Programas de controle das mastites causadas por microrganismos contagiosos e do ambiente

Este trabalho foi elaborado com o objetivo de apresentar os conceitos em que se baseiam os programas de controle da mastite, em uso na maioria das indústrias leiteiras desenvolvidas. Foram abordados os fundamentos dos programas de controle, as características dos patógenos mais comuns, os fatores relacionados à ocorrência da doença e a síntese do programa de controle. Destina-se prioritariamente a médicos veterinários e estudantes, embora outros profissionais e produtores interessados no tema possam também usá-lo.bitstream/item/81916/1/Programas-de-controle-das-mastites.pd

On the effective action of the vacuum photon splitting in Lorentz-violating QED

We consider one-loop radiative corrections from Lorentz- and CPT- violating extended QED to address the specific problem of finding explicitly an effective action describing amplitude of photon triple splitting. We show that it is not possible to find a nonzero photon triple splitting effective action, at least by using the derivative expansion method (at zero external momenta), up to leading order in the Lorentz- and CPT- violating parameter.Comment: 4 pages, version to appear in EP

Rinite atrófica dos suínos: alternativas de controle.

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Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: Implication for neuroprotective therapies

Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain suggesting that besides a decrease on BDNF levels a reduction of TrkB expression could also contribute to diminished neurotrophic support in HD. BDNF can also bind to p75 neurotrophin receptor (p75(NTR)) modulating TrkB signaling. Therefore, in this study we have analyzed the levels of p75(NTR) in several HD models, as well as in HD human brain. Our data demonstrates a p75(NTR)/TrkB imbalance in the striatum of two different HD mouse models, Hdh(Q111/111) homozygous knockin mice and R6/1 mice that was also manifested in the putamen of HD patients. The imbalance between TrkB and p75(NTR) levels in a HD cellular model did not affect BDNF-mediated TrkB activation of prosurvival pathways but induced activation of apoptotic cascades as demonstrated by increased JNK phosphorylation. Moreover, BDNF failed to protect mutant huntingtin striatal cells transfected with p75(NTR) against NMDA-mediated excitotoxicity, which was associated with decreased Akt phosphorylation. Interestingly, lack of Akt activation following BDNF and NMDA treatment correlated with increased PP1 levels. Accordingly, pharmacological inhibition of PP1 by okadaic acid (OA) prevented mutant huntingtin striatal cell death induced by NMDA and BDNF. Altogether, our findings demonstrate that the p75(NTR)/TrkB imbalance induced by mutant huntingtin in striatal cells associated with the aberrant activity of PP1 disturbs BDNF neuroprotection likely contributing to increasing striatal vulnerability in HD. On the basis of this data we hypothesize that normalization of p75(NTR) and/or TrkB expression or their signaling will improve BDNF neuroprotective therapies in HD. Cell Death and Disease (2013) 4, e595; doi:10.1038/cddis.2013.116; published online 18 April 201

Black hole formation in bidimensional dilaton gravity coupled to scalar matter systems

This work deals with the formation of black hole in bidimensional dilaton gravity coupled to scalar matter fields. We investigate two scalar matter systems, one described by a sixth power potential and the other defined with two scalar fields containing up to the fourth power in the fields. The topological solutions that appear in these cases allow the formation of black holes in the corresponding dilaton gravity models.Comment: Latex, 9 pages. Published in Mod. Phys. Lett. A14 (1999) 268

Homeopatia: uma opção de tratamento da mamite bovina

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Formulação de um índice (IRA) para aplicação na caracterização e classificação de rebanhos com rinite atrófica.

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