7 research outputs found

    ¿Qué modelos para las niñas? : una investigación sobre los libros ilustrados

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    La investigación ha sido realizada con la ayuda de la Comisión EuropeaEl proyecto 'Atención Album' investiga los álbumes ilustrados destinados a los niños de 0 a 9 años. Aquí se analiza la casi totalidad de los álbumes producidos durante 1994 en Francia, Italia y España. A través de una red de observaciones destinadas al análisis estadístico se aclara cuántos y de qué sexo son los personajes representados y en qué lugares se mueven, cuáles son sus funciones, acciones y relaciones con los otros personajes. La investigación ha confirmado que el mundo que muestran los álbumes es sexualmente discriminatorio y mayoritariamente masculino y sólo en raras ocasiones se dan situaciones en que los dos sexos cohabitan, comunican e intercambian. Los resultados de los tres países son convergentes.ParísBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5; 28014 Madrid; Tel. +34917748000; [email protected]

    New Strategies to Develop Novel Pain Therapies: Addressing Thermoreceptors from Different Points of View

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    Risk of COVID-19 after natural infection or vaccinationResearch in context

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    Summary: Background: While vaccines have established utility against COVID-19, phase 3 efficacy studies have generally not comprehensively evaluated protection provided by previous infection or hybrid immunity (previous infection plus vaccination). Individual patient data from US government-supported harmonized vaccine trials provide an unprecedented sample population to address this issue. We characterized the protective efficacy of previous SARS-CoV-2 infection and hybrid immunity against COVID-19 early in the pandemic over three-to six-month follow-up and compared with vaccine-associated protection. Methods: In this post-hoc cross-protocol analysis of the Moderna, AstraZeneca, Janssen, and Novavax COVID-19 vaccine clinical trials, we allocated participants into four groups based on previous-infection status at enrolment and treatment: no previous infection/placebo; previous infection/placebo; no previous infection/vaccine; and previous infection/vaccine. The main outcome was RT-PCR-confirmed COVID-19 >7–15 days (per original protocols) after final study injection. We calculated crude and adjusted efficacy measures. Findings: Previous infection/placebo participants had a 92% decreased risk of future COVID-19 compared to no previous infection/placebo participants (overall hazard ratio [HR] ratio: 0.08; 95% CI: 0.05–0.13). Among single-dose Janssen participants, hybrid immunity conferred greater protection than vaccine alone (HR: 0.03; 95% CI: 0.01–0.10). Too few infections were observed to draw statistical inferences comparing hybrid immunity to vaccine alone for other trials. Vaccination, previous infection, and hybrid immunity all provided near-complete protection against severe disease. Interpretation: Previous infection, any hybrid immunity, and two-dose vaccination all provided substantial protection against symptomatic and severe COVID-19 through the early Delta period. Thus, as a surrogate for natural infection, vaccination remains the safest approach to protection. Funding: National Institutes of Health
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