Serum eosinophilic cationic protein is correlated with food impaction and endoscopic severity in eosinophilic esophagitis

Background/Aims: The aim of the present study was to analyze the diagnostic accuracy of serum eosinophilic cationic protein (ECP) for eosinophilic esophagitis (EoE) and the correlation of ECP with clinical, histopathological, laboratory, and endoscopic features of EoE. Materials and Methods: Fifteen patients with EoE and 14 healthy controls were included in the study. Demographic parameters were recorded. EoE Endoscopic Reference Score (EREFS) was calculated according to endoscopic features, and esophageal biopsies were obtained by a single experienced endoscopist in a patient group. Serum ECP levels (mu g/mL), absolute eosinophil count (U/mm(3)), and maximum peak of eosinophils/high-power field in esophageal biopsies were analyzed. Results: The median age of all participants was 33.0 (min-max: 18-46) years. There were 27 (93.1%) male patients. Serum ECP level was significantly higher in patients with EoE than in healthy volunteers (20.4 vs. 8.8, p<0.0001). According to the receiver operating characteristic (ROC) curve analysis, ECP had 80% sensitivity and 92.8% specificity to diagnose EoE with a cut-off value of 13.9 mu g/mL (area under the ROC curve 0.895; p<0.0001; 95% CI: 0.725-0.978). EREFS (p<0.0001) and the presence of food impaction (p=0.04) were significantly correlated with ECP. Conclusion: Serum ECP is an accurate non-invasive biomarker for EoE with high specificity and sensitivity. In addition, ECP is strongly correlated with EREFS and the symptom of food impaction

GERIATRI YAŞ GRUBUNDA GASTROINTESTINAL KANAMA VE TEDAVISI

Approximately 35%-40% of geriatric patients seek medical care for gastrointestinal symptoms at least once a year. At least 1% of the population aged over 80 years is hospitalized each year due to gastrointestinal hemorrhage. Gastrointestinal hemorrhage is frequently observed in this population and associated with high mortality and morbidity. Also, gastrointestinal hemorrhage is one of the main causes of hospitalization among geriatric patients. Geriatric patients with GIH constitute a subgroup of patients requiring special care in hospitals. The bleeding may occur in the upper or lower gastrointestinal tract and manifest itself with a variety of symptoms depending on its location. The incidence and natural course of hemorrhage are affected by antiplatelet and anticoagulant medications. The outcome of gastrointestinal hemorrhage in geriatric patients depends largely on the characteristics of bleeding lesion and comorbidities.Geriatri yaş grubundaki hastaların yaklaşık %35-40’lık bir kısmı, yılda en az 1 kez gastrointestinal semptomlar nedeni ile tıbbi yardıma ihtiyaç duymaktadır. Seksen yaş üstü nüfusun en az %1’i, her yıl gastrointestinal kanama nedeni ile hastaneye yatmak zorunda kalmaktadır. Gastrointestinal kanaması olan geriatric olgular, hastanelerde özel bakım gerektiren hasta grubunu oluşturmaktadır. Geriatrik çağda gastrointestinal kanama sık gözlenmektedir ve beraberinde yüksek morbidite ve mortalite riski taşımaktadır. Kanama üst veya alt gastrointestinal sistemden köken alabilir ve kanama lokalizasyonuna göre semptom çeşitliliği gösterebilmektedir. Kanamanın insidansı ve klinik seyri, hastanın kullandığı antiplatellet veya antikoagülan tedaviden etkilenmektedir. Geriatrik olgulardaki kanamanın seyri çoğunlukla kanayan lezyonun karakteristiğine ve eşlik eden hastalık olup olmamasına bağlıdır

Gastrointestinal hemorrhage and its management in geriatric age group

Approximately 35%-40% of geriatric patients seek medical care for gastrointestinal symptoms at least once a year. At least 1% of the population aged over 80 years is hospitalized each year due to gastrointestinal hemorrhage. Gastrointestinal hemorrhage is frequently observed in this population and associated with high mortality and morbidity. Also, gastrointestinal hemorrhage is one of the main causes of hospitalization among geriatric patients. Geriatric patients with GIH constitute a subgroup of patients requiring special care in hospitals. The bleeding may occur in the upper or lower gastrointestinal tract and manifest itself with a variety of symptoms depending on its location. The incidence and natural course of hemorrhage are affected by antiplatelet and anticoagulant medications. The outcome of gastrointestinal hemorrhage in geriatric patients depends largely on the characteristics of bleeding lesion and comorbidities

CONSIDERING THE INEFFICIENCIES IN LABOR MARKET FOR AN EXPLANATION OF MIGRATION FACT FROM RURAL TO URBAN AREAS IN TURKEY

In this study, it is intended to explain determinant points between market price of labor and shadow price of labor and explain migration from rural to urban according to this wage difference. Unemployment or rigidity in urban labor market causes different wage level from equilibrium wage level. This high level wage increases alternative cost of rural against urban and encourages migration from rural to urban. The state of instigating the migration from rural to urban that causing by the increase on wages levels which is in proportion to secession of competition level has been calculated by considering the Turkey example for different sectors. Consequently, it has been determined that the wage level modified according to the distortion in competition is one of the factors effecting the migration to rural to urban.Shadow Price; Migration from Rural to Urban; Labor Market

Siroz ve Sarkopeni

[No abstract availeble

Adhesive Fragment Reattachment after Orthodontic Extrusion: A Case Report

In the treatment of crown fractures, adhesive fragment reattachment provides a good alternative to other restorative techniques, offering several advantages. The present paper reports a case in which the treatment of a cervical crown fracture was accomplished by reattaching the tooth fragment with a flowable resin composite. Orthodontic root extrusion was performed with a modified Hawley appliance prior to fragment reattachment. The clinical and radiographic results after 2.5 years were successful

Processing of nano boron carbide reinforced flexible polymer composites with improved shielding properties

Aims: The main objective of the current research is to develop light-weight and flexible electromagnetic shielding materials with improved properties using nano/mikro boron carbide dispersed into polymer based matrices after surface modification. Methods: Nano/micro boron carbide particles with various morphologies were synthesized by sol-gel techniques and the obtained particles were surface modified with different functional groups. After mixing the particles with different polymers using high shear mixer, shielding composite plates were shaped using injection moulding and warm pressing. Results: It was shown that sol-gel technique was able to produce boron carbide particles with controlled morphology and better shielding properties could be obtained using these particles within polymeric matrices leading to the formation of flexible composites. Conclusions: Overall, it was found that light-weight and effective shielding materials could be obtained using boron carbide particles dispersed within polymeric matrices. Surface modification of the particles is critical for good dispersion and hence to get better final properties. The concentration of the reinforcing particles also affects the properties in terms of energy absorption and shielding

Processing and properties of new generation radiation shielding nano composites

Electromagnetic radiation from equipments in medical diagnostic centers or nuclear reactors causes ionization including gamma rays and x-rays that are well known to be very harmful to human health. Therefore, flexible, light-weighed and environmentally friendly shielding materials that can replace toxic and very heavy Pb based materials are required. In the present work, synthesized and surface modified micro/nano B4C particles are distributed within polymeric matrices in order to obtain flexible shielding materials. The effect of surface functionalization and concentration of boron carbide on the distribution characteristics of boron carbide and the final properties of the composites are examined