45,265 research outputs found
Improving Term Extraction with Terminological Resources
Studies of different term extractors on a corpus of the biomedical domain
revealed decreasing performances when applied to highly technical texts. The
difficulty or impossibility of customising them to new domains is an additional
limitation. In this paper, we propose to use external terminologies to
influence generic linguistic data in order to augment the quality of the
extraction. The tool we implemented exploits testified terms at different steps
of the process: chunking, parsing and extraction of term candidates.
Experiments reported here show that, using this method, more term candidates
can be acquired with a higher level of reliability. We further describe the
extraction process involving endogenous disambiguation implemented in the term
extractor YaTeA
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Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium.
Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and molecular subtypes of glioma at diagnosis. However, gliomas undergo significant cellular and molecular evolution during disease progression. We review the current knowledge on the genomic and epigenetic abnormalities in primary tumors and after disease recurrence, highlight the gaps in the literature, and elaborate on the need for a new multi-institutional effort to bridge these knowledge gaps and how the Glioma Longitudinal Analysis Consortium (GLASS) aims to systemically catalog the longitudinal changes in gliomas. The GLASS initiative will provide essential insights into the evolution of glioma toward a lethal phenotype, with the potential to reveal targetable vulnerabilities and, ultimately, improved outcomes for a patient population in need
Newsletter of the LowInputBreeds project. Issue 4. EU project LowInputBreeds - Development of integrated livestock breeding and management strategies to improve animal health, product quality and performance in European organic and ‘low input’ milk, meat and egg production
The fourth newsletter of the LowInputBreeds project reports on the successful first project symposium which took place in March in Wageningen, the Netherlands, focussing on ethical issues in animal breeding. Furthermore the newsletter contains an article on small ruminant production systems in Crete, and the traits required in order to improve production efficiency and product quality in traditional low-input dairy sheep production systems. And like every newsletter, we report progress in the four LowInputBreeds subprojects.
Already now we would like to draw your attention to the next LowInputBreeds conference, which will take place in spring 2012 in Tunisia. More information is available in the last page of this newsletter and updates will be posted at the project website www.lowinputbreeds.org. Please also note that in June 2011 the course "Genomic Selection in Livestock" will take place in Davos, Switzerland, one of the LowInputBreeds workshops for early stage researchers and agricultural advisors/technologists to facilitate an exchange of ideas/opinions and know-how and encourage potential future collaboration.
Finally we would like to announce Carlo Leifert has handed over project coordination responsibility to Gillian Butler, also from Newcastle University. She is not new to the project – she is responsible for work package 1.2 on the development of improved cross-breeding strategies
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Sparse whole-genome sequencing identifies two loci for major depressive disorder.
Major depressive disorder (MDD), one of the most frequently encountered forms of mental illness and a leading cause of disability worldwide, poses a major challenge to genetic analysis. To date, no robustly replicated genetic loci have been identified, despite analysis of more than 9,000 cases. Here, using low-coverage whole-genome sequencing of 5,303 Chinese women with recurrent MDD selected to reduce phenotypic heterogeneity, and 5,337 controls screened to exclude MDD, we identified, and subsequently replicated in an independent sample, two loci contributing to risk of MDD on chromosome 10: one near the SIRT1 gene (P = 2.53 × 10(-10)), the other in an intron of the LHPP gene (P = 6.45 × 10(-12)). Analysis of 4,509 cases with a severe subtype of MDD, melancholia, yielded an increased genetic signal at the SIRT1 locus. We attribute our success to the recruitment of relatively homogeneous cases with severe illness
The Modified-Classroom Observation Schedule to Measure Intentional Communication (M-COSMIC): Evaluation of reliability and validity
The Modified – Classroom Observation Schedule to Measure Intentional Communication (M-COSMIC) was developed as an ecologically valid measure of social-communication behaviour, delineating forms, functions, and intended partners of children’s spontaneous communication acts. Forty one children with autism spectrum disorder (ASD) aged 48 to 73 months were filmed within small-group settings at school. Communication behaviours during a five-minute teacher-led activity and a 10-minute free play session were coded from video-tape. Inter-rater reliability was high. Many M-COSMIC codes were significantly associated as predicted with Social and Communication domain scores on the Autism Diagnostic Observation Schedule (ADOS) and with scores on standardised language assessments. Agreement was more variable, however, at the level of individual M-COSMIC codes and ADOS items. Higher rates of responding, compliance behaviours and following pointing gestures and gaze occurred during the more structured teacher-led activity, compared to the free play. Results demonstrate preliminary construct validity of the M-COSMIC, showing its potential to describe and evaluate spontaneous social-communication skills in young children with ASD for research and applied purposes
Worker Rights Consortium Remediation Report re Lianglog Socks Co. Ltd (China)
WRC report on the efforts to remediate violations previously found at Lianglong Socks, a producer of hosiery for RJ McCarthy Ltd, a supplier of school uniforms. Describes persistence of labor violations and finds that RJ McCarthy is not responsible due to their lack of influence in the matter
Worker Rights Consortium Assessment re Jerzees Choloma (Honduras): Report of Findings and Recommendations
WRC report on its assessment of labor violations at the Jerzees Choloma factory in Honduras. Includes a description of evidence and assessment logistics, and recommendations for remedial action to be taken by the company
Factory Case Update: Thai Garment Export (Thailand)
Case_Summary___Thai_Garment_Export_011210_proofed.pdf: 223 downloads, before Oct. 1, 2020
WRC Factory Assessment LTU Apparel (Thailand): Findings, Recommendations and Status Report
WRC_Report___LTU_Apparel_0810.pdf: 241 downloads, before Oct. 1, 2020
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