The supersymmetric Higgs sector and B-Bbar mixing for large tan beta

We match the Higgs sector of the most general flavour breaking and CP violating minimal supersymmetric standard model (MSSM) onto a generic two-Higgs-doublet model, paying special attention to the definition of tan beta in the effective theory. In particular no tan beta-enhanced loop corrections appear in the relation to tan beta defined in the DRbar scheme in the MSSM. The corrections to the Higgs-mediated flavour-changing amplitudes which result from this matching are especially relevant for the B_d and B_s mass differences dM_s,d for minimal flavour violation, where the superficially leading contribution vanishes. We give a symmetry argument to explain this cancellation and perform a systematic study of all Higgs-mediated effects, including Higgs loops. The corrections to dM_s are at most 7% for mu>0 and M_A < 600 if constraints from other observables are taken into account. For mu<0 they can be larger, but are always less than about 20%. Contrary to recent claims we do not find numerically large contributions here, nor do we find any tan beta-enhanced contributions from loop corrections to the Higgs potential in B^+ -> tau^+ nu or B -> X_s gamma. We further update supersymmetric loop corrections to the Yukawa couplings, where we include all possible CP-violating phases and correct errors in the literature. The possible presence of CP-violating phases generated by Higgs exchange diagrams is briefly discussed as well. Finally we provide improved values for the bag factors P^VLL_1, P^LR_2, and P^SLL_1 at the electroweak scale.Comment: 61 page

A priori convergence estimates for a rough Poisson-Dirichlet problem with natural vertical boundary conditions

Stents are medical devices designed to modify blood flow in aneurysm sacs, in order to prevent their rupture. Some of them can be considered as a locally periodic rough boundary. In order to approximate blood flow in arteries and vessels of the cardio-vascular system containing stents, we use multi-scale techniques to construct boundary layers and wall laws. Simplifying the flow we turn to consider a 2-dimensional Poisson problem that conserves essential features related to the rough boundary. Then, we investigate convergence of boundary layer approximations and the corresponding wall laws in the case of Neumann type boundary conditions at the inlet and outlet parts of the domain. The difficulty comes from the fact that correctors, for the boundary layers near the rough surface, may introduce error terms on the other portions of the boundary. In order to correct these spurious oscillations, we introduce a vertical boundary layer. Trough a careful study of its behavior, we prove rigorously decay estimates. We then construct complete boundary layers that respect the macroscopic boundary conditions. We also derive error estimates in terms of the roughness size epsilon either for the full boundary layer approximation and for the corresponding averaged wall law.Comment: Dedicated to Professor Giovanni Paolo Galdi 60' Birthda

Next-to-leading order QCD corrections to Z boson pair production via vector-boson fusion

Vector-boson fusion processes are an important tool for the study of electroweak symmetry breaking at hadron colliders, since they allow to distinguish a light Higgs boson scenario from strong weak boson scattering. We here consider the channels WW->ZZ and ZZ->ZZ as part of electroweak Z boson pair production in association with two tagging jets. We present the calculation of the NLO QCD corrections to the cross sections for p p -> e+ e- mu+ mu- + 2 jets and p p -> e+ e- nu_mu nubar_mu + 2 jets via vector-boson fusion at order alpha_s alpha^6, which is performed in the form a NLO parton-level Monte Carlo program. The corrections to the integrated cross sections are found to be modest, while the shapes of some kinematical distributions change appreciably at NLO. Residual scale uncertainties typically are at the few percent level.Comment: 12 pages, 4 figure

Challenges to the development of antigen-specific breast cancer vaccines

Continued progress in the development of antigen-specific breast cancer vaccines depends on the identification of appropriate target antigens, the establishment of effective immunization strategies, and the ability to circumvent immune escape mechanisms. Methods such as T cell epitope cloning and serological expression cloning (SEREX) have led to the identification of a number target antigens expressed in breast cancer. Improved immunization strategies, such as using dendritic cells to present tumor-associated antigens to T lymphocytes, have been shown to induce antigen-specific T cell responses in vivo and, in some cases, objective clinical responses. An outcome of successful tumor immunity is the evolution of antigen-loss tumor variants. The development of a polyvalent breast cancer vaccine, directed against a panel of tumor-associated antigens, may counteract this form of immune escape

