Gartcosh Steel Mill regeneration project

New hi-tech, innovative businesses are springing up where Scotland's heavy industries once reigned supreme. Redevelopment of the former Ravenscraig steel works in Lanarkshire is continuing apace with a new town centre, complete with commercial facilities, soon to be constructed. The site of the former Gartcosh Steel Mill, also in Lanarkshire, is also being transformed, and architects and engineers from the University of Strathclyde are driving forward the plans. Gartcosh Business Interchange is set to become a new 50-hectare business location which has already been selected as the location for the major new office campus for Scotland's new FBI-style crime unit.It is anticipated that Gartcosh will create up to 170,000 sq ft of business space which could support up to 4000 jobs

Towards task-based personal information management evaluations

Personal Information Management (PIM) is a rapidly growing area of research concerned with how people store, manage and re-find information. A feature of PIM research is that many systems have been designed to assist users manage and re-find information, but very few have been evaluated.This has been noted by several scholars and explained by the difficulties involved in performing PIM evaluations.The difficulties include that people re-find information from within unique personal collections; researchers know little about the tasks that cause people to re-find information; and numerous privacy issues concerning personal information. In this paper we aim to facilitate PIM evaluations by addressing each of these difficulties. In the first part, we present a diary study of information re-finding tasks. The study examines the kind of tasks that require users to re-find information and produces a taxonomy of re-finding tasks for email messages and web pages. In the second part, we propose a task-based evaluation methodology based on our findings and examine the feasibility of the approach using two different methods of task creation

An improved optimistic three-stage model for the spread of HIV amongst injecting intravenous drug users

We start off this paper with a brief introduction to modeling Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) amongst sharing, injecting drug users (IDUs). Then we describe the mathematical model which we shall use which extends an existing model of the spread of HIV and AIDS amongst IDUs by incorporating loss of HIV infectivity over time. This is followed by the derivation of a key epidemiological parameter, the basic reproduction number R0. Next we give some analytical equilibrium, local and global stability results. We show that if R0 &gte 1 then the disease will always die out. For R0 > 1 there is the disease-free equilibrium (DFE) and a unique endemic equilibrium. The DFE is unstable. An approximation argument shows that we expect the endemic equilibrium to be locally stable. We next discuss a more realistic version of the model, relaxing the assumption that the number of addicts remains constant and obtain some results for this model. The subsequent section gives simulations for both models confirming that if R0 &gte 1 then the disease will die out and if R0 > 1 then if it is initially present the disease will tend to the unique endemic equilibrium. The simulation results are compared with the original model with no loss of HIV infectivity. Next the implications of these results for control strategies are considered. A brief summary concludes the paper

Mathematical modelling of internal HIV dynamics

We study a mathematical model for the viral dynamics of HIV in an infected individual in the presence of HAART. The paper starts with a literature review and then formulates the basic mathematical model. An expression for R0, the basic reproduction number of the virus under steady state application of HAART, is derived followed by an equilibrium and stability analysis. There is always a disease-free equilibrium (DFE) which is globally asymptotically stable for R0 1 then some simulations will die out whereas others will not. Stochastic simulations suggest that if R0 > 1 those which do not die out approach a stochastic quasi-equilibrium consisting of random uctuations about the non-trivial deterministic equilibrium levels, but the amplitude of these uctuations is so small that practically the system is at the non-trivial equilibrium. A brief discussion concludes the paper

Improving the dependability of research in personality and social psychology: recommendations for research and educational practice

pre-printThe Society for Personality and Social Psychology (SPSP) Presidential Task Force on Publication and Research Practices was appointed in response to concerns about the dependability and replicability of research findings in personality and social psychology, a problem that also plagues fields as diverse as physics, economics, biochemistry, medicine and cell biology. In this article the Task Force offers a brief statistical primer and recommendations for improving the dependability of scientific research. Recommendations for research practice include (1) describing and addressing the choice of N (sample size) and consequent issues of statistical power, (2) reporting effect sizes and 95% confidence intervals for findings, (3) avoiding "questionable research practices" that can undermine the assumptions underlying statistical procedures and inflate the probability of Type I error, (4) making available research materials necessary to replicate reported results, (5) adhering to SPSP's data sharing policy, (6) encouraging publication of high quality replication studies, and (7), maintaining flexibility and openness to alternative standards and methods when evaluating research. Recommendations for educational practice include (1) encouraging a culture of "getting it right" rather than "finding significant results," (2) teaching and encouraging transparency of data reporting, (3) improving methodological instruction on topics such as effect size, confidence intervals, statistical power, replication, and the effects of questionable research practices, and (4) modeling sound science and supporting junior researchers who seek to "get it right." The hope is that these recommendations can help lead the way to improved research practices and a more transparent research culture, throughout all of science

Design synthesis and shape generation

If we are to capitalise on the potential that a design approach might bring to innovation in business and society, we need to build a better understanding of the evolving skill-sets that designers will need and the contexts within which design might operate. This demands more discourse between those involved in cutting edge practice, the researchers who help to uncover principles, codify knowledge and create theories and the educators who are nurturing future design talent. This book promotes such a discourse by reporting on the work of twenty research teams who explored different facets of future design activity as part of Phase 2 of the UK's research council supported Designing for the 21st Century Research Initiative. Each of these contributions describes the origins of the project, the research team and their project aims, the research methods used and the new knowledge and understanding generated. Editor and Initiative Director, Professor Tom Inns, provides an introductory chapter that suggests ways the reader might navigate these viewpoints. This chapter concludes with an overview of the key lessons that might be learnt from this collection of design research activity

