On the Measurement of Roller Skew of Tapered Roller Bearings

Roller skew in roller bearings can cause heat generation and reduce bearing life. Therefore, design to minimise its occurrence is essential in bearing development. This study investigated the roller skew of a double row tapered roller bearing under various running conditions. A new system of measurement using two differential variable reluctance transducers (DVRT) was developed. It is evident that the roller skew of the double row tapered roller bearing can be measured. The shaft rotational speed has a significant effect on roller skew but the radial load has little effect.Peer reviewedFinal Accepted Versio

A survey of University of Richmond Evening School students : their motives, progress after study and the extent of assistance by employers in educational programs

The aim of this thesis is to suvey a representative group of Evening School students and business firms to gather qualitative data concerning the Evening School and present these data in a quantitative manner. Research was conducted by questionnaire in order to collect original source data. Replies to questionnaires have been analyzed. Tabulations of data are included throughout the text. A summary follows analyses of replies

Risk management in solitary agricultural work: new technologies for handling emergency and falls from great heights (SHADE)

Solitary work and agricultural activities are the scenarios of a large number of severe injuries and deaths, also because first aid may be difficult to achieve in isolated locations. This work proposes a technology available on smartphones that allows triggering an emergency call when a fall from height or an unconsciousness state is detected. The results of several tests, which include different detection algorithms and scenarios, are reported in this work. Tests performed with the aid of a dummy have allowed developing a reliable algorithm for the detection of dangerous situations. This system is available as an Android application

Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans

With the problem of parasitic nematode drug resistance increasing, vaccine development offers an alternative sustainable control approach. For some parasitic nematodes, native extracts enriched for specific proteins are highly protective. However, recombinant forms of these proteins have failed to replicate this protection. This is thought to be due to differences in glycosylation and/or conformation between native and recombinant proteins. We have exploited the free-living nematode Caenorhabditis elegans to examine its suitability as an alternative system for recombinant expression of parasitic nematode vaccine candidates. We focussed on Haemonchus contortus aminopeptidase H11 glycoprotein, which is enriched in a gut membrane fraction capable of inducing significant protection against this important ovine gastrointestinal nematode. We show that H. contortus H11 expressed in C. elegans is enzymatically active and MALDI mass spectrometry identifies similar di- and tri-fucosylated structures to those on native H11, with fucose at the 3- and/or 6-positions of the proximal GlcNAc. Some glycan structural differences were observed, such as lack of LDNF. Serum antibody to native H11 binds to C. elegans recombinant H11 and most of the antibody to rH11 or native H11 is directed to glycan moieties. Despite these similarities, no reduction in worm burden or faecal egg count was observed following immunisation of sheep with C. elegans-expressed recombinant H11 protein. The findings suggest that the di- and tri-fucosylated N-glycans expressed on rH11 do not contribute to the protective effect of H11 and that additional components present in native H11-enriched extract are likely required for enhancing the antibody response necessary for protection