Prevalence of Cell Phone Sharing

With the growing mobile-only population landline telephone surveys are increasingly complemented by mobile phone interviews using a dual frame approach. Typically it is assumed that a mobile phone is a personal device solely used by one individual. Even though several articles dealt with the eventuality that several persons may be reached when calling a mobile phone number, respondent selection procedures are currently not implemented. This paper provides further insight into this phenomenon. Using data from a 2010/11 survey conducted in the German cell phone population mobile phone sharing was examined indicating noteworthy prevalence rates. The sharing population also differed to the non-sharing population with respect to sociodemographic variables. Results are discussed in light of potential consequences for field work

Note on maximal split-stable subgraphs

A multigraph G=(V,R∪B) with red and blue edges is an R/B-split graph if V is the union of a red and a blue stable set. Gavril has shown that R/B-split graphs yield a common generalization of split graphs and König–Egerváry graphs. Moreover, R/B-split graphs can be recognized in linear time. In this note, we address the corresponding optimization problem: identify a set of vertices of maximal cardinality that decomposes into a red and a blue stable set. This problem is NP-hard in general. We investigate the complexity of special and related cases (e.g., (anti-)chains in partial orders and stable matroid bases) and exhibit some NP-hard cases as well as polynomial ones

Freezing point osmometry of milk to determine the additional water content – an issue in general quality control and German food regulation

<p>Abstract</p> <p>Background</p> <p>The determination of the osmolality of aqueous samples using a freezing point osmometer is a well-established, routine laboratory method. In addition to their use in clinical and pharmaceutical laboratories, freezing point osmometers are also employed in food testing laboratories. One application is the determination of the osmolality of milk. Although cow's milk is a natural product whose water content is approximately 87%, the osmolality of milk is a significant value when the milk is collected from a larger population of animals. This value is used in milk processing to control the water content, based on the German Food Control Regulations for Milk.</p> <p>Results</p> <p>Measurement of the freezing point and osmolality of milk samples was performed with a Knauer Semi-Micro Freezing Point Osmometer. Osmolality was measured for the untreated milk samples and following their dilution (by volume) with 10% and 50% water. The measurements were made after 1, 4 and 7 days to evaluate changes over time. All measurement values for the undiluted milk were spread over a small interval with an average of 271 mOsmol/kg. After mixing the milk samples with 10% water, the average decreased to 242 mOsmol/kg, while mixing with 50% water resulted in an average osmolality of 129 mOsmol/kg. There was no significant change for the osmolality within the 7 days (measurements from days 1, 4 and 7).</p> <p>Conclusion</p> <p>The results observed demonstrate clearly that the additional water content of milk can be determined easily using a freezing point osmometer. Milk samples that contain additional water have a significantly decreased osmolality, corresponding to an increased freezing point. The effect on osmolality of ageing the milk samples could not be determined in this study's time-dependent measurements.</p

Health technology assessment of medical devices in europe: processes, practices, and methods

Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.Objectives: To review and compare current Health Technology Assessment (HTA) activities for medical devices (MDs) across European HTA institutions. Methods: A comprehensive approach was adopted to identify institutions involved in HTA in European countries. We systematically searched institutional Web sites and other online sources by using a structured tool to extract information on the role and link to decision making, structure, scope, process, methodological approach, and available HTA reports for each included institution. Results: Information was obtained from eighty-four institutions, forty-seven of which were analyzed. Fifty-four methodological documents from twenty-three agencies in eighteen countries were identified. Only five agencies had separate documents for the assessment of MDs. A few agencies made separate provisions for the assessment of MDs in their general methods. The amount of publicly available HTA reports on MDs varied by device category and agency remit. Conclusions: Despite growing consensus on their importance and international initiatives, such as the EUnetHTA Core Model®, specific tools for the assessment of MDs are rarely developed and implemented at the national level. Separate additional signposts incorporated in existing general methods guides may be sufficient for the evaluation of MDs.EC/FP7/305983/EU/Advancing and strengthening the methodological tools and practices relating to the application and implementation of Health Technology Assessment (HTA)/ADVANCE_HT

On decorating Christmas trees

The following decision problem is regarded in this note: given a tree, decide if it is possible to cover exactly k nodes of the tree with stars (that is with trees of depth 1. We give a proof of the polynomiality of the problem which directly leads to a linear time algorithm

