The rural non-farm economy in India: a review of the literature

This literature review was conducted as part of a policy-oriented research programme that aims to inform the development of pro-poor policy on the rural non-farm economy (RNFE). This literature review represents the first phase of the India work. The literature reviewed largely assesses the national significance of the RNFE based on the decennial Census and NSS employment data, which include workforce and enterprise data. It is argued that the RNFE is grossly underestimated because of a failure to capture the diversity of rural employment and misrepresentation of female labour

Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73.

The adoptive transfer of regulatory T-cells (Tregs) is a promising therapeutic approach in transplantation and autoimmunity. However, because large cell numbers are needed to achieve a therapeutic effect, in vitro expansion is required. By comparing their function, phenotype and transcriptomic profile against ex vivo Tregs, we demonstrate that expanded human Tregs switch their metabolism to aerobic glycolysis and show enhanced suppressive function through hypoxia-inducible factor 1-alpha (HIF1A) driven acquisition of CD73 expression. In conjunction with CD39, CD73 expression enables expanded Tregs to convert ATP to immunosuppressive adenosine. We conclude that for maximum therapeutic benefit, Treg expansion protocols should be optimised for CD39/CD73 co-expression

CM-Path Molecular Diagnostics Forum-consensus statement on the development and implementation of molecular diagnostic tests in the United Kingdom.

BACKGROUND: Pathology has evolved from a purely morphological description of cellular alterations in disease to our current ability to interrogate tissues with multiple 'omics' technologies. By utilising these techniques and others, 'molecular diagnostics' acts as the cornerstone of precision/personalised medicine by attempting to match the underlying disease mechanisms to the most appropriate targeted therapy. METHODS: Despite the promises of molecular diagnostics, significant barriers have impeded its widespread clinical adoption. Thus, the National Cancer Research Institute (NCRI) Cellular Molecular Pathology (CM-Path) initiative convened a national Molecular Diagnostics Forum to facilitate closer collaboration between clinicians, academia, industry, regulators and other key stakeholders in an attempt to overcome these. RESULTS: We agreed on a consensus 'roadmap' that should be followed during development and implementation of new molecular diagnostic tests. We identified key barriers to efficient implementation and propose possible solutions to these. In addition, we discussed the recent reconfiguration of molecular diagnostic services in NHS England and its likely impacts. CONCLUSIONS: We anticipate that this consensus statement will provide practical advice to those involved in the development of novel molecular diagnostic tests. Although primarily focusing on test adoption within the United Kingdom, we also refer to international guidelines to maximise the applicability of our recommendations

Surface tension : water and agrarian change in a rainfed village, West Bengal, India

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Journeying to live: A Journey with Seasonal Migrant Workers in Eastern India

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Seasonal Migration and Welfare/Illfare in Eastern India: A Social Analysis

Over 500,000 people are regularly engaged in seasonal migration for rice work into southern West Bengal. This paper analyses social processes at work in the interactions between employers and workers, and the welfare/illfare outcomes. Group identities based on religion and ethnicity are strengthened through the experience of migration and deployed by some migrants to make this form of employment less degrading. In West Bengal seasonal migration can involve practical welfare gains. Importantly, an informal wage floor has been put into place and managed by the peasant union allied to the largest party in the Left Front regime. However, the costs and risks of migration remain high

Seasonal Migration, Social Change and Migrants? Rights: Lessons from West Bengal

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Working Paper T27

Black R, Dominic K, Skeldon R, Murata A, Coppard D, Schmidt-Verkerk K. Demographics and Climate Change: Future Trends and their Policy Implications for Migration. Brighton, UK: Development Research Centre on Migration, Globalisation and Poverty; 2008

Seasonal migration, employer-worker interactions, and shifting ethnic identities in contemporary West Bengal

This article tells of changing social and spatial identities in the countryside of con temporary West Bengal. It draws on a study of interactions between those seeking wage work in agriculture and the people trying to recruit them. We find a continuing and nested process of both self-identification and categorisation. Unconscious as well as conscious ethnic affinities are consolidated and changed. At the same time, identities are used instrumentally by workers to make the outcome of negotiations less demeaning, and by employers to bargain more effectivelyfor the workforce they need. The context is one of the emergence of capitalist production relations in agriculture, presided over by a coalition government led by the Communist Party of India (Marxist). The newly pros perous agriculture has been a source of wealth for capitalist employers, reinforcing constructions of difference in relation to the migrant workers they employ. At the same time, many employers are attracted by the prospects of urban,jobs and life-styles and invest in their children's education. Migrant workers show a similar ambivalence, being attracted by the potential earnings and consumption possibilities arising out of being employed in the West Bengal 'rice bowl', and simultaneously repelled by the dangers they associate with the place