Identifying the Service Quality for a B2B Cross-Border E-Commerce Platform

The global cross-border e-commerce (CBEC) transactions is experiencing a fast development in recent years. However, the academic research is still rare. In addition, service quality of the CBEC platforms have been identified as the important factors of the success of CBEC but there is a lack of empirical work to identify the service quality of the business to business (B2B) CBEC platforms are rare. To fulfill this gap, this study intends to identify the critical service quality of the B2B CBEC platform. Based on the service quality model, we will identify the critical service quality of the B2B CBEC platform. We will conduct a modified Delphi method to collect data with the experts and suppliers in the platform. Our research findings will contribute to the academia by creating a service quality model of B2B CBEC platform. The results will provide practical insights for the platform design of B2B CBEC platform

Endoscopic Balloon Dilatation for Esophageal Strictures in Children Younger Than 6 Years: Experience in a Medical Center

Esophageal strictures in children may be caused by congenital anomaly, caustic agent or foreign body ingestion, complication of reflux esophagitis, and after esophageal surgery. Accidental ingestion of alkaline fluid is the most common cause of corrosive esophagitis in children in Taiwan. In this article, we studied 10 pediatric patients who had esophageal strictures and required endoscopic balloon dilatation (EBD) therapy under general anesthesia from January 2003 to June 2009. The median age of the studied children who received their first EBD treatment was 36.2 months (13.4–60.9 months), with a dilator size of 8.0mm (5–12 mm). The interval between injury and initial EBD was 3.0 months (1.3–60.8 months). The treatment duration averaged 16.7 months (3.0–69.3 months), with 13.5 (4–31) instances of EBD therapy per patient. The greater the length of stricture, the more number of times EBD was needed. In these cases, no severe complication was found after the procedure. The result indicated that EBD under general anesthesia was a safe and effective method to resolve the symptom of dysphagia and diet condition. Because of the limited number of study cases, long-term studies are required to further confirm the clinical effect of EBD under general anesthesia

MetaSquare: An integrated metadatabase of 16S rRNA gene amplicon for microbiome taxonomic classification

MOTIVATION: Taxonomic classification of 16S ribosomal RNA gene amplicon is an efficient and economic approach in microbiome analysis. 16S rRNA sequence databases like SILVA, RDP, EzBioCloud and HOMD used in downstream bioinformatic pipelines have limitations on either the sequence redundancy or the delay on new sequence recruitment. To improve the 16S rRNA gene-based taxonomic classification, we merged these widely used databases and a collection of novel sequences systemically into an integrated resource. RESULTS: MetaSquare version 1.0 is an integrated 16S rRNA sequence database. It is composed of more than 6 million sequences and improves taxonomic classification resolution on both long-read and short-read methods. AVAILABILITY AND IMPLEMENTATION: Accessible at https://hub.docker.com/r/lsbnb/metasquare_db and https://github.com/lsbnb/MetaSquare. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online

Polymicrobial bloodstream infection involving Aeromonas species: Analysis of 62 cases

AbstractObjectiveTo better understand Aeromonas-involved polymicrobial bacteremia (AIPMB).Materials and MethodsWe conducted a retrospective analysis of patients with AIPMB admitted to three large referral hospitals in Taiwan between 2001 and 2008.ResultsOf a total of 62 patients with AIPMB, 22 had healthcare-associated infection and 40 had community-acquired infection. Enterobacteriaceae was the most common concurrent pathogen (82%). The leading underlying diseases/conditions in the affected patients were solid cancers (45%), recent gastric acid suppressant therapy (39%) and liver cirrhosis (26%). More than 95% of the Aeromonas isolates were susceptible to an aminoglycoside, a third- or fourth-generation cephalosporin, imipenem or ciprofloxacin. Antibiotic susceptibilities did not significantly differ between Aeromonas isolates in patients with healthcare-associated AIPMBs and those in patients with community-acquired AIPMBs. Coinfection with Enterobacteriaceae occurred more commonly in community-acquired AIPMB (93% vs. 64%; p=0.012).ConclusionsAIPMB occurred commonly in patients with liver cirrhosis, solid cancers or recent gastric acid suppressant therapy. Enterobacteriaceae were the most common concurrent pathogens. Similar antibiotic profiles were found in Aeromonas isolates of healthcare-associated and community-acquired AIPMBs

Evaluation of Intrarenal Blood Flow by Doppler Ultrasonography Immediately after Extracorporeal Shock Wave Lithotripsy on Hydronephrotic Kidney

Extracorporeal shock wave lithotripsy (ESWL) is an effective and relatively noninvasive mode of treatment for urinary calculi. The aim of this study was to test whether therapeutic ESWL induces changes in renal parenchymatous blood flow and to evaluate shock wave side effects on the renal parenchyma. A total of 45 patients who underwent ESWL for ureteropelvic stone between January 2002 and July 2003 were included in this prospective study. Color Doppler sonography before and 30 minutes after ESWL showed no significant morphologic change. Resistive index (RI) was used to estimate renovascular resistance. The RI significantly increased in obstructed hydronephrotic kidneys. However, no significant change was observed in both treated and untreated kidneys before and after treatment. Hydronephrotic kidneys do not have a higher risk of post-ESWL renovascular resistance interference. The measurement of changes in RI with Doppler ultrasonography may provide useful information for clinical diagnosis of renal tubulointerstitial and vascular damage

