69 research outputs found
Dissipation Instability in the Accretion Disk
The model of a geometrically thin gaseous disk in the external gravitational
potential is considered. The dinamics of small nonaxisymmetric perturbations in
the plane of the accretion disk with dissipative effects is investigated. It is
showed, that conditions of development and parameters of unstable oscillation
modes in the opticaly thick accretion disk are strongly depended on the models
of viscosity and opacity.Comment: Plain TeX, 6 pages, 2 figures (GIF), Submitted to Astron. Astrophys.
Transaction
New Analytical Formula for Supercritical Accretion Flows
We examine a new family of global analytic solutions for optically thick
accretion disks, which includes the supercritical accretion regime. We found
that the ratio of the advection cooling rate, , to the viscous
heating rate, , i.e., , can be
represented by an analytical form dependent on the radius and the mass
accretion rate. The new analytic solutions can be characterized by the
photon-trapping radius, \rtrap, inside which the accretion time is less than
the photon diffusion time in the vertical direction; the nature of the
solutions changes significantly as this radius is crossed. Inside the trapping
radius,
approaches , which corresponds to the advection-dominated
limit (), whereas outside the trapping radius, the radial dependence
of changes to , which corresponds to the
radiative-cooling-dominated limit. The analytical formula for derived here
smoothly connects these two regimes. The set of new analytic solutions
reproduces well the global disk structure obtained by numerical integration
over a wide range of mass accretion rates, including the supercritical
accretion regime. In particular, the effective temperature profiles for our new
solutions are in good agreement with those obtained from numerical solutions.
Therefore, the new solutions will provide a useful tool not only for evaluating
the observational properties of accretion flows, but also for investigating the
mass evolution of black holes in the presence of supercritical accretion flows.Comment: 14 pages, 7 figures, accepted for publication in the Astrophysical
Journa
A Search for Aperiodic Millisecond Variability in Cygnus X-1
We have conducted a search for aperiodic millisecond variability in the
integrated 1 to 25 keV X-ray region of Cyg X-1. We have examined HEAO A-1
archival data and Rossi X-ray Timing Explorer (RXTE) guest observer data for
evidence of excess power above the Poisson noise floor using the relative
integral power analysis and the Fourier transform method. Our results are in
disagreement with the results of Meekins et al. (1984). We attribute the
discrepancy to an instrumental effect for which Meekins et al.(1984) did not
apply a correction. With the correction we see no evidence for excess power
above 25 Hz in the HEAO A-1 data. Our analysis of RXTE data is in agreement
with previously published results of different data sets and shows no sign of
excess power above 30 Hz.Comment: 29 pages, 12 figures, to be submitted to Ap
The Ensemble Photometric Variability of ~25000 Quasars in the Sloan Digital Sky Survey
Using a sample of over 25000 spectroscopically confirmed quasars from the
Sloan Digital Sky Survey, we show how quasar variability in the rest frame
optical/UV regime depends upon rest frame time lag, luminosity, rest
wavelength, redshift, the presence of radio and X-ray emission, and the
presence of broad absorption line systems. The time dependence of variability
(the structure function) is well-fit by a single power law on timescales from
days to years. There is an anti-correlation of variability amplitude with rest
wavelength, and quasars are systematically bluer when brighter at all
redshifts. There is a strong anti-correlation of variability with quasar
luminosity. There is also a significant positive correlation of variability
amplitude with redshift, indicating evolution of the quasar population or the
variability mechanism. We parameterize all of these relationships. Quasars with
RASS X-ray detections are significantly more variable (at optical/UV
wavelengths) than those without, and radio loud quasars are marginally more
variable than their radio weak counterparts. We find no significant difference
in the variability of quasars with and without broad absorption line troughs.
