Reliable file transfer across a 10 megabit ethernet

The Ethernet communications network is a broadcast, multi-access system for local computing networks. Such a network was used to connect six 68000 based Charles River Data Systems for the purpose of file transfer. Each system required hardware installation and connection to the Ethernet cable. The software is an implementation which conforms to Xerox PUP File Transfer Protocol Specifications . This required the writing of two programs, the FTP user and the FTP server. Each program was built upon common communication packages which also had to be written. These communication routines transferred data over the Ethernet using the PARC Universal Packets (PUP) format

GPSS Compiler/Simulator

As with any large software project, the first priority of this thesis is program correctness in the GPSS compiler and correct simulation statistics. Several distinct processes are gone through in the construction of any compiler/simulator: development of specifications, indication of the goals, design, implementation, evaluation, and maintenance. The specifications of the GPSS compiler/simulator were introduced in the thesis proposal. The VAX/VMS 11/750 will be the machine which this GPSS compiler/simulator uses because of the supported \u27C language, a Command Language Definition Utility, and accessibility by this author. The implementation language, \u27C, was chosen based on ease of readability, ease of understanding, the simple but powerful data structures in the language, and the language\u27s support of modularization. Three milestones were identified for this thesis project: the parser, the pseudo code generator, and the simulator. Many projects are started with only the end product in mind, but the goals which were identified constitute essential checkpoints to validate the integrity of the compiler/simulator. There were three distinct design phases due to the milestone identification. The parser design encompassed the initial modular design layout of the source code for the entire compiler, and the design of the symbol table. Design of the pseudo code language had two constraints imposed: the ease of representation of the GPSS language in twoaddress code and the ease of integration of the pseudo language into the parser. Last but by no means unimportant was the design of the simulator, which controls the order of events within a model. After each design phase described above was completed, the implementation or writing of the source code was accomplished. The parser, the pseudo code generator, and the simulator carried through the \u27C capabilities of modularization and readability. Evaluation of the compiler was accomplished at three points: after the implementation of the parser, after the implementation of the pseudo code generator, and after the implementation of the simulator. The milestones or checkpoints specified in the identification of goals were essential in verifying the integrity of the system. Although maintenance is not a part of this thesis, the design phase took into consideration the ease of adding functionality to the implemented subset of GPSS. This compiler/simulator could be used as a base from which a more sophisticated and current version of the GPSS language would immerge

Optimization of Feeder Bus Routes for Electric Train Service using Ant Colony Algorithm

Nowadays, it has become more and more convenient for the citizens of Malaysia to move around the different states within the country as public transportation such as buses and trains offer affordable rates for their services. One of the most effective and efficient mode of transportation in Malaysia would be the Electric Train Service (ETS). It is a service that allows one to travel by train between cities of Ipoh and Kuala Lumpur inexpensively in a timely fashion. The ETS services may be excellent but the public transportation such as taxis and buses taking us to the station to board the trains may be inefficient and unreliable. In order to address this issue, an optimised feeder bus system is proposed. Hence, to achieve this, various optimisation algorithm needs to be studied and researched. The techniques that would need to have the capability to do route planning or selection while considering other criteria like time, cost and efficiency in addition of the displacement travelled. A model would then be developed using a tool such as Matlab with inputs of maps from Google Maps. This will consequently enable the feeder bus system to the ETS station in Ipoh to be optimised