UNIT project: Universe NN-body simulations for the Investigation of Theoretical models from galaxy surveys

We present the UNIT $N$-body cosmological simulations project, designed to provide precise predictions for nonlinear statistics of the galaxy distribution. We focus on characterizing statistics relevant to emission line and luminous red galaxies in the current and upcoming generation of galaxy surveys. We use a suite of precise particle mesh simulations (FastPM) as well as with full $N$-body calculations with a mass resolution of $\sim 1.2\times10^9\,h^{-1}$M$_{\odot}$ to investigate the recently suggested technique of Angulo & Pontzen 2016 to suppress the variance of cosmological simulations We study redshift space distortions, cosmic voids, higher order statistics from $z=2$ down to $z=0$. We find that both two- and three-point statistics are unbiased. Over the scales of interest for baryon acoustic oscillations and redshift-space distortions, we find that the variance is greatly reduced in the two-point statistics and in the cross correlation between halos and cosmic voids, but is not reduced significantly for the three-point statistics. We demonstrate that the accuracy of the two-point correlation function for a galaxy survey with effective volume of 20 ($h^{-1}$Gpc)$^3$ is improved by about a factor of 40, indicating that two pairs of simulations with a volume of 1 ($h^{-1}$Gpc)$^3$ lead to the equivalent variance of $\sim$150 such simulations. The $N$-body simulations presented here thus provide an effective survey volume of about seven times the effective survey volume of DESI or Euclid. The data from this project, including dark matter fields, halo catalogues, and their clustering statistics, are publicly available at http://www.unitsims.org.Comment: 12 pages, 9 figures. This version matches the one accepted by MNRAS. The data from this project are publicly available at: http://www.unitsims.or

Covariance matrices for variance-suppressed simulations

Cosmological $N$-body simulations provide numerical predictions of the structure of the universe against which to compare data from ongoing and future surveys. The growing volume of the surveyed universe, however, requires increasingly large simulations. It was recently proposed to reduce the variance in simulations by adopting fixed-amplitude initial conditions. This method has been demonstrated not to introduce bias in various statistics, including the two-point statistics of galaxy samples typically used for extracting cosmological parameters from galaxy redshift survey data. However, we must revisit current methods for estimating covariance matrices for these simulations to be sure that we can properly use them. In this work, we find that it is not trivial to construct the covariance matrix analytically, but we demonstrate that EZmock, the most efficient method for constructing mock catalogues with accurate two- and three-point statistics, provides reasonable covariance matrix estimates for variance-suppressed simulations. We further investigate the behavior of the variance suppression by varying galaxy bias, three-point statistics, and small-scale clustering.Comment: 9 pages, 7 figure

Emerged HA and NA Mutants of the Pandemic Influenza H1N1 Viruses with Increasing Epidemiological Significance in Taipei and Kaohsiung, Taiwan, 2009–10

The 2009 influenza pandemic provided an opportunity to observe dynamic changes of the hemagglutinin (HA) and neuraminidase (NA) of pH1N1 strains that spread in two metropolitan areas -Taipei and Kaohsiung. We observed cumulative increases of amino acid substitutions of both HA and NA that were higher in the post–peak than in the pre-peak period of the epidemic. About 14.94% and 3.44% of 174 isolates had one and two amino acids changes, respective, in the four antigenic sites. One unique adaptive mutation of HA2 (E374K) was first detected three weeks before the epidemic peak. This mutation evolved through the epidemic, and finally emerged as the major circulated strain, with significantly higher frequency in the post-peak period than in the pre-peak (64.65% vs 9.28%, p<0.0001). E374K persisted until ten months post-nationwide vaccination without further antigenic changes (e.g. prior to the highest selective pressure). In public health measures, the epidemic peaked at seven weeks after oseltamivir treatment was initiated. The emerging E374K mutants spread before the first peak of school class suspension, extended their survival in high-density population areas before vaccination, dominated in the second wave of class suspension, and were fixed as herd immunity developed. The tempo-spatial spreading of E374K mutants was more concentrated during the post–peak (p = 0.000004) in seven districts with higher spatial clusters (p<0.001). This is the first study examining viral changes during the naïve phase of a pandemic of influenza through integrated virological/serological/clinical surveillance, tempo-spatial analysis, and intervention policies. The vaccination increased the percentage of E374K mutants (22.86% vs 72.34%, p<0.001) and significantly elevated the frequency of mutations in Sa antigenic site (2.36% vs 23.40%, p<0.001). Future pre-vaccination public health efforts should monitor amino acids of HA and NA of pandemic influenza viruses isolated at exponential and peak phases in areas with high cluster cases