The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful?

The measurement of B-type natriuretic peptide (BNP) is recommended for the diagnosis of decompensated heart failure, the prognosis of chronic heart failure is worse if BNP is increased and studies suggest that BNP is useful to guide therapy. A study by Di Somma and colleagues adds to the body of evidence showing that patients with a marked decrease in BNP concentrations during their hospital admission are less likely to be readmitted with a further adverse cardiac event than patients in whom BNP fails to decrease. However, the wider interpretation of BNP concentrations in critically ill patients with other conditions remains uncertain

Sharing storage using dirty vectors

Consider a computation F with n inputs (independent variables) and m outputs (dependent variables) and suppose that we wish to evaluate the Jacobian of F. Automatic differentiation commonly performs this evaluation by associating vector storage either with the program variables (in the case of forward-mode automatic differentiation) or with the adjoint variables (in the case of reverse). Each vector component contains a partial derivative with respect to an independent variable, or a partial derivative of a dependent variable, respectively. The vectors may be full vectors, or they may be dynamically managed sparse data structures. In either case, many of these vectors will be scalar multiples of one another. For example, any intermediate variable produced by a unary operation in the forward mode will have a derivative vector that is a multiple of the derivative for the argument. Any computational graph node that is read just once during its lifetime will have an adjoint vector that is a multiple of the adjoint of the node that reads it. It is frequently wasteful to perform component multiplications explicitly. A scalar multiple of another vector can be replaced by a single multiplicative "scale factor" together with a pointer to the other vector. Automated use of this "dirty vector" technique can save considerable memory management overhead and dramatically reduce the number of floating-point operations required. In particular, dirty vectors often allow shared threads of computation to be reverse-accumulated cheaply. The mechanism permits a number of generalizations, some of which give efficient techniques for preaccumulation

Coating thickness and elastic modulus measurement using ultrasonic bulk wave resonance

Measurement of the resonant through thickness ultrasonic modes of a homogeneous plate using a fast Fourier transform of the temporal data can be used to calculate plate thickness very accurately. We describe an extension of this principle to two-layer systems, examining a thin coating on a substrate of known properties. The resonant behavior of these systems is predicted and we explain how this approach is used to measure coating thickness and elastic modulus. Noncontact electromagnetic acoustic transducers are used for ultrasonic measurement, as they do not significantly affect the resonant response of the system, unlike alternative contact transducers

The US economy from 1992 to 1998: historical and decomposition simulations with the USAGE model

USAGE is a 500 industry dynamic computable general equilibrium model of the US economy being developed at Monash University in collaboration with the US International Trade Commission. In common with the MONASH model of Australia, USAGE is designed for four modes of analysis: Historical, where we estimate changes in technology and consumer preferences; Decomposition, where we explain periods of economic history in terms of driving factors such as changes in technology and consumer preferences; Forecast, where we derive basecase forecasts for industries, occupations and regions that are consistent with trends from historical simulations and with available expert opinions; and Policy, where we derive deviations from basecase forecast paths caused by assumed policies. This paper reports our first set of historical and decomposition results. The historical results quantify several aspects of technical change in US industries for the period 1992 to 1998 including: intermediate-input-saving technical change; primary-factor-saving technical change; labor-capital bias in technical change; and import- domestic bias in technical change. The historical results also quantify shifts in consumer preferences between commodities. The decomposition results are applied in illustrative analyses of growth in US international trade between 1992 and 1998 and of growth in the US steel industry for this period.

Atmospheric effects on remote sensing of non-uniform temperature sources

The effects are considered of an absorbing, emitting, and scattering atmosphere upon the remote sensing of surface areas having non-uniform intensity. These atmospheric effects may be significant in determination, by remote sensing, of non-uniform surface temperature distributions, and the results of the investigation are applicable in such cases. Analytical methods and a digital computational program are presented, expressing the results in terms of contrast and contrast transmittance between two adjacent emitting areas having unequal intensities, in the presence of a additional disturbing emitters. In the computational procedure, emitting areas are replaced by point-source emitters, each assigned and effective intensity based upon the intensity of the area it replaces. Absorbing, emitting, and scattering behavior of the atmosphere may be specified in the computational procedure either by means of analytical atmospheric models or by means of calibrating ground level emitters

Classical String in Curved Backgrounds

The Mathisson-Papapetrou method is originally used for derivation of the particle world line equation from the covariant conservation of its stress-energy tensor. We generalize this method to extended objects, such as a string. Without specifying the type of matter the string is made of, we obtain both the equations of motion and boundary conditions of the string. The world sheet equations turn out to be more general than the familiar minimal surface equations. In particular, they depend on the internal structure of the string. The relevant cases are classified by examining canonical forms of the effective 2-dimensional stress-energy tensor. The case of homogeneously distributed matter with the tension that equals its mass density is shown to define the familiar Nambu-Goto dynamics. The other three cases include physically relevant massive and massless strings, and unphysical tahyonic strings.Comment: 12 pages, REVTeX 4. Added a note and one referenc

Spinning branes in Riemann-Cartan spacetime

We use the conservation law of the stress-energy and spin tensors to study the motion of massive brane-like objects in Riemann-Cartan geometry. The world-sheet equations and boundary conditions are obtained in a manifestly covariant form. In the particle case, the resultant world-line equations turn out to exhibit a novel spin-curvature coupling. In particular, the spin of a zero-size particle does not couple to the background curvature. In the string case, the world-sheet dynamics is studied for some special choices of spin and torsion. As a result, the known coupling to the Kalb-Ramond antisymmetric external field is obtained. Geometrically, the Kalb-Ramond field has been recognized as a part of the torsion itself, rather than the torsion potential