Photoactive Polyoxometalate/DASA Covalent Hybrids for Photopolymerization in the Visible Range

International audienc

Studies of the Effectiveness of Bisphosphonate and Vanadium-Bisphosphonate Compounds In Vitro

Leishmaniasis is a disease that is a significant problem for people, especially in tropical regions of the world. Current drug therapies to treat the disease are expensive, not very effective, and/or of significant side effects. A series of alkyl bisphosphonate compounds and one amino bisphosphonate compound, as well as alendronate and zoledronate, were tested as potential agents against Leishmania tarentolae. Also, two polyoxometalates (POMs) with nitrogen-containing bisphosphonate ligands, vanadium/alendronate (V5(Ale)2) and vanadium/zoledronate (V3(Zol)3), were tested against L. tarentolae and compared to the results of the alendronate and zoledronate ligands alone. Of the compounds evaluated in this study, the V5(Ale)2 and V3(Zol)3 complexes were most effective in inhibiting the growth of L. tarentolae. The V5(Ale)2 complex had a larger impact on cell growth than either alendronate or orthovanadate alone, whereas zoledronate itself has a significant effect on cell growth, which may contribute to the activity of the V3(Zol)3 complex

Light effect on POM@MOF materials

National audienc

Porphyrin-based metal-organic frameworks: from synthesis to characterization and applications in photocatalysis

National audienc

Matériaux à base de polyoxométallates : des nanoparticules NP@POMs aux composites POM@MOFs

International audienc

Optical and Photocatalytic Properties of Polyoxometalates-based Materials Ranging from Simple Assemblies to Polyoxometalates@Metal-Organic-Frameworks Composites

International audienc