1,267 research outputs found
Book review: Conducting for a new era, by Edwin Roxburgh
Book review of: Conducting for a new era, by Edwin Roxburgh.Publisher PD
On-chip generation of heralded photon-number states
Beyond the use of genuine monolithic integrated optical platforms, we report
here a hybrid strategy enabling on-chip generation of configurable heralded
two-photon states. More specifically, we combine two different fabrication
techniques, \textit{i.e.}, non-linear waveguides on lithium niobate for
efficient photon-pair generation and femtosecond-laser-direct-written
waveguides on glass for photon manipulation. Through real-time device
manipulation capabilities, a variety of path-coded heralded two-photon states
can be produced, ranging from product to entangled states. Those states are
engineered with high levels of purity, assessed by fidelities of 99.58\%
and 95.08\%, respectively, obtained via quantum interferometric
measurements. Our strategy therefore stands as a milestone for further
exploiting entanglement-based protocols, relying on engineered quantum states,
and enabled by scalable and compatible photonic circuits
Defying distance, ameliorating access : school education for remote Australian students
Peer reviewedPublisher PD
Navigating the New Competition Law Frontier: Reviewing Global Antitrust Approaches to Technology Platforms
Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity.
Glycogen and lipids are major storage forms of energy that are tightly regulated by hormones and metabolic signals. We demonstrate that feeding mice a high-fat diet (HFD) increases hepatic glycogen due to increased expression of the glycogenic scaffolding protein PTG/R5. PTG promoter activity was increased and glycogen levels were augmented in mice and cells after activation of the mechanistic target of rapamycin complex 1 (mTORC1) and its downstream target SREBP1. Deletion of the PTG gene in mice prevented HFD-induced hepatic glycogen accumulation. Of note, PTG deletion also blocked hepatic steatosis in HFD-fed mice and reduced the expression of numerous lipogenic genes. Additionally, PTG deletion reduced fasting glucose and insulin levels in obese mice while improving insulin sensitivity, a result of reduced hepatic glucose output. This metabolic crosstalk was due to decreased mTORC1 and SREBP activity in PTG knockout mice or knockdown cells, suggesting a positive feedback loop in which once accumulated, glycogen stimulates the mTORC1/SREBP1 pathway to shift energy storage to lipogenesis. Together, these data reveal a previously unappreciated broad role for glycogen in the control of energy homeostasis
A Catalog and Atlas of Cataclysmic Variables: The Final Edition
The Catalog and Atlas of Cataclysmic Variables has been a staple of the CV
community for over 10 years. The catalog has grown from 751 CVs in 1993 to 1600
CVs at present. The catalog became a ``living'' edition in 2001, and its
contents have been continually updated since that time. Effective 27 January
2006, the catalog will transition to an archival site, with no further updates
to its contents. While it is antipicated that the site will remain active, we
present the complete contents of the site as a precaution against a loss of the
on-line data.Comment: 8 pages, including 6 table
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