4 research outputs found
To Investigate and Fabricate Melt Processed Biomaterials Exhibiting Shape Recovery Properties
The purpose of this research was to produce and characterise novel hybrid biomaterials. Currently, there is a research gap in the area of producing hybrid biomaterials with shape memory properties for use in the fields of bioengineering or biomedical devices. This research will provide the initial results for a novel hybrid biomaterial that could be further researched for use in a biomedical device. In this study, melt extrusion methods were applied to the hybrid polymers. Three characterisation methods were employed within this work: mechanical (tensile) testing, shape recovery, and in vitro (trypsin) degradation. Across the three characterisation methods, PCL:PLA 30:70WT% 20% PEG-200 plasticised hybrid fibres were found to outperform the other materials reported in this thesis. Three key findings resulted from this research. The melt extrusion method used proved to be successful. PCL:PLA hybrid fibres could be produced consistently. Both glycerol and PEG-200 plasticisers used within this work were found to improve the blend properties of the hybrids. A total of 65% of tested hybrid fibres exhibited shape recovery when tested at a temperature of 37.5°C. The overall results of this study indicate that the hybrid materials produced here need to undergo further testing prior to use in biomedical applications
To Investigate and Fabricate Melt Processed Biomaterials Exhibiting Shape Recovery Properties
The purpose of this research was to produce and characterise novel hybrid biomaterials. Currently, there is a research gap in the area of producing hybrid biomaterials with shape memory properties for use in the fields of bioengineering or biomedical devices. This research will provide the initial results for a novel hybrid biomaterial that could be further researched for use in a biomedical device. In this study, melt extrusion methods were applied to the hybrid polymers. Three characterisation methods were employed within this work: mechanical (tensile) testing, shape recovery, and in vitro (trypsin) degradation. Across the three characterisation methods, PCL:PLA 30:70WT% 20% PEG-200 plasticised hybrid fibres were found to outperform the other materials reported in this thesis. Three key findings resulted from this research. The melt extrusion method used proved to be successful. PCL:PLA hybrid fibres could be produced consistently. Both glycerol and PEG-200 plasticisers used within this work were found to improve the blend properties of the hybrids. A total of 65% of tested hybrid fibres exhibited shape recovery when tested at a temperature of 37.5°C. The overall results of this study indicate that the hybrid materials produced here need to undergo further testing prior to use in biomedical applications