Le rôle du récepteur scavenger B type I, SR-BI, dans l'absorption et le métabolisme du cholestérol au niveau intestinal

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal

Mapping Future Trends in Integrated Reporting, CSR and Business Sustainability Research: A Cluster-based Approach

This paper aims to investigate the dependence and independence between the variables inferred in the bibliometric analysis of the literature on corporate social responsibility (CSR), business sustainability (BS), and integrated reporting (IR). In this paper, we undertook a bibliometric analysis with statistical analysis to fulfill the proposed goal, based on scientific papers from 1975 to 2021 indexed by ISI Web of Science and SCOPUS databases on the abovementioned topics. The results are the development of a model for mapping future research directions on IR, CSR, and BS issues using the clustering method. The bibliometric and statistical analysis can help researchers by providing clear guidelines for future studies, depending on the behaviour of research clusters on the IR topic. Previous studies didn’t attempt to analyze future research directions of IR from a bibliometric and statistical standpoint, which should be carefully tracked, because IR can offer support to companies by improving their communication with stakeholders

Joint damage progression in patients with rheumatoid arthritis in clinical remission. Do biologics perform better than synthetic antirheumatic drugs?

Randomized controlled studies have demonstrated protective advantages of biologic therapies over the synthetic disease-modifying antirheumatic drugs (DMARD) in slowing joint damage progression in patients with rheumatoid arthritis (RA). This effect appears to be largely independent of the clinical disease control. We measured the rate of radiographic progression in patients with RA in clinical remission treated with synthetic versus biologic DMARD

Structural and Behaviour Optimization of Tubular Structures Made of Tailor Welded Blanks by Applying Taguchi and Genetic Algorithms Methods

Even though they initially appeared as a method of using waste from other production processes, tailored welded blanks (TWB) presented several advantages by combining materials with different characteristics. On the one hand, this study focuses on minimizing the adverse effects caused by the springback of TWB parts. The proposed method is based on the Taguchi technique using orthogonal type 23 networks. On the other hand, genetic algorithms were applied to obtain maximum performance parameters within the dynamic loadings of tubular structures made of TWB by advantageous positioning of the weld line. The obtained data were compared and evaluated through software platforms such as MATLAB, Design Expert, and Dynaform, and experimental validation. By generating an objective function, the construction of thin-walled tubular structures can be controlled for a predetermined deformation and maximum energy absorption. The data obtained has an error rate of less than 3%, thus considering that this method can be used successfully in the qualitative and quantitative estimation of dynamically loaded TWB tubular structures

Differential Protective Effect of Zinc and Magnesium for the Hepatic and Renal Toxicity Induced by Acetaminophen and Potentiated with Ciprofloxacin in Rats

Background and Objectives: The purpose of this study was to investigate the influence induced by magnesium chloride (MgCl2) and zinc gluconate (ZnG) supplementation on liver and kidney injuries experimentally induced with acetaminophen (AAPh) and potentiated by a ciprofloxacin addition in rats. Material and Methods: The experiment was performed on five animal groups: group 1—control, treated for 6 weeks with normal saline, 1 mL/kg; group 2—AAPh, treated for 6 weeks with AAPh, 100 mg/kg/day; group 3—AAPh + C, treated for 6 weeks with AAPh 100 mg/kg/day and ciprofloxacin 50 mg/kg/day, only in the last 14 days of the experiment; group 4—AAPh + C + Mg, with the same treatment as group 3, but in the last 14 days, MgCl2 10 mg/ kg/day was added; and group 5—AAPh + C + Zn, with the same treatment as group 3, but in the last 14 days, zinc gluconate (ZnG), 10 mg/kg/day was added. All administrations were performed by oral gavage. At the end of the experiment, the animals were sacrificed and blood samples were collected for biochemistry examinations. Results: Treatment with AAPh for 6 weeks determined an alteration of the liver function (increases in alanine aminotransferase, aspartate aminotransferase, lactic dehydrogenase, and gamma-glutamyl transferase) and of renal function (increases in serum urea and creatinine) (p p p p 2 provided a slight protection against the increase in liver enzymes, and a more pronounced protection against the increase in serum urea and creatinine (0.001 p 2 provided a slight protection against the decrease in superoxide dismutase (0.01 p p Conclusions: This study presents further proof for the beneficial effect of magnesium and zinc salts against toxicity induced by different agents, including antibacterials added to the analgesic and antipyretic acetaminophen; the protection is proven on the liver and kidney’s function, and the antioxidant profile improvement has a key role, especially in the case of zinc gluconate

Exploitation of fishing resources in Suceava county: Profitability analysis (Rb/T) of specialized farms in a mountainous region

Aquaculture is an economic sector that has rapidly grown in recent years, due to European programs and the support provided for this activity. Given this accelerated development and the attention this sector receives on an international level, this paper focuses on identifying the growth factors in the sector and highlighting certain general aspects of its development in Romania, followed by an analysis of the available data on the exploitation of fishing resources in Suceava County in terms of performance

Financial sustainability of oil and gas companies—basis for building resilience strategies

The crisis situations that have affected the oil and gas market have had a significant impact on the companies’ performance from this sector and especially on their customers. In these circumstances, many companies faced increasing difficulties and in some cases, in order to survive, they had to restructure their business or even leave the market. Considering this context, this kind of situations are also manifesting in Romania where we can identify companies facing the erosion of their competitive position, with economic, financial and capital consequences, while other companies still managed to react positively to the crisis generated by the energy sector through innovation and internationalization. This article analyses the sustainability of the operational activity of oil and gas extraction companies from Romania, based on financial and economic data and information, having the aim of investigating the way in which the performance of different markets has influenced the economic and financial results and consequently, the implications of this influence for the structure of the activity and on the financial-economic sustainability. The research methodology is specific to a quantitative research, based on a sample of financial and economic data reported by all 29 oil and gas extraction companies from Romania over the period of 2008–2022. The data collected from the financial reports formed the basis for the calculation of the financial indicators and ratios considered relevant in forecasting the economic and financial sustainability of these companies. The results obtained are materialised in the development of a model whose aim is to assess the financial and economic sustainability, its independent variables being grouped into performance, activity and risk indicators. The usefulness of the results obtained is relevant both for the companies concerned and for their customers and suppliers who will show a visible dependence on energy costs, but also for investors and financiers directly interested in performance and sustainability information, on the basis of which they will determine the value of their own economic benefits