36 research outputs found

    Post-Quantum Secure Identity-Based Encryption Scheme Using Random Integer Lattices for IoT-Enabled AI Applications

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    Identity-based encryption is an important cryptographic system that is employed to ensure confidentiality of a message in communication. This article presents a provably secure identity based encryption based on post quantum security assumption. The security of the proposed encryption is based on the hard problem, namely Learning with Errors on integer lattices. This construction is anonymous and produces pseudo random ciphers. Both public-key size and ciphertext-size have been reduced in the proposed encryption as compared to those for other relevant schemes without compromising the security. Next, we incorporate the constructed identity based encryption (IBE) for Internet of Things (IoT) applications, where the IoT smart devices send securely the sensing data to their nearby gateway nodes(s) with the help of IBE and the gateway node(s) secure aggregate the data from the smart devices by decrypting the messages using the proposed IBE decryption. Later, the gateway nodes will securely send the aggregated data to the cloud server(s) and the Big data analytics is performed on the authenticated data using the Artificial Intelligence (AI)/Machine Learning (ML) algorithms for accurate and better predictions

    Applications of Personalised Phage Therapy highlighting the importance of Bacteriophage Banks against Emerging Antimicrobial Resistance

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    Emerging antibiotic resistance is one of the most important microbiological issues of the 21st century. This poses a query regarding the future use of antibiotics and availability of other promising therapeutic alternatives. The awareness about antibiotic misuse has improved insufficiently and is evident by the increased incidences of multidrug resistant infections globally. Amongst different antibacterial therapeutic approaches phage therapy has created a niche of its own due to continuous use for treatment of human infections in Eastern Europe. Synergistic compounds along with phages have also been proposed as a better alternative compared to antibiotics or phage alone for treatment of chronic cases and seriously debilitating diseases. As such, why not allow custom made phage therapy for treatment of chronic infections? However, the success of phage therapy will depend upon instant availability of characterised bacteriophages from bacteriophage banks which may serve as the major catalyst in bringing Phage Therapy to main stream treatment alternatives or in combination therapy at least. In the current article we present a glimpse of comprehensive approach about utility of bacteriophage banks and further present personalised phage therapy in a synergistic role with antibiotics to overcome emerging antimicrobial resistance

    Effect of Rayleigh Thermal Number in Double Diffusive Non-Darcy Mixed Convective Flow in Vertical Pipe Filled with Porous Medium

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    AbstractIn the present manuscript effect of different Rayleigh number of non-darcy fully developed mixed convection in a vertical pipe filled with porous media is numerical investigation. The motion in the pipe caused by external pressure gradient and byoucey force. Non-Darcy Brinkmen-Forchheimer extended model has been introduces in momentum equation. The basic state of the flow model using fundamental assumption is formed in the form of coupled differential equation which is solved using Chebyshev Spectral collocation technique. The study is best based on double diffusive mixed convection which is governed in mathematical formulation of the problem, in which the velocity profile posses point of inflection beyond the threshold value of RaT (Positive Rayilegh thermal number). In case of Negative Rayliegh thermal number, the velocity profile may contain point of inflection in the centre zone and point of separation at the vicinity of the wall. Point of separation is create a back flow near the wall

    Hydroxylation and mechanistic studies of α, β-unsaturated compounds with alkaline hexacyanoferrate (III)

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    798-801The reactions of three α, β-unsaturated compounds of the type CH2=CHX (where X = -CN, -CONH2 and -C02 -) with alkaline hexacyanoferrate (III) have been studied. The reactions take place according to the rate expression, d[Fe(CN)63-]  / dt = k [Fe(CN)63-) (CH2=CHX] (OH-). The values of k at 318K are 7.2 x 10-4,4.45 X 10-4 and 3.2 x 10-4 (dm6mol-2s-1) in the oxidations of the respective substrates. The oxidation rates follow the order: -CN> -CONH2 > -C02  The substrates are oxidized to give diols under kinetic conditions. Tentative reaction mechanism leading to the formation of oxidation products has been suggested

