60 research outputs found
Assessment of ocean prediction model for Naval Operations using acoustic preset
OCEANS2005, MTS/IEEE Conference Proceedings, DVD-ROMThe outcome of a battlefield engagement is
often determined by the advantages and disadvantages held
by each adversary. On the modern battlefield, the possessor
of the best technology often has the upper hand, but only if
that advanced technology is used properly and efficiently. In
order to exploit this advantage and optimize the effectiveness
of high technology sensor and weapon systems, it is essential
to understand the impact on them by the environment. In the
arena of Anti-Submarine Warfare (ASW), the ocean
environment determines the performance of the acoustic
sensors employed and the success of any associated weapon
systems. Since acoustic sensors detect underwater sound
waves, understanding how those waves propagate is crucial
to knowing how the sensors will perform and being able to
optimize their performance in a given situation. To gain this
understanding, an accurate depiction of the ocean
environment is necessary. How acoustic waves propagate
from one location to another under water is determined by
many factors, some of which are described by the sound
speed profile (SSP). If the environmental properties of
temperature and salinity are known over the entire depth
range, the SSP can be compiled by using them in an
empirical formula to calculate the expected sound speed in a
vertical column of water. One way to determine these
environmental properties is to measure them in situ, such as
by conductivity-temperature-depth or expendable
bathythermograph (XBT) casts. This method is not always
tactically feasible and only gives the vertical profile at one location producing a very limited picture of the regional
ocean structure. Another method is to estimate the ocean
conditions using numerical models. The valued-aided
ocean prediction models to ASW is assessed in this study.
Such quantitative analyses offer a means to optimize the
ASW requirements and technical capabilities of new weapon
systems. We use observed and modeled 3-D fields of
temperature, salinity, and sound speed. Compare model
profiles to observed profiles. Do ocean models predict the
vertical features of the observational data? Run
representative modeled and observed SSP profiles through
Navy’s acoustic models to see if there is an acoustic
difference in propagation and weapon preset
Methylene Blue Near-Infrared Fluorescence Imaging in Breast Cancer Sentinel Node Biopsy
Introduction: Fluorescence-based navigation for breast cancer sentinel node biopsy is a novel method that uses indocyanine green as a fluorophore. However, methylene blue (MB) also has some fluorescent properties. This study is the first in a clinical series presenting the possible use of MB as a fluorescent dye for the identification of sentinel nodes in breast sentinel node biopsy. Material and methods: Forty-nine patients with breast cancer who underwent sentinel node biopsy procedures were enrolled in the study. All patients underwent standard simultaneous injection of nanocolloid and MB. We visualized and assessed the sentinel nodes and the lymphatic channels transcutaneously, with and without fluorescence, and calculated the signal-to-background ratio (SBR). We also analyzed the corresponding fluorescence intensity of various dilutions of MB. Results: In twenty-three patients (46.9%), the location of the sentinel node, or the end of the lymphatic path, was visible transcutaneously. The median SBR for transcutaneous sentinel node location was 1.69 (range 1.66–4.35). Lymphatic channels were visible under fluorescence in 14 patients (28.6%) prior to visualization by the naked eye, with an average SBR of 2.01 (range 1.14–5.6). The sentinel node was visible under fluorescence in 25 patients (51%). The median SBR for sentinel node visualization with MB fluorescence was 2.54 (range 1.34–6.86). Sentinel nodes were visualized faster under fluorescence during sentinel node preparation. Factors associated with the rate of visualization included diabetes (p = 0.001), neoadjuvant chemotherapy (p = 0.003), and multifocality (p = 0.004). The best fluorescence was obtained using 40 µM (0.0128 mg/mL) MB, but we also observed a clinically relevant dilution range between 20 µM (0.0064 mg/mL) and 100 µM (0.032 mg/mL). Conclusions: For the first time, we propose the clinical usage of MB as a fluorophore for fluorescence-guided sentinel node biopsy in breast cancer patients. The quenching effect of the dye may be the reason for its poor detection rate. Our analysis of different concentrations of MB suggests a need for a detailed clinical analysis to highlight the practical usefulness of the dye
Satellite Data Assimilation for Naval Undersea Capability Improvement
OCEANS 2003, MTS/IEEE Conference Proceedings, DVD-RO
Impact of GFO satellite on naval antisubmarine warfare
NATO RTB-SPSM01 Specialists Meeting on "Emerging and Future Technologies for Space Based Operations Support to NATO Military Operations", DVD-ROMThe purpose of this study is to assess the benefit of assimilating satellite altimeter data especially the US
Navy’s GFO into the Modular Ocean Data Assimilation System (MODAS). To accomplish this, two different