Etude de la survie du souchet comestible (Cyperus esculentus) et de la renouée du Japon (Reynoutria japonica) lors du compostage et de la méthanisation

Cette étude a évalué le risque que le souchet comestible et la renouée du Japon se propagent par le compost ou le digestat et colonisent ainsi de nouvelles parcelles. Pour ce faire, plusieurs essais de compostage et de méthanisation ont été réalisés, dans la pratique et en laboratoire

Studie zur Persistenz von Erdmandelgras (Cyperus esculentus) und Japanknöterich (Reynoutria japonica) in Kompostierungs- und Vergärungsprozessen

In dieser Studie wurde das Risiko, dass sich das Erdmandelgras und Japanknöterich mittels ausgebrachtem Kompost oder Gärgut ausbreiten und weitere Parzellen befallen können, evaluiert. Dazu wurden verschiedene Kompostierungs- und Vergärungsversuche unter Praxis und Laborbedingungen durchgeführt

PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS

Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we focused on phosphoinositide 3-kinase (PI3K) and its product phosphatidylinositol(3,4,5)-trisphosphate (PIP3). We demonstrate that adult PNS neurons utilise two catalytic subunits of PI3K for axon regeneration: p110α and p110δ. However in the CNS, axonal PIP3 decreases with development at the time when axon transport declines and regenerative competence is lost. Overexpressing p110α in CNS neurons had no effect, however expression of p110δ restored axonal PIP3 and increased regenerative axon transport. p110δ expression enhanced CNS regeneration in both rat and human neurons and in transgenic mice, functioning in the same way as the hyperactivating H1047R mutation of p110α. Furthermore, viral delivery of p110δ promoted robust regeneration after optic nerve injury. These findings establish a deficit of axonal PIP3 as a key reason for intrinsic regeneration failure and demonstrate that native p110δ facilitates axon regeneration by functioning in a hyperactive fashion

Airway management in neonates and infants: European Society of Anaesthesiology and Intensive Care and British Journal of Anaesthesia joint guidelines.

Airway management is required during general anaesthesia and is essential for life-threatening conditions such as cardiopulmonary resuscitation. Evidence from recent trials indicates a high incidence of critical events during airway management, especially in neonates or infants. It is important to define the optimal techniques and strategies for airway management in these groups. In this joint European Society of Anaesthesiology and Intensive Care (ESAIC) and British Journal of Anaesthesia (BJA) guideline on airway management in neonates and infants, we present aggregated and evidence-based recommendations to assist clinicians in providing safe and effective medical care. We identified seven main areas of interest for airway management: i) preoperative assessment and preparation; ii) medications; iii) techniques and algorithms; iv) identification and treatment of difficult airways; v) confirmation of tracheal intubation; vi) tracheal extubation, and vii) human factors. Based on these areas, Population, Intervention, Comparison, Outcomes (PICO) questions were derived that guided a structured literature search. GRADE (Grading of Recommendations, Assessment, Development and Evaluation) methodology was used to formulate the recommendations based on those studies included with consideration of their methodological quality (strong '1' or weak '2' recommendation with high 'A', medium 'B' or low 'C' quality of evidence). In summary, we recommend: 1. Use medical history and physical examination to predict difficult airway management (1С). 2. Ensure adequate level of sedation or general anaesthesia during airway management (1B). 3. Administer neuromuscular blocker before tracheal intubation when spontaneous breathing is not necessary (1С). 4. Use a videolaryngoscope with an age-adapted standard blade as first choice for tracheal intubation (1B). 5. Apply apnoeic oxygenation during tracheal intubation in neonates (1B). 6. Consider a supraglottic airway for rescue oxygenation and ventilation when tracheal intubation fails (1B). 7. Limit the number of tracheal intubation attempts (1C). 8. Use a stylet to reinforce and preshape tracheal tubes when hyperangulated videolaryngoscope blades are used and when the larynx is anatomically anterior (1C). 9. Verify intubation is successful with clinical assessment and end-tidal CO2 waveform (1C). 10. Apply high-flow nasal oxygenation, continuous positive airway pressure or nasal intermittent positive pressure ventilation for postextubation respiratory support, when appropriate (1B)