Persons, behaviors and situations: An agenda for personality psychology in the postwar era

a b s t r a c t The internecine war over the relative importance of persons and situations, triggered 40 years ago by Walter Mischel's Personality and Assessment, is largely over, so it is time for researchers to develop an agenda for personality psychology in the postwar era. The possibilities include a return to the status quo ante characterized by questionnaire-based research, focusing on narrower trait constructs than the ''global" traits that have undergone so much criticism, and concentrating upon within-person variance (as well as or even instead of between person variance) in behavior. Each of these possibilities offers some promise but also hazards that may be under-appreciated. The present article suggests that personality theory and research be re-organized in terms of the personality triad of persons, behaviors, and situations. A precondition for understanding the elements of this triad is better conceptualization and measurement of behavior and, especially, situations. While the interactions among these elements may turn out to be important, a first order of business is to understand the main effects of each element, a formidable but exciting research agenda that will entail a turn to broadly descriptive research rather than the testing of narrow, isolated hypotheses. Looking further ahead, a post-interactionist personality psychology may someday recognize that personality is a latent construct only indirectly indicated through behavior, and the ultimate understanding of that construct will be empirically tested by the ability to predict behavior in new and unique situations

Kuk i tidsplanen - Kvartær og Tertiær under opløsning

I sidste nummer af GeologiskNyt blev striden om Kvartærtiden omtalt: hvilke navne må vi bruge, og hvilke er forbudte? I denne artikel kommer vi nærmere ind på baggrunden for striden, men lad os allerede her fastslå, at ikke alene Kvartær, men også Tertiær stadig er tilladt

Regionally acquired intestinal failure data suggest an underestimate in national service requirements

Objectives, setting and patients: With complete case referral for prolonged parenteral nutrition (PN) beyond term equivalent, serving a stable population of 1.25 million people, we describe the long-term outcome and survival of patients referred to an intestinal failure (IF) nutrition support team over the first 8 years of existence at a regional paediatric centre, and extrapolate to potential numbers of national home parenteral nutrition (HPN) cases and intestinal transplantation data. Design and outcome measures: Retrospective analysis detailing patient demographics, interventions, use of HPN, occurrence of intestinal failure-associated liver disease (IFALD), and outcomes of enteral adaptation, survival, and referral for and receipt of organ transplantation. Results: 23 patients were referred over 8 years, 20 being PN dependent within the neonatal period. Diagnoses included short bowel syndrome (SBS) (18), neuromuscular abnormalities (4) and congenital enterocyte disorder (1). 12 696 days of PN were delivered with 314 confirmed episodes of sepsis at a median of 12 episodes per patient. 144 central venous catheters (CVCs) were required at a median of four per patient. IFALD occurred in 17 (73%) patients, with 10 (44%) referred for transplant assessment. Thirteen (56%) children received HPN. Overall mortality was 44%. A significant predictor for survival in the SBS group was residual bowel >40 cm (82% vs 28%, p = 0.049). Conclusions: Survival for IF at 56% was lower than reported from non-UK supra-regional centres, and nationally collected data, possibly reflecting pre-selected referral populations. Data from regional centres with complete ascertainment may be important both when counselling parents and when planning regional and national HPN and IF specialist services

Tissue Doppler imaging following paediatric cardiac surgery : early patterns of change and relationship to outcome

In this study, tissue Doppler imaging (TDI) was used to assess changes in ventricular function following repair of congenital heart defects. The relationship between TDI indices, myocardial injury and clinical outcome was explored. Forty-five children were studied; 35 withcardiac lesions and 10 controls. TDI was performed preoperatively, on admission to paediatric intensive care unit (PICU) and day 1. Regional myocardial Doppler signals were acquired from the right ventricle (RV), left ventricle (LV) and septum. TDI indices included: peak systolicvelocities, isovolumetric velocities (IVV) and isovolumetric acceleration (IVA). Preoperatively, bi-ventricular TDI velocities in the study groupwere reduced compared with normal controls. Postoperatively, RV velocities were significantly reduced and this persisted to day-1 (PreOp vs. PICU and day-1: 7.7+2.2 vs. 3.4+1.0, P < 0.0001 and 3.55+1.29, P < 0.0001). LV velocities initially declined but recovered towards baseline by day-1 (PreOp vs. PICU: 5.31+1.50 vs. 3.51+1.23, P < 0.0001). Isovolumetric parameters in all regions were reduced throughout the postoperative period. Troponin-I release correlated with longer X-clamp times (r=0.82, P < 0.0001) and reduced RV velocities (r=0.42, P=0.028). Reduced pre- and postoperative LV velocities correlated with longer ventilation (PreOp: r=0.54, P=0.002; PostOp: r=0.42, P=0.026). This study identified reduced postoperative RV velocities correlated with myocardial injury while reduced LV TDI correlated with longer postoperative ventilation