MODAS fields are used by the Weapon Acoustic Preset Program (WAPP) to determine suggested presets for
a Mk 48 variant torpedo. The MODAS fields differ in that one uses altimeter data assimilated from three
satellites while the other uses no altimeter data. The metric used to compare the two sets of outputs is the
relative difference in acoustic coverage area generated by WAPP. Output presets are created for five
different scenarios, two Anti-Surface Warfare scenarios and three Anti-Submarine Warfare scenarios, in each
of three regions: the East China Sea, Sea of Japan, and an area south of Japan that includes the Kuroshio
current. Analysis of the output reveals that, in some situations, WAPP output is very sensitive to the inclusion
of the altimeter data because of the resulting differences in the subsurface predictions. The change in weapon
presets could be so much that the effectiveness of the weapon might be affected
Ocean nowcast/forecast systems for improvement of Naval undersea capabilities
Marine Technology Society Journal, 41 (2), Summer 2007The U.S. Navy is a major investor in ocean model development. The pay-off of such an
investment is the value-added ocean nowcast/forecast systems on naval operations and
warfare effectiveness. The purpose of this paper is to investigate the value added of the
Navy’s nowcast/forecast system to naval antisubmarine warfare (ASW) and anti-surface
warfare (ASUW). The nowcast/forecast versus observational fields were used by the Weapon
Acoustic Preset Program (WAPP) to determine the suggested presets for Mk 48 variant
torpedo. The metric used to compare the two sets of outputs is the relative difference in
acoustic coverage area generated by WAPP. Output presets are created for five different
scenarios, two ASUW scenarios and three ASW scenarios in the South China Sea. The same
metrics used in the nowcast/forecast case were used to generate and compare the acoustic
coverage. Analysis of the output reveals that the ocean forecast system outperformed the
nowcast system in most scenarios
Satellite data assimilation for improvement of Naval undersea capability
Marine Technology Society Journal, 38 (1), 11-23.Impact of satellite data assimilation on naval undersea capability is investigated
using ocean hydrographic products without and with satellite data assimilation. The
former is the Navy’s Global Digital Environmental Model (GDEM), providing a monthly
mean; the latter is the Modular Ocean Data Assimilation System (MODAS) providing
synoptic analyses based upon satellite data. The two environmental datasets are taken
as the input into the Weapon Acoustic Preset Program to determine the suggested
presets for an Mk 48 torpedo. The acoustic coverage area generated by the program
will be used as the metric to compare the two sets of outputs. The output presets
were created for two different scenarios, an anti-surface warfare (ASUW) and an
anti-submarine warfare (ASW); and three different depth bands, shallow, mid, and
deep. After analyzing the output, it became clear that there was a great difference in
the presets for the shallow depth band, and that as depth increased, the difference
between the presets decreased. Therefore, the MODAS product, and in turn the satellite
data assimilation, had greatest impact in the shallow depth band. The ASW
presets also seemed to be slightly less sensitive to differences than did presets in
the ASUW scenario
Sensitivity of satellite altimetry data assimilation on weapon acoustic preset using MODAS
IEEE Journal of Oceanic Engineering, Vol. 32, No. 2, 453-468.The article of record as published may be located at http://dx.doi.org/10.1109/JOE.2006.888869The purpose of this research is to assess the benefit
of assimilating satellite altimeter data for naval undersea warfare.
To accomplish this, sensitivity of the weapon acoustic preset
program (WAPP) for the Mk 48 variant torpedo to changes in the
sound-speed profile (SSP) is analyzed with SSP derived from the
modular ocean data assimilation system (MODAS). The MODAS
fields differ in that one uses altimeter data assimilated from three
satellites while the other uses no altimeter data. The metric used to
compare the two sets of outputs is the relative difference in acoustic
coverage area generated by WAPP. Output presets are created
for five different scenarios, two antisurface warfare (ASUW)
scenarios, and three antisubmarine warfare (ASW) scenarios, in
each of three regions: the East China Sea, Sea of Japan, and an
area south of Japan that includes the Kuroshio currents. Analysis
of the output reveals that, in some situations, WAPP output is
very sensitive to the inclusion of the altimeter data because of the
resulting differences in the subsurface predictions. The change in
weapon presets can be so large that the effectiveness of the weapon
may be affected
Shane_et_al_Blood_Meal_Induced_Promoters_from_Asaia
This data package includes the files needed to reproduce the quantitative analyses of the following paper:Shane, JL., Grogan, CL., Cwalina, C., and David J. Lampe: Blood meal-induced inhibition of vector-borne disease by transgenic microbiot
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