 ng/ml in 1000 ml Custodiol solution and in the placebo group with Custodiol alone. The primary endpoint is the maximum serum alanine transamninase (ALT) level within the first 48 hours after surgery; however, the study design also includes a 1-year observation period following transplantation. The TOP-Study is an investigator-initiated trial sponsored by the University of Munich Hospital. Seven other German transplant centers are participating (Berlin, Frankfurt, Heidelberg, Mainz, Münster, Regensburg, Tübingen) and aim to include a total of 86 patients.
Discussion: Tacrolimus organ perfusion represents a promising strategy to reduce hepatic IRI following the transplantation of marginal liver grafts. This treatment may help to improve the function of EDC grafts and therefore safely expand the donor pool in light of critical organ shortage.
Trial register: EudraCT number: 2010-021333-31, ClinicalTrials.gov identifier: NCT0156409
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