Models involving multiple discrete events or gravitational microlensing are
unlikely by themselves to account for the data. So-called accretion disk
instability models are promising, but more quantitative predictions are needed.Comment: 41 pages, 21 figures, AASTeX, Accepted for publication in Ap
Lower respiratory tract infection and rapid expansion of an abdominal aortic aneurysm: a case report
<p>Abstract</p> <p>Introduction</p> <p>The rate of abdominal aortic aneurysm expansion is related to multiple factors. There is some evidence that inflammation can accelerate aneurysm expansion. However, the association between pulmonary sepsis and rapid abdominal aortic aneurysm expansion is rarely reported.</p> <p>Case presentation</p> <p>Here we present a case of a rapidly expanding abdominal aortic aneurysm in a 68-year-old Caucasian man with a concomitant lower respiratory tract infection and systemic sepsis requiring intensive monitoring and urgent endovascular intervention. Our patient had an uncomplicated post-operative recovery and a follow-up computed tomography scan at one month demonstrated no evidence of an endoleak.</p> <p>Conclusion</p> <p>This case highlights the potential association between pulmonary sepsis and rapid abdominal aortic aneurysm expansion. In such cases, a policy of frequent monitoring should be adopted to identify those patients requiring definitive management.</p
XPS characterization of (copper-based) coloured stains formed on limestone surfaces of outdoor Roman monuments
Limestone basements holding bronzes or other copper alloys artefacts such as sculptures, decorations and dedicatory inscriptions are frequently met both in modern and ancient monuments. In outdoor conditions, such a combination implies the corrosion products of the copper based alloy, directly exposed to rainwater, will be drained off and migrate through the porous surfaces, forming stains of different colours and intensities, finally causing the limestone structures to deteriorate
Pion production in the inner disk around Cygnus X-1
Neutron production via ^{4}He breakup and p(p, n{pi}^+)p is considered in the
innermost region of an accretion disk surrounding a Kerr Black Hole. These
reactions occur in a plasma in Wien equilibrium, where (radiatively produced)
pair production equals annihilation. Cooling of the disk is assumed to be due
to unsaturated inverse Comptonization of external soft photons and to the
energy needed to ignite both nuclear reactions. Assuming matter composition of
90% Hydrogen and 10% He, it is shown that, close to the border of this region,
neutron production is essentially from ^{4}He breakup. Close to the horizon,
the contribution from p(p, n{pi}^+)p to the neutron production is comparable to
that from the breakup. It is shown that the viscosity generated by the
collisions of the accreting matter with the neutrons may drive stationary
accretion, for accretion rates below a critical value. In this case, solution
to the disk equations is double-valued and for both solutions protons
overnumber the pairs. It is claimed that these solutions may mimic the states
of high and low luminosity observed in Cygnus X-1 and related sources. This
would be explained either by the coupling of thermal instability to the
peculiar behavior of the viscosity parameter alpha with the ion temperature
that may intermittently switch accretion off or by the impossibility of a
perfect tuning for both thermal and pair equilibrium in the disk, a fact that
forces the system to undergo a kind of limit cycle behavior around the upper
solution.Comment: 23 pages, 11 figure
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
Although genome-wide association studies have identified over 100 risk loci that explain ~33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of European and African American ancestries combined with cell-type-specific epigenetic data to build a genomic atlas of single-nucleotide polymorphism (SNP) heritability in PrCa. We find significant differences in heritability between variants in prostate-relevant epigenetic marks defined in normal versus tumour tissue as well as between tissue and cell lines. The majority of SNP heritability lies in regions marked by H3k27 acetylation in prostate adenoc7arcinoma cell line (LNCaP) or by DNaseI hypersensitive sites in cancer cell lines. We find a high degree of similarity between European and African American ancestries suggesting a similar genetic architecture from common variation underlying PrCa risk. Our findings showcase the power of integrating functional annotation with genetic data to understand the genetic basis of PrCa
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
Although genome-wide association studies have identified over 100 risk loci that explain similar to 33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of European and African American ancestries combined with cell-type-specific epigenetic data to build a genomic atlas of single-nucleotide polymorphism (SNP) heritability in PrCa. We find significant differences in heritability between variants in prostate-relevant epigenetic marks defined in normal versus tumour tissue as well as between tissue and cell lines. The majority of SNP heritability lies in regions marked by H3k27 acetylation in prostate adenoc7arcinoma cell line (LNCaP) or by DNaseI hypersensitive sites in cancer cell lines. We find a high degree of similarity between European and African American ancestries suggesting a similar genetic architecture from common variation underlying PrCa risk. Our findings showcase the power of integrating functional annotation with genetic data to understand the genetic basis of PrCa
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain âŒ38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
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