Work and non-work-related antecedents of expatriates' well-being : A meta-analysis

Studies show a reduction in expatriates' well-being while abroad which entails a risk of low performance or even termination of the assignment abroad. To extend the knowledge of antecedents of expatriates' well-being, this meta-analytic review combines the empirical results from 24 studies. Concerning the conservation of resources theory, we distinguish between work-related and non-work-related antecedents (resources) and expose their relationship with expatriates' work well-being and general well-being. The meta-analysis shows that work well-being is positively anteceded by organizational support, work adjustment, and spousal support, whereas job factors and work-family interference are associated with decreased work well-being. General well-being negatively relates to work-family interference factors. The antecedents with the highest relative effect size are job factors on the negative side (resource loss) and organizational support on the positive side (resource gain). Work-family interference has the broadest impact on both work well-being and general well-being.© 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).The author gratefully acknowledges funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Actions grant agreement No. 765355 (GLOMO, “Global Mobility of Employees”, https://glomo.eu/ ).fi=vertaisarvioitu|en=peerReviewed

Optimal boundary control for the Cahn-Hilliard-Navier-Stokes Equations

In this work, we study an optimal boundary control problem for a Cahn - Hilliard -Navier-Stokes (CHNS) system in a two dimensional bounded domain. The CHNS system consists of a Navier-Stokes equation governing the fluid velocity field coupled with a convective Cahn - Hilliard equation for the relative concentration of the fluids. An optimal control problem is formulated as the minimization of a cost functional subject to the controlled CHNS system where the control acts on the boundary of the Navier-Stokes equations. We first prove that there exists an optimal boundary control. Then we establish that the control-to-state operator is Frechet differentiable and derive first-order necessary optimality conditions in terms of a variational inequality involving the adjoint system

Activated Protein Kinase C (PKC) Is Persistently Trafficked with Epidermal Growth Factor (EGF) Receptor

Protein kinase Cs (PKCs) are activated by lipids in the plasma membrane and bind to a scaffold assembled on the epidermal growth factor (EGF) receptor (EGFR). Understanding how this complex is routed is important, because this determines whether EGFR is degraded, terminating signaling. Here, cells were preincubated in EGF-tagged gold nanoparticles, then allowed to internalize them in the presence or absence of a phorbol ester PKC activator. PKC colocalized with EGF-tagged nanoparticles within 5 min and migrated with EGFR-bearing vesicles into the cell. Two conformations of PKC-epsilon were distinguished by different primary antibodies. One, thought to be enzymatically active, was on endosomes and displayed a binding site for antibody RR (R&D). The other, recognized by Genetex green (GG), was soluble, on actin-rich structures, and loosely bound to vesicles. During a 15-min chase, EGF-tagged nanoparticles entered large, perinuclear structures. In phorbol ester-treated cells, vesicles bearing EGF-tagged nanoparticles tended to enter this endocytic recycling compartment (ERC) without the GG form. The correlation coefficient between the GG (inactive) and RR conformations on vesicles was also lower. Thus, active PKC has a Charon-like function, ferrying vesicles to the ERC, and inactivation counteracts this function. The advantage conferred on cells by aggregating vesicles in the ERC is unclear

The future of global mobility

This article presents different kinds of international work featured in the literature, and a number of new strategic trends following the COVID-19 pandemic, identified in recent interviews with the heads of global mobility units in 22 European companies. Given our findings, which describe the extensive impacts of the crisis on global mobility, we make two main recommendations for MNCs: (1) they need to reconsider global mobility policies in a new situation after the COVID pandemic; and (2) invest in overcoming operational and legal challenges, to reduce uncertainties among globally mobile employees surrounding the use of flexible and remote working arrangements