Green Thumbs Incorporated: A business plan on transplant

Executive Summary. Green Thums Incorporated is a corporation that is organized to create new and innovative products like Transplant to satisfy the needs of the consumers. The business address of the corporation is at 99-C Jose Abad Santos St., Bayview Village, Parañaque City. Transplant is a unique and innovative product that uses gel (from organic materials) instead of the common soil. The gel it uses is made of 100% non-toxic, biodegradable, odorless crystals that saves watering by 90%. The primary market of Transplant includes both schools and households namely, College of St. Benilde, St. Benedict\u27s College, Bayview Village, Cityland Megaplaza and Fortunata Village. The primary market has a total population of (N=13,290) with 11050 students and 2240 residents of the respective households. A sample size of 266 respondents was obtained using the Systematic Random Sampling. A survey questionnaire was distributed among the primary market and after the completion, the proponents were able to gather data and analyzed them. Based on the survey, 76% of the respondents find Transplant unique and majority of the respondents (91%) are willing to buy the product. The monthly potential demand was computed to be 1275 units and the market share is 68.07%. Through the time and motion study the proponents was able to conclude that the Assembly Line Method is the more operative way of producing the product. In one production day, an average of 217 units of the product can be produced. Minimum output is 115 units while maximum output is 319 units of the product Transplant per day. Cycle time for the production of one unit of Transplant is 47 minutes. Production Cost per unit was computed to be 38.00 per unit. The selling price of the product was also computed to be P79.00 per unit with a mark up of 51.94%. The Break-even analysis presented that Green Thumbs Incorporated needs to sell more or less 583 units of Transplant or attain gross profit of P 172,744.72 to avoid incurring losses. The type of business ownership that the proponents chose was corporation. The corporate name Green Thumbs Incorporated was selected because the proponents are believed to be good in taking care of plants and are very gifted. The corporation will operate for ten (10) months. The Board of Directors of the company are the stockholders as well. Each of the proponents have the duties and responsibilities to observe. From the requirement of the business management department, no liabilities shall be allowance or through the help of their parents. The project cost required to finance the first month of operation is P 38,000. Projected financial statements are also provided to show the expected income and the assets of the corporation. It is projected that the business will generate an income of P 151,523.17 at the end of existence. It will have a total assets amounting to 189,057.16. The return on investment is 399% while the return on equity is 80.15%. Clearly, the business is very profitable. Green Thumbs Incorporated has prepared for incoming risks by creating and implementing measures that will either prevent it or solve it once problems arise from it. Control measures were also put up to ensure the fulfillment of the company\u27s goals. In conclusion, the study that the proponents made presented that the project was viable and accepted in the market. However, the proponents still should take into consideration the risks that the company might encounter during the actual business operation such as peso devaluation, inflation and economic crisis. Being open to improvements will surely make the company more efficient and effective

The outcomes of patients with diabetes mellitus in The Philippine CORONA Study

Patients diagnosed with diabetes mellitus (DM) who are infected with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) belong to the most vulnerable patient subgroups. Emerging data has shown increased risks of severe infections, increased in ICU admissions, longer durations of admission, and increased mortality among coronavirus disease 2019 (COVID-19) patients with diabetes. We performed a subgroup analysis comparing the outcomes of patients diagnosed with DM (n = 2191) versus patients without DM (n = 8690) on our data from our study based on a nationwide, comparative, retrospective, cohort study among adult, hospitalized COVID-19 patients involving 37 hospital sites from around the Philippines. We determined distribution differences between two independent samples using Mann–Whitney U and t tests. Data on the time to onset of mortality, respiratory failure, intensive care unit (ICU) admission were used to build Kaplan–Meier curves and to compute for hazard ratios (HR). The odds ratios (OR) for longer ventilator dependence, longer ICU stay, and longer hospital stays were computed via multivariate logistic regression. Adjusted hazard ratios (aHR) and ORs (aOR) with 95% CI were calculated. We included a total of 10,881 patients with confirmed COVID-19 infection (2191 have DM while 8690 did not have DM). The median age of the DM cohort was 61, with a female to male ratio of 1:1.25 and more than 50% of the DM population were above 60 years old. The aOR for mortality was significantly higher among those in the DM group by 1.46 (95% CI 1.28–1.68; p \u3c 0.001) as compared to the non-DM group. Similarly, the aOR for respiratory failure was also significantly higher among those in the DM group by 1.67 (95% CI 1.46–1.90). The aOR for developing severe COVID-19 at nadir was significantly higher among those in the DM group by 1.85 (95% CI 1.65–2.07; p \u3c 0.001). The aOR for ICU admission was significantly higher among those in the DM group by 1.80 (95% CI 1.59–2.05) than those in the non-DM group. DM patients had significantly longer duration of ventilator dependence (aOR 1.33, 95% CI 1.08–1.64; p = 0.008) and longer hospital admission (aOR 1.13, 95% CI 1.01–1.26; p = 0.027). The presence of DM among COVID-19 patients significantly increased the risk of mortality, respiratory failure, duration of ventilator dependence, severe/critical COVID-19, ICU admission, and length of hospital stay

Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

Background Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)