112 research outputs found
A microwave promoted and Lewis acid catalysed solventless approach to 4-azasteroids
The preparation of 3-oxo-4-azasteroid fromA-nor-3,5-secosteroid-3-oic acid is described in a
solventless condition catalysed by Lewis acid under microwave irradiation.We utilized urea
as an environmentally benign source for the generation of ammonia for the aza cyclization
reaction
A mechanistic study of 2- vinylbenzimidazole formation from 2-(2'-haloethyl) benzimidazoles. Synthesis of highly electron rich vinylic compounds by general base and specific acid - general base
A comparison of the cytotoxic and physical properties of aziridinyl quinone derivatives based on pyrrolo[1,2-a] benzimidazole and pyrrolo[1,2-a]indole ring systems
Determination of pKa values for the mitomycin C redox couple by titration, pH rate profiles, and nernst-Clark Fits. studies of methanol elimination, carbocation formation, and carbocation/quinone method equilibrium
Indium(III) trifluoromethanesulfonate: An efficient reusable catalyst for the alkynylation-cyclization of 2-aminoaryl ketones and synthesis of 2,4-disubstituted quinolines
An environmentally friendly and highly efficient procedure
for the preparation of 2,4-disubstituted quinoline derivatives
has been developed by a simple alkynylation 13cyclization reaction
of 2-aminoaryl ketones with phenylacetylenes in the presence of indium(
III) trifluoromethanesulfonate In(OTf)3 under microwave irradiation
and solvent-free conditions. This catalyst can be recovered
after the reaction and reused efficiently in subsequent runs
Microwave-promoted one-pot synthesis of 4H-thiopyrans from a,b-unsaturated ketones via a three-component reaction
āAn eļ¬cient one-pot synthesis of substituted 4H-thiopyrans has been accomplished from a three-component reaction of
a,b-unsaturated ketones, Lawessonās reagent and alkynes under microwave irradiation
Baker's Yeast-catalysed ring opening of benzofuroxans : an efficient green synthesis of aryl-1,2-diamines
A simple and inexpensive method for the reductive cleavage of NāO
bond of benzofuroxans with bakersā yeast under nonfermenting condition in
aqueous media was achieved. The procedure gives excellent yields of aryl-1,
2-diamines
Microwave promoted one-pot synthesis of novel A-ring fused steroidal dehydropiperazines
The preparation of ring-A fused steroidal dehydropiperazine at the 3,4-position is herein
described. The novel steroidal dehydropiperazines were prepared from the annulation reaction
of ethylenediamine with 3-keto-4-en steroids in a one-pot reaction under microwave
irradiation. The key step involves base catalysed aerial oxidation of the C-6 methylene group
followed by cyclocondensation of ethylenediamine via Michael addition reaction
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