27 research outputs found

    Recentes avanços na neuroquímica da consolidação da memória e evocação: impacto na concepção atual dos distúrbios de memória

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    Submitted by Ilno Conceição ([email protected]) on 2012-11-22T00:56:51Z No. of bitstreams: 1 Recent advances in the neurochemistry of memory consolidation and retrieval impact on current views on memory disorders.pdf: 117846 bytes, checksum: 6b15d9c0405b1fb7bcab75e5b1b22734 (MD5)Approved for entry into archive by Michele Fernanda([email protected]) on 2012-11-25T00:56:32Z (GMT) No. of bitstreams: 1 Recent advances in the neurochemistry of memory consolidation and retrieval impact on current views on memory disorders.pdf: 117846 bytes, checksum: 6b15d9c0405b1fb7bcab75e5b1b22734 (MD5)Made available in DSpace on 2012-11-25T00:56:32Z (GMT). No. of bitstreams: 1 Recent advances in the neurochemistry of memory consolidation and retrieval impact on current views on memory disorders.pdf: 117846 bytes, checksum: 6b15d9c0405b1fb7bcab75e5b1b22734 (MD5) Previous issue date: 2005Many aspects of the molecular basis of declarative memory formation, retrieval and extinction have been established in the past few years. These aspects add to, and partly modify, some long-standing concepts on memory disorders. This article will review data from our laboratories and comment on their impact on these concepts. Particular emphasis will be placed on: a) new findings on the modulation of working memory; b) the separation of short- from long-term memory; c) the molecular pharmacology of memory retrieval.Nos últimos anos houve avanços substanciais no conhecimento dos mecanismos moleculares da aquisição, consolidação e evocação das memórias. Muitos desses avanços tem conseqüências importantes na compreensão e no tratamento dos diversos síndromes de déficit de memória (o déficit cognitivo que acontece com a idade avançada, as doenças degenerativas como o síndrome de Alzheimer, etc.). Discutiremos neste artigo os principais avanços na diagnóstico e terapêutica surgidos destes novos conhecimentos sobre a biologia dos processos mnemônicos
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