6 research outputs found
Oil, Gas and Minerals: The Impact of Resource-Dependence and Governance on Sustainable Development
It has often been argued that oil, gas and minerals may have a negative impact on development as measured by
income per capita. This does not say much about sustainability, which is critical for developing countries whose
economic growth derives primarily from the exploitation of exhaustible resources
Resource Dependence and Armed Violence: Impact on Sustainability in Developing Countries
Development Studies in Tanzania : Historical Trajectory and Future Visions
The chapter discusses the history, dilemmas and future visions of Development Studies in Tanzania, especially from the perspective of Institute of Development Studies in the University of Dar es Salaam. It shows how in the 1970s Development Studies played a significant role in the consolidation of state ideology of African socialism among university students, and since then, has gradually evolved into a recognized discipline with MA and PhD programmes. Over the years, the discipline has dealt with dilemmas related to its multidisciplinary nature, state ideologies, international donor agendas and the changing demands concerning academic publications. Recently, Development Studies in Tanzania has started to address these dilemmas and search for a new identity, for example, through establishing a Tanzanian Development Studies Association.peerReviewe
Neurocognitive Outcome of Children Exposed to Perinatal Mother-to-Child Chikungunya Virus Infection: The CHIMERE Cohort Study on Reunion Island
International audienceBackgroundLittle is known about the neurocognitive outcome in children exposed to perinatal mother-to-child Chikungunya virus (p-CHIKV) infection.MethodsThe CHIMERE ambispective cohort study compared the neurocognitive function of 33 p-CHIKV-infected children (all but one enrolled retrospectively) at around two years of age with 135 uninfected peers (all enrolled prospectively). Psychomotor development was assessed using the revised Brunet-Lezine scale, examiners blinded to infectious status. Development quotients (DQ) with subscores covering movement/posture, coordination, language, sociability skills were calculated. Predictors of global neurodevelopmental delay (GND, DQâ€85), were investigated using multivariate Poisson regression modeling. Neuroradiologic follow-up using magnetic resonance imaging (MRI) scans was proposed for most of the children with severe forms.ResultsThe mean DQ score was 86.3 (95%CI: 81.0â91.5) in infected children compared to 100.2 (95%CI: 98.0â102.5) in uninfected peers (P<0.001). Fifty-one percent (nâ=â17) of infected children had a GND compared to 15% (nâ=â21) of uninfected children (P<0.001). Specific neurocognitive delays in p-CHIKV-infected children were as follows: coordination and language (57%), sociability (36%), movement/posture (27%). After adjustment for maternal social situation, small for gestational age, and head circumference, p-CHIKV infection was found associated with GND (incidence rate ratio: 2.79, 95%CI: 1.45â5.34). Further adjustments on gestational age or breastfeeding did not change the independent effect of CHIKV infection on neurocognitive outcome. The mean DQ of p-CHIKV-infected children was lower in severe encephalopathic children than in non-severe children (77.6 versus 91.2, P<0.001). Of the 12 cases of CHIKV neonatal encephalopathy, five developed a microcephaly (head circumference <â2 standard deviations) and four matched the definition of cerebral palsy. MRI scans showed severe restrictions of white matter areas, predominant in the frontal lobes in these children.ConclusionsThe neurocognitive outcome of children exposed to perinatal mother-to-child CHIKV infection is poor. Severe CHIKV neonatal encephalopathy is associated with an even poorer outcome