New insights into the dynamics of the glutathione-ascorbate redox system of plants

The Hallilwell-Asada-Foyer redox cascade (HAF) is viewed as a H2O2 detoxifying system with a great variety of responses against environmental changes. The functional consequences of these responses are interpreted intuitively because a systemic analysis of the inherent dynamic potential of the HAF is lacking. With the help of numerical modelling we show that in wheat roots parameter patterns are established which result in homeostatic states of HAF over a vast range of environmental changes. The reduced fractions glutathione (GSH) and ascorbate (ASC) remain on high levels even during dramatic changes in the enzyme activity ratios of glutathione reductase, dehydroascorbate reductase and ascorbat peroxidase. Necessarily their oxidised counterparts dithioglutathione (GSSG) and dehydroascorbate (DHA) stay in these buffered regions on very low concentration levels. Our modelling shows that redox ratios GSH/GSSG and ASC/DHA can be modified additionally via changes in NADPH/H2O2 ratios. Thus, the redox states of GSH and ASC can not simply be regarded as indicators for oxidative stress with respect to H2O2 levels. The involvement of the redox variables in other redox processes than the HAF reaction (redox proteome) and / or their utilisation in metabolism (protein modification, detoxification of xenobiotics) are viewed to cause system relaxations of the redox variables. The re-establishment of their homeostatic ratios follow time courses which are redox moiety specific and are balanced according to the existing parameter patterns. Despite of its detoxification function the HAF balances the glutathione / ascorbate redox state in cells according to the prevailing physiological conditions

Improving Monolithic Perovskite Silicon Tandem Solar Cells From an Optical Viewpoint

Perovskite silicon tandem solar cells are the most promising concept for a future photovoltaic technology. We report on recent progress from an optical viewpoint and disucss how we achieved more than 25 device efficienc

Effect of polarized gluon distribution on spin asymmetries for neutral and charged pion production

A longitudinal double spin asymmetry for \pi^0 production has been measured by the PHENIX collaboration. The asymmetry is sensitive to the polarized gluon distribution and is indicated to be positive by theoretical predictions. We study a correlation between behavior of the asymmetry and polarized gluon distribution in neutral and charged pion production at RHIC.Comment: 7 pages, 5 eps figures, section added, typos corrected. to be published in PR

Internal kinematics of spiral galaxies in distant clusters III. Velocity fields from FORS2/MXU spectroscopy

(Abridged) We study the impact of cluster environment on the evolution of spiral galaxies by examining their structure and kinematics. Rather than two-dimensional rotation curves, we observe complete velocity fields by placing three adjacent and parallel FORS2 MXU slits on each object, yielding several emission and absorption lines. The gas velocity fields are reconstructed and decomposed into circular rotation and irregular motions using kinemetry. To quantify irregularities in the gas kinematics, we define three parameters: sigma_{PA} (standard deviation of the kinematic position angle), Delta phi (the average misalignment between kinematic and photometric position angles) and k_{3,5} (squared sum of the higher order Fourier terms). Using local, undistorted galaxies from SINGS, these can be used to establish the regularity of the gas velocity fields. Here we present the analysis of 22 distant galaxies in the MS0451.6-0305 field with 11 members at z=0.54. In this sample we find both field (4 out of 8) and cluster (3 out of 4) galaxies with velocity fields that are both irregular and asymmetric. We show that these fractions are underestimates of the actual number of galaxies with irregular velocity fields. The values of the (ir)regularity parameters for cluster galaxies are not very different from those of the field galaxies, implying that there are isolated field galaxies that are as distorted as the cluster members. None of the deviations in our small sample correlate with photometric/structural properties like luminosity or disk scale length in a significant way. Our 3D-spectroscopic method successfully maps the velocity field of distant galaxies, enabling the importance and efficiency of cluster specific interactions to be assessed quantitatively.Comment: accepted for publication in A&A, high resolution version available at http://www.astro.rug.nl/~kutdemir/papers