Characterization of the Hamamatsu R11265-103-M64 multi-anode photomultiplier tube

The aim of this paper is to fully characterize the new multi-anode photomultiplier tube R11265-103-M64, produced by Hamamatsu. Its high effective active area (77%), its pixel size, the low dark signal rate and the capability to detect single photon signals make this tube suitable for an application in high energy physics, such as for RICH detectors. Four tubes and two different bias voltage dividers have been tested. The results of a standard characterization of the gain and the anode uniformity, the dark signal rate, the cross-talk and the device behaviour as a function of temperature have been studied. The behaviour of the tube is studied in a longitudinal magnetic field up to 100 Gauss. Shields made of a high permeability material are also investigated. The deterioration of the device performance due to long time operation at intense light exposure is studied. A quantitative analysis of the variation of the gain and the dark signals rate due to the aging is described.Comment: 22 page

Higgs boson properties and decays, searches for high mass Higgs bosons, and Higgs boson pair production

The study of the scalar sector of the standard model of particle physics is one of the main goals of the LHC physics programme. A precise characterisation of the Higgs boson, searches for extensions of the scalar sector, and the study of Higgs boson pair production are complementary in this exploration. This paper describes the status of Higgs boson physics analyses performed by the ATLAS and CMS Collaborations, focusing on the latest results from pp collisions at √s = 13 TeV recorded in 2016, for an integrated luminosity of about 36fb−1

Reflecting a… “Bit”. What relationship between metacognition and ICT?

Abstract Using Information and Communication Technologies (ICT) in educational environments has become widespread in latest years. Since research underlined the important role played by metacognition and self-regulation abilities in fostering learning outcomes, the relationship between these aspects appears to be particularly worthy of investigation. In this review, we present 14 studies that have deepened the relationship between ICT, metacognitive skills and learning outcomes by identifying two main categories. Some articles investigated the effects of ICT environments combined with metacognitive aspects of learning outcomes, while others investigated the reciprocal relationship between ICT and metacognition. In general, from our review, the interaction between ICT and metacognition in producing better learning outcomes appears well established and the results highlight a bi-directional relationship between metacognition and ICT, but also allow to draw attention to gaps requiring further research

Sport identification, moral perceptions and collective action: A study with young football players

We conducted a cross-sectional study investigating whether sport identification predicts different forms of collective action intentions aimed to redress the unfavourable condition faced by disadvantaged individuals. In doing so, moral perceptions (moral convictions, moral violation and moral obligation) were tested as mediators. Participants were young football players from the grassroots of a professional Italian club (N = 111). Results revealed that sport identification was indirectly associated with greater willingness to engage in both normative and non-normative solidarity-based collective action via stronger moral obligation perceptions; moral convictions mediated the relationship between sport identification and normative collective action, while no mediation effects emerged for moral violation. We discuss findings in relation to collective action and sport research

Preliminary non-invasive study of Roman glasses from Jesolo (Venice), Italy

Archaeological excavations at ‘Le Mure’ site (Jesolo, VE, Italy) have followed each other since the sixties, when the first evidence of an Early Medieval church (6th–7th century AD) was found under the ruins of a Medieval Cathedral (11th–12th AD). The last few years of investigations by Ca’Foscari University have led to the collection of large amounts of glass fragments, including many tesserae, dating between the 4th and the 12th centuries AD. A selection of glass fragments and mosaic tesserae taken from the excavations performed in 2013–14 at this site were studied by means of reflectance spectroscopy in order to identify their chromophore ions, in particular Cu0, Cu2+, Co2+, Fe2+ and Fe3+, which were detected in both transparent and opaque samples. In addition, the use of high resolution close-up images allowed for the attribution of surface characteristics to specific manufacturing techniques, while glass chemistry was studied in order to group them into known compositional classes. This study, carried out by non-invasive analytical techniques that allowed for the acquisition of preliminary data, will prove useful in driving further methodologies involving other non-invasive and micro-invasive analysis in order to obtain archaeometric information that can be related to concurrent archaeological results

