An experimental investigation of drop deformation and breakup in steady, two-dimensional linear flows

We consider the deformation and burst of small fluid droplets in steady linear, two-dimensional motions of a second immiscible fluid. Experiments using a computer-controlled, four-roll mill to investigate the effect of flow type are described, and the results compared with predictions of several available asymptotic deformation and burst theories, as well as numerical calculations. The comparison clarifies the range of validity of the theories, and demonstrates that they provide quite adequate predictions over a wide range of viscosity ratio, capillary number, and flow type

Katalysis: helping Andean farmers adapt to climate change

Recent studies of global climate change paint a bleak picture for the Andes. Researchers have proposed expert-led solutions, such as improved climatic modelling and forecasting, and the breeding of drought-tolerant crop varieties. In this article, the authors argue that farmers need to shape the research agenda according to local priorities, and that smallholders and researchers should learn together. The Katalysis approach to climate change adaptation is on enhancing local knowledge of climate change and creating opportunities for coping with it. Katalysis aims at helping rural people to creatively manage their own resources in response to the growing threat of climate change. Katalysis builds on Farmer Field Schools ‘discovery learning’ tradition and other flexible, knowledge based approaches for improving agriculture through farmer participation in group problem-solving. The approach requires strong facilitators with flexible programmes and funding to support open-ended learning-action. Donor and development agencies must hand over more trust and responsibility to communities to design and implement their own agendas. Local people and outsiders need to be free to learn from each other, and to learn as they go along

A computer-controlled four-roll mill for investigations of particle and drop dynamics in two-dimensional linear shear flows

In this paper we describe the design and operating characteristics of a computer-controlled four-roll mill for investigations of particle and drop dynamics in two-dimensional linear flows. The control system is based upon the use of: a video camera to visualize the instantaneous position of the drop or particle; a PDP 11/23 computer, with a pipeline processor acting as an interface between the camera and computer, to calculate the position and implement a control strategy, and d.c. stepping motors to convert an electronic signal to angular velocities of the four rollers. The control objective is to keep the centre of mass of the drop/particle at the centre of the region between the rollers where there is a stagnation point in the undisturbed flow, while maintaining the shear-rate and the ratio of vorticity to strain rate in the flow at fixed values. The resulting system is suitable for studies of: the rotational motions of single solid particles; the deformation and burst of single droplets; or the hydrodynamic interactions of two particles or drops, one of which is held with its centre-of-mass fixed at the stagnation point of the undisturbed flow. In all cases, the flow can be varied from pure rotation to pure strain, and the shear rate can be either steady or changing as a prescribed function of time

Meteorology and Cimatology: On-Line Weather Studies

Through the Virginia Earth Science Collaborative (VESC), a partnership of nine institutes of higher education, non-profit organizations, and eighty-three school divisions, a 3-credit, graduate-level meteorology course was offered six times between Spring 2006 and Fall 2007. The course, entitled Meteorology, was offered at three locations (Richmond, Abingdon, and Harrisonburg), and a local instructor facilitated each section. Funding for the course development, instructor stipends, and participant expenses (including travel, meals, and tuition) was provided through a competitive Mathematics and Science Partnership (MSP) grant funded through the federal No Child Left Behind legislation of 2001. The framework of the course was the American Meteorological Society\u27s Online Weather Studies program, which provides meteorological content and laboratory investigations, and relies heavily on the use of Internet-accessed, real-time weather data to teach meteorological topics in a distance learning format. The 115 teacher participants were required to complete text readings and written assignments, conduct laboratory investigations, design projects using real—time meteorological data, complete exams, and attend three face-to-face meetings. For the purpose of the VESC grant evaluation, pre-test and post-test data were collected on 110 of the participants which indicated an average 14.7% increase in participants‘ content knowledge and use of real-time meteorological products (weather maps, satellite images, station models, etc.) in their instructional delivery

Written evidence to the House of Commons Business and Skills Committee (ed) Local enterprise partnerships and the Regional Growth Fund

The Business, Innovation and Skills Committee announced an inquiry looking into the Local Enterprise Partnerships and the Regional Growth Fund. In particular, the Committee examined how the proposed new structures would work, alongside issues such as distribution of funding, value for money, accountability, timing, transitional arrangements and required legislation. A Report on the Local Enterprise Partnerships was published on 26 April 2013

Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype

Abstract Background Recent studies have indicated the presence of multipotent mesenchymal stromal cells (MSCs) in human lung diseases. Excess airway smooth muscle, myofibroblasts and activated fibroblasts have each been noted in asthma, suggesting that mesenchymal progenitor cells play a role in asthma pathogenesis. We therefore sought to determine whether MSCs are present in the lungs of ovalbumin (OVA)-sensitized and challenged mice, a model of allergic airways disease. Methods Balb/c mice were sensitized and challenged with PBS or OVA over a 25 day period. Flow cytometry as well as colony forming and differentiation potential were used to analyze the emergence of MSCs along with gene expression studies using immunochemical analyses, quantitative polymerase chain reaction (qPCR), and gene expression beadchips. Results A CD45-negative subset of cells expressed Stro-1, Sca-1, CD73 and CD105. Selection for these markers and negative selection against CD45 yielded a population of cells capable of adipogenic, osteogenic and chondrogenic differentiation. Lungs from OVA-treated mice demonstrated a greater average colony forming unit-fibroblast (CFU-F) than control mice. Sorted cells differed from unsorted lung adherent cells, exhibiting a pattern of gene expression nearly identical to bone marrow-derived sorted cells. Finally, cells isolated from the bronchoalveolar lavage of a human asthma patient showed identical patterns of cell surface markers and differentiation potential. Conclusions In summary, allergen sensitization and challenge is accompanied by an increase of MSCs resident in the lungs that may regulate inflammatory and fibrotic responses.http://deepblue.lib.umich.edu/bitstream/2027.42/78265/1/1465-9921-11-127.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78265/2/1465-9921-11-127.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78265/3/1465-9921-11-127-S1.DOCPeer Reviewe

Workshop - Amundsen Sea Embayment Tectonic and Glacial History - Programme and Abstracts

Overall Objective: Review existing data and identify priorities for future geoscience research (terrestrial, marine and airborne) in the Amundsen Sea embayment (ASE) region required to develop a better understanding of the past, present and future behaviour of this sector of the West Antarctic Ice Sheet (WAIS). Background: The ASE is the most rapidly changing sector of the WAIS and contains enough ice to raise global sea level by 1.2 m. Over the past few years considerable efforts have been made to acquire new data to improve knowledge of the geological structure, subglacial topography, continental shelf bathymetry and glacial history of this remote region. In this workshop we aim to review the current state of knowledge on the tectonic and glacial evolution of the Amundsen Sea embayment. Particular emphasis will be placed on work that will improve boundary conditions for ice sheet models (e.g. subglacial topography, shelf bathymetry, palaeotopography, heat flow and substrate types) and provide palaeo-data against which model outputs can be compared. There will also be a focus on plans and targets for future scientific drilling that will reveal the history of this sector of the WAIS and its sensitivity to major climate changes