    Oxidative behaviours and relative reactivities of some aliphatic, heterocyclic and aromatic aldehydes towards bis(dihydrogentellurato )cuprate(III) and argentate(III) in alkaline medium

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    190-196The oxidative behaviours and relative reactivities of some aliphatic aldehydes, XCHO (where X = H - , Me - , MeCH2 -, Me2CH-), 2-furaldehyde and aromatic aldehydes, YC6H4CHO (where Y= -H, -NO2, -Cl and -OMe) towards bis(dihydrogentellurato)metallate(III) ion (where MIlI= CUllI or AgIII) in alkaline medium have been investigated. The reactions are first order each in [aldehyde] and [MIII(H2TeO6)2]5- - but the rate is independent of [OH-]. The values of kobs in the oxidation of some aliphatic aldehydes, 2-furaldehyde and benzaldehyde in aqueous medium follow the order: Me2CH - > MeCH2 - > Me - > H - > C4H3O - > C6H5, -. The electron withdrawing substituents facilitate the rate of oxidation of benzaldehyde whereas electron donating substituents have opposite effect and the values of kobs, follow the order: - NO2 > - H > - Cl > - OMe. The pseudofirst order rate constants decrease considerably in benzaldehyde-d1., than benzaldehyde under comparable condition of experiments. Irrespective of whether the substrate is aliphatic or aromatic, the oxidation reactions occur via free radical mechanism although the substituent and isotope effects in the oxidations of aromatic aldehydes indicate that C - H bond cleavage via proton transfer may also occur. The activation parameters of the reactions have been determined and the mechanism of the reactions is discussed

    Private Blockchain Envisioned Access Control System for Securing Industrial IoT-Based Pervasive Edge Computing

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    The Industrial Internet of Things (IIoT) is able to connect machines, analytics and people with IoT smart devices, gateway nodes and edge devices to create powerful intuitivenesses to drive smarter, faster and effective business agreements. IIoT having interconnected machines along with devices can monitor, gather, exchange, and analyze information. Since the communication among the entities in IIoT environment takes place insecurely (for instance, wireless communications and Internet), an intruder can easily tamper with the data. Moreover, physical theft of IoT smart devices provides an intruder to mount impersonation and other attacks. To handle such critical issues, in this work, we design a new private blockchain-envisioned access control scheme for Pervasive Edge Computing (PEC) in IIoT environment, called PBACS-PECIIoT. We consider the private blockchain consisting of the transactions and registration credentials of the entities related to IIoT, because the information is strictly confidential and private. The security of PBACS-PECIIoT is significantly improved due to usage of blockchain as immutability, transparency and decentralization along with protection of various potential attacks. A meticulous comparative analysis exhibits that PBACS-PECIIoT achieves greater security and more functionality features, and requires low costs for communication and computational as compared to other pertinent schemes

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    Not AvailableThe present immuno-diagnostic method using soluble antigens from whole cell lysate antigen for trypanosomosis have certain inherent problems like lack of standardized and reproducible antigens, as well as ethical issues due to in vivo production, that could be alleviated by in vitro production. In the present study we have identified heat shock protein 70 (HSP70) from T. evansi proteome. The nucleotide sequence of T. evansi HSP70 was 2116 bp, which encodes 690 amino acid residues. The phylogenetic analysis of T. evansi HSP70 showed that T. evansi occurred within Trypanosoma clade and is most closely related to T. brucei brucei and T. brucei gambiense, whereas T. congolense HSP70 laid in separate clade. The two partial HSP70 sequences (HSP-1 from N-terminal region and HSP-2 from C-terminal region) were expressed and evaluated as diagnostic antigens using experimentally infected equine serum samples. Both recombinant proteins detected antibody in immunoblot using serum samples from experimental infected donkeys with T. evansi. Recombinant HSP-2 showed comparable antibody response to Whole cell lysate (WCL) antigen in immunoblot and ELISA. The initial results indicated that HSP70 has potential to detect the T. evansi infection and needs further validation on large set of equine serum samples.Not Availabl
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