Restoration of Penile Sensation after Dorsal Nerve Trauma in Cismen

Purpose: Loss of penis sensation or development of a painful penis can occur after injury to the dorsal branch of the pudendal nerve. Attempted relief of this problem through neurolysis of the dorsal nerve in the inferior pubic ramus canal has been reported rarely. While recovery of genital sensibility has been discussed frequently in transmen, this subject has been reported rarely in cismen. The purpose of this report is to review our experience with recovery of sensation after decompression of the dorsal branch of the pudendal nerve. Methods: A retrospective chart review was carried out from 2014 to 2018, of cismen who have had decompression of the dorsal branch of the pudendal nerve bilaterally. Patients were included if there was a thorough Urologic evaluation for sources of penile pain other than pudendal nerve injury, trial of antibiotics if prostatitis was suspected, normal magnetic resonance imaging (MRI) of the pelvis, and underwent a successful pudendal nerve block if pain was part of the symptomatology. Patients were excluded if they had previous genital surgery. The changes in penile symptoms (erection, ejaculation, ejaculatory pain, erogenous sensation, numbness, pain) were evaluated post-operatively. Secondary measures included the mechanism of injury, mean length of penile symptoms, mean time to improvement of first symptom, symptom recurrence, post-operative complications, and mean follow-up time. Results: Mechanisms of injury in this cohort of 8 men were 3 cycling (38%), 3 falls (38%) and 2 prostatectomy (28%). The mean length of penile symptoms prior to surgery was 254 weeks. Mean follow-up time was 9 weeks. Mean time to improvement in first symptom was 8 weeks. Of the 8 men included in this study, 6 (75%) had surgery bilaterally. Of the 3 men who had erectile dysfunction, normal erections were restored in 2 (67%) patients. Of the 2 patients unable to ejaculate, 1 (50%) patient regained ejaculatory function. Of the 5 patients with ejaculatory pain, complete relief of pain occurred in 3 (60%) patients, with partial relief in 2 (40%) patients. Of the 7 patients with loss of penile sensation, complete recovery of erogenous sensibility occurred in 6 (86%) patients, with partial relief in 1 (14%) patient. Of the 6 patients with penile pain, complete relief of pain occurred in 3 (50%) patients, with partial relief in 3 (50%) patients. Of the 4 patients with numbness, 1 (25%) patient had a complete return of feeling, with partial return in 3 (75%) patients. Complications: one patient had relief of pain but some residual penile numbness. Conclusions: Neurolysis of the dorsal nerve to the penis can be successful in relieving pain, restoring sensation and erectile function in cismen who sustained an injury along the inferior pubic ramus. This approach may prove useful to transmen who have scarring about the dorsal nerve after transgender surgery

Persistent Genital Arousal Disorder (PGAD): Treatment by Neurolysis of Dorsal Branch of Pudendal Nerve

Introduction: Persistent genital arousal disorder (PGAD) is the female perception that they are in a state of sexual arousal, without the ability of the arousal to be satisfied by orgasm. Aims: It is the hypothesis of this study that PGAD results from a minimal degree of nerve compression of the dorsal branch of the pudendal nerve. If this hypothesis were true, then PGAD could be treated by neurolysis of the dorsal branch of the pudendal nerve. Methods: A retrospective chart review was carried out from 2010 through 2018, of those women having neurolysis of the dorsal branch of the pudendal nerve. Patients were included in the cohort if they had a diagnosis of PGAD. All patients were assessed for demographic and clinical differences. Comparison between the pre-operative and postoperative groups was performed with descriptive statistics. Main Outcome Measures: The changes in clitoral symptoms (arousal, numbness, pain) evaluated post-operatively. Results: Of the 8 women included in this study, 7 were followed more than 24 weeks since surgery. Six of these women had the surgery bilaterally, and each of these had an excellent result (100%), meaning elimination of the arousal symptoms, pain, and the ability to resume normal sexual intercourse. The patient with unilateral decompression of the dorsal branch of the pudendal nerve had some improvement in arousal symptoms. This patient was the only reported case of symptom persistence. Clinical Implications: Provides a new treatment approach for patients with PGAD. Strength & Limitations: The main strength of the study is that this is the first article to report treatment of PGAD with neurolysis of the dorsal branch of the pudendal nerve. The main limitations of the study are the sample size and analysis of retrospectively collected data. Conclusion: The relief of arousal symptoms supports the hypothesis that PGAD is due to a minimal degree of compression of the dorsal branch of the pudendal nerve

Somebody : Song One-Step

https://digitalcommons.library.umaine.edu/mmb-vp/2479/thumbnail.jp

CRPS of the upper or lower extremity: surgical treatment outcomes

The hypothesis is explored that CRPS I (the "new" RSD) persists due to undiagnosed injured joint afferents, and/or cutaneous neuromas, and/or nerve compressions, and is, therefore, a misdiagnosed form of CRPS II (the "new" causalgia). An IRB-approved, retrospective chart review on a series of 100 consecutive patients with "RSD" identified 40 upper and 30 lower extremity patients for surgery based upon their history, physical examination, neurosensory testing, and nerve blocks. Based upon decreased pain medication usage and recovery of function, outcome in the upper extremity, at a mean of 27.9 months follow-up (range of 9 to 81 months), gave results that were excellent in 40% (16 of 40 patients), good in 40% (16 of 40 patients) and failure 20% (8 of 40 patients). In the lower extremity, at a mean of 23.0 months follow-up (range of 9 to 69 months) the results were excellent in 47% (14 of 30 patients), good in 33% (10 of 30 patients) and failure 20% (6 of 30 patients). It is concluded that most patients referred with a diagnosis of CRPS I have continuing pain input from injured joint or cutaneous afferents, and/or nerve compressions, and, therefore, similar to a patient with CRPS II, they can be treated successfully with an appropriate peripheral nerve surgical strategy

