Foldable conduit Patent

Foldable conduit capable of springing back as self erecting structural membe

Feshbach Resonance Cooling of Trapped Atom Pairs

Spectroscopic studies of few-body systems at ultracold temperatures provide valuable information that often cannot be extracted in a hot environment. Considering a pair of atoms, we propose a cooling mechanism that makes use of a scattering Feshbach resonance. Application of a series of time-dependent magnetic field ramps results in the situation in which either zero, one, or two atoms remain trapped. If two atoms remain in the trap after the field ramps are completed, then they have been cooled. Application of the proposed cooling mechanism to optical traps or lattices is considered.Comment: 5 pages, 3 figures; v.2: major conceptual change

A QTL for osteoporosis detected in an F2 population derived from White Leghorn chicken lines divergently selected for bone index

Osteoporosis, resulting from progressive loss of structural bone during the period of egg-laying in hens, is associated with an increased susceptibility to bone breakage. To study the genetic basis of bone strength, an F cross was produced from lines of hens that had been divergently selected for bone index from a commercial pedigreed White Leghorn population. Quantitative trait loci (QTL) affecting the bone index and component traits of the index (tibiotarsal and humeral strength and keel radiographic density) were mapped using phenotypic data from 372 F individuals in 32 F families. Genotypes for 136 microsatellite markers in 27 linkage groups covering ∼80% of the genome were analysed for association with phenotypes using within-family regression analyses. There was one significant QTL on chromosome 1 for bone index and the component traits of tibiotarsal and humeral breaking strength. Additive effects for tibiotarsal breaking strength represented 34% of the trait standard deviation and 7.6% of the phenotypic variance of the trait. These QTL for bone quality in poultry are directly relevant to commercial populations

Atom-Molecule Laser Fed by Stimulated Three-Body Recombination

Using three-body recombination as the underlying process, we propose a method of coherently driving an atomic Bose-Einstein condensate (BEC) into a molecular BEC. Superradiant-like stimulation favors atom-to-molecule transitions when two atomic BECs collide at a resonant kinetic energy, the result being two molecular BEC clouds moving with well defined velocities. Potential applications include the construction of a molecule laser.Comment: 4 pgs, 3 figs, RevTeX4, submitted to PRL; Corrected numerical example

Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity

Although expanded polyglutamine (polyQ) repeats are inherently toxic, causing at least nine neurodegenerative diseases, the protein context determines which neurons are affected. The polyQ expansion that causes Huntington's disease (HD) is in the first exon (HDx-1) of huntingtin (Htt). However, other parts of the protein, including the 17 N-terminal amino acids and two proline (polyP) repeat domains, regulate the toxicity of mutant Htt. The role of the P-rich domain that is flanked by the polyP domains has not been explored. Using highly specific intracellular antibodies (intrabodies), we tested various epitopes for their roles in HDx-1 toxicity, aggregation, localization, and turnover. Three domains in the P-rich region (PRR) of HDx-1 are defined by intrabodies: MW7 binds the two polyP domains, and Happ1 and Happ3, two new intrabodies, bind the unique, P-rich epitope located between the two polyP epitopes. We find that the PRR-binding intrabodies, as well as VL12.3, which binds the N-terminal 17 aa, decrease the toxicity and aggregation of HDx-1, but they do so by different mechanisms. The PRR-binding intrabodies have no effect on Htt localization, but they cause a significant increase in the turnover rate of mutant Htt, which VL12.3 does not change. In contrast, expression of VL12.3 increases nuclear Htt. We propose that the PRR of mutant Htt regulates its stability, and that compromising this pathogenic epitope by intrabody binding represents a novel therapeutic strategy for treating HD. We also note that intrabody binding represents a powerful tool for determining the function of protein epitopes in living cells

Limiting the grain ration for fattening cattle

During the past few years, the Iowa cattle feeder has been confronted with the big problem of determining how much corn grain to feed fattening cattle with corn silage allowed in conjunction with linseed oil meal as the supplement and a leguminous hay, such as alfalfa, as the dry roughage. Should the cattle be full-fed or limited-fed ? How limited should the grain ration be? If full-fed, how should the grain be given the cattle, by hand-fed or self-fed methods? Can all of the silage be replaced, economically, with alfalfa from the roughage standpoint? Should the same methods be employed for feeding from 150 to 160 days as for 120 days

Avatars:the other side of Proteus's mirror : a study into avatar choice regarding perception

The trend for online interactions, can be regarded as being ‘anti-so-cially social’, meaning that a great deal of time is spent playing, working and socializing with the internet serving as the communication conduit. Within that Virtual Social Environment very deep relationships are formed and maintained without the parties ever having met each other face-to-face. Raising the question how much does the physical appearance of an avatar influence the perception of the person behind it? Are relationships informed by appearance even in the vir-tual world and what implications does that have for second language acquisition? This paper leads to a small-scale research project where a selection of avatars with various racially identifiable characteristics were used to identify which av-atars a second language speaker would feel more at ease interacting with in the target language. The resultant research aims to test three hypotheses regarding preferred avatar choice for second language users based solely on perceptions