Alice S. Cary to Mr. Meredith (Undated)

https://egrove.olemiss.edu/mercorr_pro/1671/thumbnail.jp

Embodiment and social distancing: Practices

A collection of five video essays on embodiment and social distancing, with a focus on practices. RAFFAELE RUFO, “Dancing Together Alone: What Can Be Learnt About Connection When Touch is Forbidden?” (00:10): This video essay reengages the experience of leading a dance improvisation practice on Zoom during the Coronavirus lockdown. As a tango and contact improvisation dancer confined at home, I felt urged to ask: what can be learnt about embodied connection when we are not allowed to physically touch each other? ANAT BEN-DAVID AND CATHARINE ANNE CARY, “What’s the Matter?” (05:54): Performers, scenographers, musicians and wordsmiths Anat Ben-David and Catharine Cary improvised via ZOOM every Tuesday from March to May 2020. Embracing latency, zoom’s affordances, limitations and distortions, they show here excerpts of a transformed body of work. Separated by 5218 km, given the Covid-19 situation, it could have been 200 meters. DEANNA BORLAND-SENTINELLA, LOUISE GWENNETH PHILLIPS, AND ALICE OWEN, “Virtually Embodied: Remembering the Sensations of Connection” (12:04): This film is an exploration of the body: Being present to place and time; being aware of connection with others, whether that be in reality or through virtual connection and sensorial memory. NATHALIE S. FARI, “Notes from a zoom 5Rhythms® session” (17:10): By using a three-hour 5Rhythms® online workshop as basis, this video sheds light into the ways in which the practitioner interacts and engages with both one’s own bodily awareness and the new technology of zoom. AMBERBECKYCREATIVE, “Sheltering in Spacetimematterings: Audiovisual Considerations of Social Distancing” (22:42): Two socially distant authors glitch audiovisual intra-actions through embodied (dis)orientations of space, time, and matter in past/present/future collapsed to (re)present what it’s like to shelter in place during the COVID-19 pandemic

Geographical guide to floras of the world : an annotated list with special reference to useful plants and common plant names : Part 1. Africa, Australia, North America, South America, and islands of Atlantic, Pacific, and Indian oceans / by S.F. Blake and Alice C. Atwood.

no.40

A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate

<div><p>Sunitinib is a tyrosine kinase inhibitor approved for the treatment of multiple solid tumors. However, cardiotoxicity is of increasing concern, with a need to develop rational mechanism driven approaches for the early detection of cardiac dysfunction. We sought to interrogate changes in cardiac energy substrate usage during sunitinib treatment, hypothesising that these changes could represent a strategy for the early detection of cardiotoxicity. Balb/CJ mice or Sprague-Dawley rats were treated orally for 4 weeks with 40 or 20 mg/kg/day sunitinib. Cardiac positron emission tomography (PET) was implemented to investigate alterations in myocardial glucose and oxidative metabolism. Following treatment, blood pressure increased, and left ventricular ejection fraction decreased. Cardiac [¹⁸F]-fluorodeoxyglucose (FDG)-PET revealed increased glucose uptake after 48 hours. [¹¹C]Acetate-PET showed decreased myocardial perfusion following treatment. Electron microscopy revealed significant lipid accumulation in the myocardium. Proteomic analyses indicated that oxidative metabolism, fatty acid β-oxidation and mitochondrial dysfunction were among the top myocardial signalling pathways perturbed. Sunitinib treatment results in an increased reliance on glycolysis, increased myocardial lipid deposition and perturbed mitochondrial function, indicative of a fundamental energy crisis resulting in compromised myocardial energy metabolism and function. Our findings suggest that a cardiac PET strategy may represent a rational approach to non-invasively monitor metabolic pathway remodeling following sunitinib treatment.</p></div