1,504 research outputs found

    Reading and writing genomes

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    Seasonal cycling of sulfur and iron in porewaters of a Delaware salt marsh

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    An extensive pore water data set has been gathered in the Great Marsh, Delaware over various seasons, salinities, and tides. The data all point to a complimentary redox cycle for sulfur and iron which operates seasonally and tidally. Surface oxidizing conditions prevail in summer, with more reducing conditions at depth during the winter. During the spring tides which flood the marsh, pyrite oxidation occurs releasing excess dissolved iron (II) and sulfate to the porewaters, and precipitating authigenic solid iron phases. The redox conditions in the porewaters of the upper zone during the summer is poised between mildly oxidizing and mildly reducing conditions as shown by pE calculations. This redox environment and intermediate iron-sulfur redox species may be important for the stimulation of plant growth (photosynthesis) and sustenance of a viable microbial community (heterotrophy and chemoautropy)

    Notes and Comments: The Right to a Speedy Trial in Maryland

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    In the wake of the Supreme Court\u27s 1972 decision in Barker v. Wingo, Maryland appellate courts have enforced more rigorously the right of criminal defendants to a speedy trial. This article surveys the application and treatment of the Barker criteria by the Maryland courts in recent decisions

    Notes and Comments: The Right to a Speedy Trial in Maryland

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    In the wake of the Supreme Court\u27s 1972 decision in Barker v. Wingo, Maryland appellate courts have enforced more rigorously the right of criminal defendants to a speedy trial. This article surveys the application and treatment of the Barker criteria by the Maryland courts in recent decisions

    Reading and writing omes

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    A Dynamic Programming Approach to De Novo Peptide Sequencing via Tandem Mass Spectrometry

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    The tandem mass spectrometry fragments a large number of molecules of the same peptide sequence into charged prefix and suffix subsequences, and then measures mass/charge ratios of these ions. The de novo peptide sequencing problem is to reconstruct the peptide sequence from a given tandem mass spectral data of k ions. By implicitly transforming the spectral data into an NC-spectrum graph G=(V,E) where |V|=2k+2, we can solve this problem in O(|V|+|E|) time and O(|V|) space using dynamic programming. Our approach can be further used to discover a modified amino acid in O(|V||E|) time and to analyze data with other types of noise in O(|V||E|) time. Our algorithms have been implemented and tested on actual experimental data.Comment: A preliminary version appeared in Proceedings of the 11th Annual ACM-SIAM Symposium on Discrete Algorithms, pages 389--398, 200
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