FIGHTING FOR POWER IN GAME OF THRONES: SOCIAL DOMINANCE ORIENTATION, CHARACTER MORALITY, AND COLLECTIVE VERSUS INDIVIDUAL INTERESTS WORLDVIEWS

Focusing on the "Game of Thrones" saga, we investigated among fans ( N = 338) whether social dominance orientation (SDO) is associated with morality attributed to characters of TV fictions and, in turn, individuals' worldviews. We further considered the distinction in SDO-Dominance (SDO-D) and SDO-Antiegaliatarianism (SDO-A). Results revealed that SDO-D was positively associated with morality attributed to characters using harsh power-achievement strategies; SDO-A was negatively associated with morality attributed to characters fighting for collective interests and supporting equality principles. Morality attributed to some characters mediated the associations of the two SDO dimensions with participants' worldview about pursuing collective rather than individual interests

Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids

Aggressive hepatocellular carcinoma (HCC) overexpressing Angiopoietin-2 (ANG-2) (a protein linked with angiogenesis, proliferation, and epithelial–mesenchymal transition (EMT)), shares 95% of up-regulated genes and a similar poor prognosis with the proliferative subgroup of intrahepatic cholangiocarcinoma (iCCA). We analyzed the pro-invasive effect of ANG-2 and its regulator vascular endothelial growth factor (VEGF) on HCC and CCA spheroids to uncover posUsible common ways of response. Four cell lines were used: Hep3B and HepG2 (HCC), HuCC-T1 (iCCA), and EGI-1 (extrahepatic CCA). We treated the spheroids with recombinant human (rh) ANG-2 and/or VEGF and then observed the changes at the baseline, after 24 h, and again after 48 h. Proangiogenic stimuli increased migration and invasion capability in HCC- and iCCA-derived spheroids and were associated with a modification in EMT phenotypic markers (a decrease in E-cadherin and an increase in N-cadherin and Vimentin), especially at the migration front. Inhibitors targeting ANG-2 (Trebananib) and the VEGF (Bevacizumab) effectively blocked the migration ability of spheroids that had been stimulated with rh-ANG-2 and rh-VEGF. Overall, our findings highlight the critical role played by ANG-2 and the VEGF in enhancing the ability of HCC- and iCCA-derived spheroids to migrate and invade, which are key processes in cancer progression

Run 2 Upgrades to the CMS Level-1 Calorimeter Trigger

The CMS Level-1 calorimeter trigger is being upgraded in two stages to maintain performance as the LHC increases pile-up and instantaneous luminosity in its second run. In the first stage, improved algorithms including event-by-event pile-up corrections are used. New algorithms for heavy ion running have also been developed. In the second stage, higher granularity inputs and a time-multiplexed approach allow for improved position and energy resolution. Data processing in both stages of the upgrade is performed with new, Xilinx Virtex-7 based AMC cards.Comment: 10 pages, 7 figure

Care When It Counts: Establishing Trauma-Sensitive Care as a Preventative Approach for 0–3-Year-Old Children Suffering from Trauma and Chronic Stress

Adverse childhood experiences are an important societal concern. Children aged 0-3 are particularly vulnerable to unpredictable chronic stress due to the critical period for brain development and attachment. Trauma-sensitive care is a preventative approach to reduce the burden of stressful experiences by committing to positive relationships. Professional caregivers are ideally placed to offer trauma-sensitive care; however, earlier research reveals that the tools they need to consciously apply trauma-sensitive care principles are missing. The current study organized living labs (co-creative research method) to present trauma-sensitive care as a preventative approach aimed at children aged 0-3. Two living labs were organized in Belgium and Hungary, where professional caregivers collaborated to create a protocol that offers guidelines on how to implement trauma-sensitive care. The resulting protocol included a theoretical foundation on trauma as well as a translation of these guidelines into practical recommendations. The protocol was evaluated by incorporating it into a training intervention delivered to 100 professional caregivers from childcare organizations across four European countries. The protocol received positive feedback from participants, with results indicating a self-reported increase in knowledge, attitude and practice of trauma-sensitive care principles. We conclude that this trauma-sensitive care protocol is a promising answer to the needs of professional caregivers working with children aged 0-3