Exploring impacts of project leaders’ written expressions in virtual and fluid projects: The role of personality and emotion

This paper aims to tackle challenges of managing projects in highly virtual and fluid contexts, characterized by diversity, dispersion, digital dependence, unstable membership, and dynamic coordination and configuration. We investigate project leaders’ personality and emotion expressed in written expression and examine their impacts on collaboration outcomes. IBM Watson Personality Insights and Tone Analyzer were adopted to assess the leader’s personality and emotion. A computation model to classify collaboration patterns into taskwork-related and teamwork-related communication is under development. We report preliminary findings based on 417 weekly meetings between October 2018 and February 2020 in 8 open-source software teams around WordPress. The research results have the potential to inform researchers and practitioners about what personality profiles and emotions should be considered to foster collaboration in virtual and fluid projects. It is possible to extend the boundary condition of the traits school of leadership for project management in the new context

Applicability of perturbative QCD to Λb→Λc\Lambda_b \to \Lambda_c decays

We develop perturbative QCD factorization theorem for the semileptonic heavy baryon decay $\Lambda_b \to \Lambda_c l\bar{\nu}$, whose form factors are expressed as the convolutions of hard $b$ quark decay amplitudes with universal $\Lambda_b$ and $\Lambda_c$ baryon wave functions. Large logarithmic corrections are organized to all orders by the Sudakov resummation, which renders perturbative expansions more reliable. It is observed that perturbative QCD is applicable to $\Lambda_b \to \Lambda_c$ decays for velocity transfer greater than 1.2. Under requirement of heavy quark symmetry, we predict the branching ratio $B(\Lambda_b \to \Lambda_c l{\bar\nu})\sim 2$, and determine the $\Lambda_b$ and $\Lambda_c$ baryon wave functions.Comment: 12 pages in Latex file, 3 figures in postscript files, some results are changed, but the conclusion is the sam

Numerical investigation of aerodynamic droplet breakup in a high temperature gas environment

The Navier-Stokes equations, energy and vapor transport equations coupled with the VOF methodology and a vaporization rate model are numerically solved to predict aerodynamic droplet breakup in a high temperature gas environment. The numerical model accounts for variable properties and uses an adaptive local grid refinement technique on the gas-liquid interface to enhance the accuracy of the computations. The parameters examined include Weber (We) numbers in the range 15-90 and gas phase temperatures in the range 400-1000 K for a volatile n-heptane droplet. Initially isothermal flow conditions are examined in order to assess the effect of Weber (We) and Reynolds (Re) number. The latter was altered by varying the gas phase properties in the aforementioned temperature range. It is verified that the We number is the controlling parameter, while the Re number affects the droplet breakup at low We number conditions. The inclusion of droplet heating and evaporation mechanisms has revealed that heating effects have generally a small impact on the phenomenon due to its short duration except for low We number cases. Droplet deformation enhances heat transfer and droplet evaporation. An improved 0-D model is proposed, able to predict the droplet heating and vaporization of highly deformed droplets

Rheumatoid Arthritis Associated with Dry Eye Disease and Corneal Surface Damage: A Nationwide Matched Cohort Study

Rheumatoid arthritis is potentially connected to ocular disorders, such as corneal inflammation and lacrimal gland destruction. This study aimed to evaluate the risk of dry eye disease (DED) and corneal surface damage among patients with rheumatoid arthritis. In a nationwide cohort study, we utilized Taiwan’s National Health Insurance research database and conducted propensity score matching to compare the risks of DED and corneal surface damage between patients with and without rheumatoid arthritis. Proportional hazards regression analyses were used to calculate the adjusted hazard ratio (aHR) and 95% confidence interval (CI) for the outcomes of interest. The matching procedure generated 33,398 matched pairs with 501,377 person-years of follow-up for analyses. The incidence of DED was 23.14 and 10.25 per 1000 person-years in patients with and without rheumatoid arthritis, respectively. After adjusting for covariates, rheumatoid arthritis was significantly associated with DED (aHR: 2.03, 95% CI: 1.93–2.13, p p < 0.0001) compared to control subjects. Other independent factors for corneal surface damage were age and sleeping disorders. Rheumatoid arthritis was associated with an increased risk of DED and corneal surface damage. Ophthalmological surveillance is required to prevent vision-threatening complications in this susceptible population

Survival curves stratified by rs1625649 genotypes in patients with <i>MGMT</i> methylated GBM.

<p>(A) Progression-free survival and (B) overall survival of the study cohort. Patients with homozygous rs1625649 (AA genotype) had longer progression-free survival than those with heterozygous (CA genotype) or wild type (CC genotype) rs1625649. However, the difference in overall survival did not reach statistical significance.</p

The <i>MGMT</i> promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with <i>MGMT</i> methylated glioblastoma

<div><p>Promoter methylation is the most significant mechanism to regulate O⁶-methylguanine-DNA-methyltransferase (<i>MGMT</i>) expression. Single-nucleotide polymorphisms (SNPs) in the <i>MGMT</i> promoter region may also play a role. The aim of this study was to evaluate the clinical significance of SNPs in the <i>MGMT</i> promoter region of glioblastoma. Genomic DNAs from 118 glioblastomas were collected for polymerase chain reaction (PCR) amplification. Sanger sequencing was used to sequence the <i>MGMT</i> promoter region to detect SNPs. The results were correlated with <i>MGMT</i> status and patient survival. Rs1625649 was the only polymorphic SNP located at the <i>MGMT</i> promoter region in 37.5% of glioblastomas. Homozygous rs1625649 (AA genotype) was correlated with a higher <i>MGMT</i> methylation level and a lower protein expression, but the result was not statistically significant. In patients with <i>MGMT</i> methylated glioblastoma, cases with homozygous rs1625649 (AA genotype) were significantly associated with a lack of MGMT protein expression and a better progression-free survival (PFS) than the cases with wild type rs1625649 (CC genotype) or heterozygous rs1625649 (CA genotype). The survival impact was significant in multivariate analyses. In conclusion, the <i>MGMT</i> promoter homozygous rs1625649 (AA genotype) was found to correlate with a better PFS in patients with <i>MGMT</i> methylated glioblastoma.</p></div

Association between rs1625649 genotypes, <i>MGMT</i> status and clinical characteristics.

<p>Association between rs1625649 genotypes, <i>MGMT</i> status and clinical characteristics.</p

Association between rs1625649 genotypes and MGMT status subgrouped by promoter methylation (qMSP) and protein expression (IHC).

<p>Association between rs1625649 genotypes and MGMT status subgrouped by promoter methylation (qMSP) and protein expression (IHC).</p