Ethyl 2-{3-[(6-chloro­pyridin-3-yl)meth­yl]-2-(nitro­imino)­imidazolidin-1-yl}acetate

In the title compound, C13H16ClN5O4, the imidazole ring is in a slight envelope conformation. The dihedral angle between the pyridine ring and the four essentially planar atoms [maximum deviation 0.015 (2) Å] of the imidazole ring is 80.8 (1)°. In, the crystal, weak C—H⋯O and C—H⋯N hydrogen bonds are present. In addition, there are weak π–π stacking inter­actions between symmetry-related pyridine rings with a centroid–centroid distance of 3.807 (1) Å

Ethyl 3-[(6-chloro­pyridin-3-yl)meth­yl]-2-oxoimidazolidine-1-carboxyl­ate

In the title compound, C12H14ClN3O3, the imidazole ring adopts a half-chair conformation. The dihedral angle between the pyridine and imidazole rings is 70.0 (1)°. In the crystal, the molecules are linked by C—H⋯O inter­actions, forming chains parallel to the c axis

1-[(6-Chloro­pyridin-3-yl)meth­yl]imidazolidin-2-iminium chloride

The title compound, C9H12ClN4 +·Cl−, is a natural metabolic product of imidacloprid [systematic name: (E)-1-(6-chloro-3-pyridyl­meth­yl)-N-nitro­imidazolidin-2-yl­idene­amine] and was obtained by the reduction of the latter using Fe in HCl. The dihedral angle between the pyridine and imidazole rings is 62.09 (12)°. The crystal structure is stabilized by N—H⋯Cl and C—H⋯Cl inter­actions involving the chloride anion. The pyridine N and the chloride atoms are not involved in inter­molecular inter­actions

Copper-catalyzed substitution reactions of acylal with organomanganese reagents

989-994A mild method for the copper-catalyzed substitution of aldehyde acylals with organomanganese reagents is reported. This operationally simple C-C bond-forming protocol uses different Cu(I) catalysts. Acylal from trans-cinnamaldehyde furnishes conjugated addition product when reacted with alkyl and aryl organomanganese reagents in presence of 10 mol % of Cu(NCMe)₂(PPh₃)₂[BF₄] and 2 equivalent of Me₃Si-Cl as an accelerator. This reagent can be efficiently used in the substitution of one acetate group of aromatic acylal to form esters in high yield

5-Benzoyl-4-(4-fluorophenyl)-3,4-dihydropyrimidin-2(1H)-one

In the title molecule, C17H13FN2O2, the 3,4-dihydropyrimidine ring adopts a flattened sofa conformation with the flap atom (which bears the fluorophenyl substituent) deviating from the plane defined by the remaining five ring atoms by 0.281 (2) Å. This plane forms dihedral angles of 85.98 (6) and 60.63 (6)° with the 4-fluorophenyl and benzoyl-phenyl rings, respectively. The dihedral angle between the 4-fluorophenyl group and the benzene ring is 71.78 (6)°. In the crystal, N—H...O hydrogen bonds link molecules into inversion dimers that are further connected by another N—H...O interaction into a two-dimensional supramolecular structure parallel to (101)

2-[(Dimethylamino)methylidene]propanedinitrile

In the title moleclue, C6H7N3, the mean plane of the dimethylamino group [maximum deviation = 0.006 (2) Å] forms a dihedral angle of 7.95 (18)° with the mean plane of the propanedinitrile fragment [maximum deviation = 0.008 (2) Å]. In the crystal, weak C—H...N hydrogen bonds link the molecules into a three-dimensional network

An Efficient and Modified Biginelli-Type Synthesis of 3,4-Dihydro-1H-indeno[1,2-d]pyrimidine-2,5-dione Using Phosphorous Pentoxide

<div><p></p><p>A simple, clean and convenient one-pot method has been developed for the synthesis of 4-phenyl-3,4-dihydro-1H-indeno[1,2-d]pyrimidine-2,5-dione and 4-phenyl-2-thioxo-1,2,3,4-tetrahydro-5H-indeno[1,2-d]pyrimidine-5-one by multicomponent condensation of 1,3-indanedione, aromatic aldehydes and urea/thiourea using phosphorus pentoxide in ethanol under reflux conditions. The simple workup procedure and moderate to good yields within short time are some important features of this protocol. The synthesized compounds have been interpreted on the basis of their spectroscopic data.</p> </div