PENYESUAIAN STATUS HUKUM YAYASAN DAN PELAKSANAANNYA PADA YAYASAN PENDIDIKAN DAN DAKWAH ISLAM WIHDATUL UMMAH DI KABUPATEN TANAH DATAR

ABSTRACT The existence of foundation before our country have law were not set out clearly because there is no written rule that stated about foundation. Foundation which was established at that time just used common law in practice. Similarly, in carrying out the activities only based on customary law. The birth of Act No. 16 year 2001 as changed with Act No. 28 year 2004 about foundation are intended to provide correct understanding for society, ensure the certainty of law and restore the function as institution. Adjustment for foundation has already existed before the birth of foundation Act that is an obligation for getting law status and if the time limit has not specified, for the foundation that has not adjusted can not used the word "foundation" in front of its name. Since the adjustment for foundation that has existed before the birth of foundation law is an obligation, then the problem will be investigated is how the adjustment process for law institution and the impact that occurred for unadvised foundation. If claims relating to foundation operational incurred, the constraints that is faced by unadjusted foundation by Act no 16 of 2001 as changed by Act No. 28 year 2004 about foundation. This research use method of yuridis empiris approach which is research by looking at positive law aspect and its implementation or its practices in fact. Based on the result of research, on the basis of foundation budget adjustments still have some problems where the emptiness of builder and ignorance of the foundation about the importance of foundation adjustment for existing foundation before the birth of foundation Act. To extend the time limit for adjustment of the foundation which has been accompanied by adequate socialization and tougher sanction from the government, it will make the existing foundation to give support strongly for foundation that has established before the birth of foundation Act to adjust law status

White Paper AGA: Drug Development for Eosinophilic Esophagitis

Since first characterized in 2 small case series in the early 1990s, eosinophilic esophagitis (EoE) has emerged as a commonly identified cause of esophageal symptoms in children and adults. Although several highly effectively dietary, pharmacologic, and endoscopic therapies have been reported, none is currently approved by either the US Food and Drug Administration (FDA) or European regulatory authorities. Evolving diagnostic criteria have challenged drug development, in particular the recognition of complex interactions with the most prevalent esophageal disorder, gastroesophageal reflux disease (GERD). Heterogeneity in the clinical presentations of affected children and adults has created difficulties with uniform inclusion criteria and the development of disease-specific, patient-reported outcome (PRO) instruments. Furthermore, controversies regarding the appropriate therapeutic endpoints of EoE have impeded the design of clinical trials. Despite these obstacles, collaborative efforts by investigators, industry, the FDA, and patient advocacy groups have resulted in substantial progress in drug development in EoE over the past 2 decades. The purpose of this article is to summarize discussions on EoE based on the 2016 Drug Development Conference sponsored by the Center for Diagnostics and Therapeutics of the American Gastroenterological Association

Gene expression-phenotype associations in adults with eosinophilic esophagitis

Background: Gene expression patterns have not been extensively examined in the context of clinical features of eosinophilic esophagitis (EoE). Aims: To assess whether gene expression is associated with clinically defined phenotypes in adults with EoE. Methods: This was an analysis of prospectively collected esophageal biopsies in newly diagnosed EoE patients. We determined differential gene expression with a 94 gene panel in relation to clinical features and phenotypes. These included: endoscopic findings of esophageal rings, stricture, narrowing, linear furrows, exudates, edema, and dilation; an allergic phenotype; an inflammatory phenotype, and a fibrostenotic phenotype. Results: In 89 EoE cases analyzed, patients with exudates on endoscopy had multiple differences in gene expression compared to patients without exudates, though patients with exudates also had higher eosinophil counts (172 vs 106 eos/hpf; p =.01). Genes associated with esophageal narrowing included CCL26 (q-value = 0.028), ALOX15 (q = 0.011), GRK5 (q = 0.029), CPA3 (q = 0.012), and TRIM2 (q = 0.0027). TRIM2 was also associated with the fibrostenotic phenotype (q = 0.0051). No genes were associated with the inflammatory or atopic phenotypes, or with dilation. Conclusions: Multiple genes are associated with exudates, possibly related to higher eosinophil counts. However, a number of genes, including those related to both inflammation and remodelling, are associated with esophageal narrowing. In particular, TRIM2 is associated with clinical fibrotic phenotypes