24,874 research outputs found

    A new algorithm for horizontal capture trajectories

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    An algorithm which transfers an aircraft from an initial position and heading to a final position and heading was developed for onboard synthesis of horizontal flight paths. The algorithm finds all solutions possible, and selects the one with minimum path length. Degenerate conditions in which one or more of the basic segments is missing are handled without difficulty. The solution to this problem is derived, and a FORTRAN listing of the algorithm is provided

    Fuel-conservative guidance system for powered-lift aircraft

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    A concept for automatic terminal area guidance, comprising two modes of operation, was developed and evaluated in flight tests. In the predictive mode, fuel efficient approach trajectories are synthesized in fast time. In the tracking mode, the synthesized trajectories are reconstructed and tracked automatically. An energy rate performance model derived from the lift, drag, and propulsion system characteristics of the aircraft is used in the synthesis algorithm. The method optimizes the trajectory for the initial aircraft position and wind and temperature profiles encountered during each landing approach. The design theory and the results of simulations and flight tests using the Augmentor Wing Jet STOL Research Aircraft are described

    The envirome and the connectome: exploring the structural noise in the human brain associated with socioeconomic deprivation

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    Complex cognitive functions are widely recognized to be the result of a number of brain regions working together as large-scale networks. Recently, complex network analysis has been used to characterize various structural properties of the large scale network organization of the brain. For example, the human brain has been found to have a modular architecture i.e. regions within the network form communities (modules) with more connections between regions within the community compared to regions outside it. The aim of this study was to examine the modular and overlapping modular architecture of the brain networks using complex network analysis. We also examined the association between neighborhood level deprivation and brain network structure – modularity and grey nodes. We compared network structure derived from anatomical MRI scans of 42 middle-aged neurologically healthy men from the least (LD) and the most deprived (MD) neighborhoods of Glasgow with their corresponding random networks. Cortical morphological covariance networks were constructed from the cortical thickness derived from the MRI scans of the brain. For a given modularity threshold, networks derived from the MD group showed similar number of modules compared to their corresponding random networks, while networks derived from the LD group had more modules compared to their corresponding random networks. The MD group also had fewer grey nodes – a measure of overlapping modular structure. These results suggest that apparent structural difference in brain networks may be driven by differences in cortical thicknesses between groups. This demonstrates a structural organization that is consistent with a system that is less robust and less efficient in information processing. These findings provide some evidence of the relationship between socioeconomic deprivation and brain network topology

    The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression

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    The I-R system of hybrid dysgenesis in Drosophila melanogaster is controlled by a long interspersed nuclear element-like retroposon, the I factor. Transposition of the I factor occurs at a high frequency only in the ovaries of females produced by crossing males of inducer strains that contain functional I factors with females of reactive strains that lack them. In this study, the 5' untranslated region of the I factor was joined to the chloramphenicol acetyltransferase gene, and activity was assayed in transfected D. melanogaster tissue culture cells and transformed flies. The results have identified a promoter that lies within the first 186 bp of the I factor. Deletion analysis shows that nucleotides + 1 to + 40 are sufficient for high promoter activity and accurate transcription initiation. This region contains sequences that are found in a class of RNA polymerase II promoters that lack both a TATA box and CpG-rich motifs. In transformed flies, high levels of expression from nucleotides + 1 to + 186 are confined to the ovaries of reactive females, suggesting that the promoter is involved in the tissue and cytotype specificity of transposition.</p

    Eight years of organic farming at Pwllpeiran – livestock production and the financial performance of organic upland

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    This report was presented at the UK Organic Research 2002 Conference. Established for 8 years, this project evaluates the practicalities of organic beef and sheep production on an upland farm in an ESA. Grassland productivity, stocking rates and animal performance are closely related to seasonal variations in the clover content of the small area of improved land. Improving sales have been offset by increasing input costs. Subsidy payments assist financial performance, but ESA prescriptions effectively prevent increased production

    The use of feed blocks as supplementation for the upland hill flock: (2) Cost effective lamb production

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    This report was presented at the UK Organic Research 2002 Conference of the Colloquium of Organic Researchers (COR).Under EU organic livestock regulations introduced in 2000, new restrictions were placed on the use of bought-in feedstuffs in hill systems. These reduced the non-organic annual percentage previously allowed in LFAs from 20% to 10% of annual dry matter intake. A further stepping down of these allowances may be introduced ahead of a complete ban in 2005. Bought-in feed supplements must therefore, be used strategically and offer “best value for money” in terms of ewe performance and lamb growth. The economic cost of supplementing the diet of twin-rearing ewes post lambing with either an approved non-organic feed block + half ration of commercial concentrate mix (B+CCM) or full ration commercial concentrate mix (CCM) was investigated. Lambs reared by ewes receiving the B+CCM diet had a greater liveweight gain than those reared by ewes receiving the CCM diet per kg of ewe supplementary feed. The costs in terms of kg lamb liveweight were lower for the B+CCM ewes than the CCM ewe

    The effect of electron beam pitch angle and density gradient on solar type III radio bursts

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    Copyright 2012 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Physics of Plasmas 19, 112903 (2012) and may be found at .supplemental material at http://astro.qmul.ac.uk/~tsiklauri/sp.htmlsupplemental material at http://astro.qmul.ac.uk/~tsiklauri/sp.htm

    Musculoskeletal adaptations to physical interventions in spinal cord injury

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    Wireworm Control using Fodder Rape and Mustard – evaluating the use of brassica green manures for the control of wireworm (Agriotes spp.) in organic crops

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    In a field experiment at ADAS Pwllpeiran in 2001, brassica green manures were grown for 6 weeks and dug in before planting King Edward potatoes, to see if they suppressed wireworm in the crop. There was a trend for potatoes grown after mustard to suffer less damage from both wireworms and slugs than potatoes grown after fodder rape or no green manure, but the differences were not significant. Further trials, with longer green manuring periods, are needed to establish if there is a benefit, and whether the breakdown products of brassica green manures are toxic to wireworms

    Evolutionary Divergence in Developmental Strategies and Neuromodulatory Control Systems of Two Amphibian Locomotor Networks

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    Attempts to understand the neural mechanisms which produce behaviour must consider both prevailing sensory cues and the central cellular and synaptic changes they direct. At each level, neuromodulation can additionally shape the final output. We have investigated neuromodulation in the developing spinal motor networks in hatchling tadpoles of two closely related amphibians, Xenopus laevis and Rana temporaria to examine the subtle differences in their behaviours that could be attributed to their evolutionary divergence. At the point of hatching, both species can swim in response to a mechanosensory stimulus, however Rana embryos often display a more forceful, non-locomotory coiling behaviour. Whilst the synaptic drive that underlies these behaviours appears similar, subtle inter-specific differences in neuronal properties shape motor outputs in different ways. For example, Rana neurons express N-methyl-D-aspartate (NMDA)/serotonin (5-HT)-dependent oscillations, not present in hatchling Xenopus and many also exhibit a prominent slow spike after-hyperpolarisation. Such properties may endow the spinal circuitry of Rana with the ability to produce a more flexible range of outputs. Finally, we compare the roles of the neuromodulators 5-HT, noradrenaline (NA) and nitric oxide (NO) in shaping motor outputs. 5-HT increases burst durations during swimming in both Xenopus and Rana, but 5-HT dramatically slows the cycle period in Rana with little effect in Xenopus. Three distinct, but presumably homologous NO-containing brainstem clusters of neurons have been described, yet the effects of NO differ between species. In Xenopus, NO slows and shortens swimming in a manner similar to NA, yet in Rana NO and NA elicit the non-rhythmic coiling pattern
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