27 research outputs found
Perspectives sur le statut des équipements électroniques à Montréal = Perspectives on the Status of Electronic Equipment in Montreal
"The [...] anthology responds to the ever-increasing amount of electronic equipment that is perceived as obsolete, valueless or disposable. Contributors from diverse disciplines including ecology, waste management, technology activism and contemporary art bring their expertise to bear on the consumption, use, obsolescence, disposal and repair and re-use of electronic equipment.
Perspectives’ hybrid approach to these topics will be of interest to both general and specialized readers negotiating the cultural, environmental and social impacts of contemporary technology.
Essays, projects and resource materials highlight approaches and practices that question consumption patterns and propose alternative approaches to using technology. Case studies and local contexts from Montreal Quebec are related to issues and initiatives across industrialized societies." -- Publisher's website
Owl Eyes: Spotting UI Display Issues via Visual Understanding
Graphical User Interface (GUI) provides a visual bridge between a software
application and end users, through which they can interact with each other.
With the development of technology and aesthetics, the visual effects of the
GUI are more and more attracting. However, such GUI complexity posts a great
challenge to the GUI implementation. According to our pilot study of
crowdtesting bug reports, display issues such as text overlap, blurred screen,
missing image always occur during GUI rendering on different devices due to the
software or hardware compatibility. They negatively influence the app
usability, resulting in poor user experience. To detect these issues, we
propose a novel approach, OwlEye, based on deep learning for modelling visual
information of the GUI screenshot. Therefore, OwlEye can detect GUIs with
display issues and also locate the detailed region of the issue in the given
GUI for guiding developers to fix the bug. We manually construct a large-scale
labelled dataset with 4,470 GUI screenshots with UI display issues and develop
a heuristics-based data augmentation method for boosting the performance of our
OwlEye. The evaluation demonstrates that our OwlEye can achieve 85% precision
and 84% recall in detecting UI display issues, and 90% accuracy in localizing
these issues. We also evaluate OwlEye with popular Android apps on Google Play
and F-droid, and successfully uncover 57 previously-undetected UI display
issues with 26 of them being confirmed or fixed so far.Comment: Accepted to 35th IEEE/ACM International Conference on Automated
Software Engineering (ASE 20
ATM/ATR kinases link the synaptonemal complex and DNA double-strand break repair pathway choice
DNA double-strand breaks (DSBs) are deleterious lesions, which must be repaired precisely to maintain genomic stability. During meiosis, programmed DSBs are repaired via homologous recombination (HR) while repair using the nonhomologous end joining (NHEJ) pathway is inhibited, thereby ensuring crossover formation and accurate chromosome segregation.1,2 How DSB repair pathway choice is implemented during meiosis is unknown. In C. elegans, meiotic DSB repair takes place in the context of the fully formed, highly dynamic zipper-like structure present between homologous chromosomes called the synaptonemal complex (SC).3,4,5,6,7,8,9 The SC consists of a pair of lateral elements bridged by a central region composed of the SYP proteins in C. elegans. How the structural components of the SC are regulated to maintain the architectural integrity of the assembled SC around DSB repair sites remained unclear. Here, we show that SYP-4, a central region component of the SC, is phosphorylated at Serine 447 in a manner dependent on DSBs and the ATM/ATR DNA damage response kinases. We show that this SYP-4 phosphorylation is critical for preserving the SC structure following exogenous (Îł-IR-induced) DSB formation and for promoting normal DSB repair progression and crossover patterning following SPO-11-dependent and exogenous DSBs. We propose a model in which ATM/ATR-dependent phosphorylation of SYP-4 at the S447 site plays important roles both in maintaining the architectural integrity of the SC following DSB formation and in warding off repair via the NHEJ repair pathway, thereby preventing aneuploidy.This work was supported by CIHR grant 119468 to M.Z., a MRC core-funded grant to E.M.-P., and National Institutes of Health grant R01GM072551 to M.P.C.Peer reviewe
Building Data Mining Applications for CRM
New Yorkxxvii, 510 p.; bibl., illus., ind.; 27c