380 research outputs found

    Observations of current rings in the Antarctic Zone at Drake Passage

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    Time series of current velocity and temperature from several depths at a site near the center of Drake Passage show features that can plausibly be interpreted as current rings. Between June 1975 and January 1976, five cyclonic rings from the Continental Water Boundary and one anticyclonic ring from the Polar Front passed over the site. The diameters of the rings varied from 30 km to 130 km, and all of them extended vertically to a depth of at least 2500 m. The rings exhibited maximum spin velocities of about 20 cm sec−1 at 1000 m depth and 10 cm sec−1 at 2500 m. Their translatory motion, which was toward the north at about 4 cm sec−1, contained a westward component relative to the ambient flow. The magnitude of the westward component suggests that it may have resulted from an interaction between rings and the sea floor, which slopes downward to the northeast at the mooring site. The total available mechanical energy of the rings (kinetic plus potential) varied from 6.2 × 1013 j in the smallest ring to 9.9 × 1014 in the largest. The available heat, relative to the Antarctic Zone, was several orders of magnitude larger: −3.0 × 1017 j for the smallest ring and −3.6 × 1018 j for the largest. The numbers indicate that current rings may play an important role in dissipating the kinetic energy of the circumpolar fronts and that they may be responsible for a significant poleward flux of heat in the Southern Ocean

    On the Choquet multiple criteria preference aggregation model: theoretical and practical insights from a real-world application

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    We consider the use of the Choquet integral for evaluating projects or actions in a real-world application starting from the case of the re-qualification of an abandoned quarry. Despite the Choquet integral being a very well-known preference model for which there is a rich and well developed theory, its application in a multiple criteria decision aiding perspective requires some specific methodological developments. This led us to work out and implement, in practice, two new procedures: A first procedure to build interval scales with the objective of assigning utility values on a common scale to the criteria performances, and a second one to construct a ratio scale for assigning numerical values to the capacities of the Choquet integral. This article discusses the strengths and weaknesses of the Choquet integral as appearing in the case study, proposing as well insights related to the interaction of the experts within a focus grou

    HCV reinfection incidence and spontaneous clearance rates in HIV-positive men who have sex with men in Western Europe

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    BACKGROUND & AIMS: Moderate cure rates of acute hepatitis C virus (HCV) infections with pegylated interferon and ribavirin have been described in the last decade in men who have sex with men (MSM), who are also coinfected with the human immunodeficiency virus (HIV). However, a subsequent high incidence of HCV reinfections has been reported regionally in men who both clear the infection spontaneously or who respond to treatment. METHODS: Retrospective analysis of reinfections in HIV infected MSM in eight centers from Austria, France, Germany, and the UK within the NEAT network between May 2002 and June 2014. RESULTS: Of 606 individuals who cleared HCV spontaneously or were successfully treated, 149 (24.6%) presented with a subsequent HCV reinfection. Thirty out of 70 (43%) who cleared again or were successfully treated, presented with a second reinfection, 5 with a third, and one with a fourth reinfection. The reinfection incidence was 7.3/100 person-years (95% CI 6.2-8.6). We found a trend for lower incidence among individuals who had spontaneously cleared their incident infection than among individuals who were treated (Hazard ratio 0.62, 95% CI 0.38-1.02, p=0.06). Spontaneous clearance of reinfection was associated with ALT levels >1000IU/ml and spontaneous clearance of a prior infection. CONCLUSIONS: HCV reinfection is an issue of major concern in HIV-positive MSM. Prevention strategies are needed for high risk groups to reduce morbidity and treatment costs. HIV-positive MSM with a prior HCV infection should be tested every 3 to 6months for reinfection. Those who had achieved a reinfection should be tested every 3months. LAY SUMMARY: We evaluated the occurrence of HCV reinfection in HIV-positive men who have sex with men. We found an alarming incidence of 7.3/100 person-years. Prevention measures need to address this specific subgroup of patients at high risk for HCV
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