20 research outputs found

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    ONU Scholar Week #2

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    Telos: The Destination for Nazarene Higher Education

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    A collection of essays that attempts to articulate the common “center pole” around which Nazarene higher educators stand and the theological and pedagogical commitments that draw them together. An end product of the Pole Project, the volume is a values document for Nazarene educational institutions and was produced and reviewed by 51 faculty at 16 institutions from six countries. The title, Telos, comes from the Greek term used in the New Testament to address the perfect end, or destination, for which Christians are designed. We achieve this when we are perfectly aimed by God. Each contribution in the collection discusses where Nazarene higher education is headed and seeks to explain why the end goal of Nazarene education is unique. The volume is organized into three sections. The first provides theological and epistemological foundations. The second illustrates how those commitments are applied to particular academic disciplines. Finally, four Nazarene educators from various parts of the world balance these North American views with cultural commentary.https://digitalcommons.olivet.edu/acaff_books/1000/thumbnail.jp

    Telos: The Destination for Nazarene Higher Education

    Get PDF
    A collection of essays that attempts to articulate the common “center pole” around which Nazarene higher educators stand and the theological and pedagogical commitments that draw them together. An end product of the Pole Project, the volume is a values document for Nazarene educational institutions and was produced and reviewed by 51 faculty at 16 institutions from six countries. The title, Telos, comes from the Greek term used in the New Testament to address the perfect end, or destination, for which Christians are designed. We achieve this when we are perfectly aimed by God. Each contribution in the collection discusses where Nazarene higher education is headed and seeks to explain why the end goal of Nazarene education is unique. The volume is organized into three sections. The first provides theological and epistemological foundations. The second illustrates how those commitments are applied to particular academic disciplines. Finally, four Nazarene educators from various parts of the world balance these North American views with cultural commentary.https://digitalcommons.olivet.edu/acaff_books/1000/thumbnail.jp

    Intoxicação experimental por monofluoroacetato de sódio em bovinos: aspectos clínicos e patológicos

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    Monofluoracetato de sódio (MF) foi identificado, por cromatografia, em três das doze plantas que causam morte súbita em bovinos no Brasil, incluindo Palicourea marcgravii, a mais importante desse grupo. Uma lesão considerada típica por alguns autores para intoxicação foi¹ a degeneração hidrópico-vacuolar dos túbulos uriníferos contorcidos distais (DHV). O objetivo deste trabalho foi verificar se a ingestão de MF induz sinais clínicos e lesões similares às observadas nos bovinos intoxicados pelas plantas que causam morte súbita. Seis vacas receberam, por via oral, 0,5 e 1,0mg/kg de MF diluídos em 50mL de água destilada. Clinicamente, os animais apresentaram taquicardia, jugular repleta com pulso venoso positivo, respiração abdominal, ligeira perda de equilíbrio, por vezes cambaleavam, deitavam e apoiavam a cabeça no flanco. Na fase final (agônica), todos os animais caíam em decúbito lateral, esticavam os membros, faziam movimentos de pedalagem, apresentavam opistótono, nistagmo, mugidos e a morte ocorria em 2-14 minutos. À necropsia verificaram-se aurículas, jugulares, ázigos e pulmonares moderadamente ingurgitadas. Observaram-se ainda leve a moderado edema da subserosa nos locais de fixação da vesícula biliar no fígado, além de leve edema entre o duodeno e o pâncreas. O exame histopatológico revelou, em todos os animais, desde leve a acentuada DHV das células epiteliais dos túbulos uriníferos contorcidos distais associada à cariopicnose. Com relação à ultraestrutura, observou-se vacuolização do citoplasma devido ao acúmulo de água. Vacuolização e necrose de coagulação individual ou de grupos de hepatócitos e leve congestão hepática secundários à estase venosa também foram observados. DHV tem sido observada em casos de envenenamento por outras substâncias, porém nestes não está restrita aos túbulos distais e não se observa cariopicnose. Este estudo demonstra que a DHV dos túbulos renais de bovinos pode ser causada pelo envenenamento por MF e, por analogia, essa substância deve ser considerada como um dos fatores importantes, senão o mais significativo, implicado na morte dos animais que ingerem plantas que causam morte súbita no Brasil. Isso indica que estudos, que envolvam metabolização de MF por bactérias ruminais, teriam grande aplicabilidade econômica, uma vez que pelo menos 500.000 bovinos morrem anualmente intoxicados por plantas do grupo das que causam morte súbita no Brasil.Sodium monofluoroacetate (MF) was identified, by cromatography, in three of the 12 plants that cause sudden death in cattle in Brazil, including Palicourea marcgravii, the most important plant of this group. A special kind of hydropic-vacuolar degeneration (HVD) of the distal convoluted uriniferous tubules was considered typical for the poisoning by some authors. The objective of this study was to verify if the ingestion of MF causes similar clinical signs and lesion in cattle poisoned by plants that cause sudden death. Six cows received orally 0.5 and 1.0mg/kg of M diluted in 50mL of distilled water. Clinically the animals presented tachycardia, engorgement and positive pulse of the jugular vein, abdominal breathing, swaying gait, subtle unbalance, and recumbency with head placed the on the flank. In the agonal phase all the animals in lateral recumbence presented muscular fasciculation, tonic contraction, peddling movements, opisthotonus, nystagmus, and died between 2 and 14 minutes. At postmortem examination, the heart auricles, jugular and pulmonary veins were moderately distended and engorged with blood. Slight to moderate edema of the subserosa was seen around the gall bladder and the duodenum near to the pancreas. At light microscopy, HVD associated with nuclear picnosis of the epithelial cells of the distal convoluted uriniferous tubules was present in all animals. Ultrastructurally, the cell lesion represents formation of cytosolic vacuoles, likely due to accumulation of water. Coagulation necrosis of individual or groups of hepatocytes and slight hepatic congestion secondary to the venous stasis were also observed. Hydropic-vacuolar degeneration has been observed in cases of poisoning by many substances, which cause acute tubular nephrosis, however not restricted to the distal renal tubules and without nuclear picnosis. This study demonstrates that the HVD in the kidney can be caused by MF and, in analogy, the compound should be considered responsible for the death of cattle that ingest toxic plants which cause sudden death in Brazil. Our results can be supportive to studies that will focus on the degradation of MF by rumen bacteria, what might have economic implications, as at least 500.000 cattle die annually by sudden death causing toxic plants in Brazil

    Non-profit and for-profit workers during organizational innovation :

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    The purpose is to apply the new ARFIMA methodology to distinguish between different models of long-run behavior i.e. nesting the difference stationary and trend stationary models. In particular, we analyze the long-term dynamic behavior of discreetly observed data at monthly and quarterly frequencies for the G-7 countries spanning the period from 1961 through 2000. First, in this dissertation fractional time series models are estimated using a relatively new maximum likelihood procedure (Li and McLeod, 1986; and Sowell, 1990b). Second, we provide some international evidence on persistence using post war data for the G-7 countries. Finally, the data set includes two output measures, two components of the gross domestic product (GDP), two measures of inflation, two measures of interest rates, a broad money stock measure and the real effective exchange rate

    Scholar Week

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    ONU\u27s Scholar Week flyer #3
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