311 research outputs found

    Hit-Run Murders: Examination of the Body

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    Hit-Run Murders: Examination of the Body

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    Hit-Run Murders: Examination of the Body

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    What makes it so hard to look and to listen? Exploring the use of the Cognitive and Affective Supervisory Approach with children’s social work managers

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    This paper reports on the findings of an ESRC-funded Knowledge Exchange project designed to explore the contribution of an innovative approach to supervision to social work practitioners’ assessment and decision-making practices. The Cognitive and Affective Supervisory Approach (CASA) is informed by cognitive interviewing techniques originally designed to elicit best evidence from witnesses and victims of crime. Adapted here for use in childcare social work supervision contexts, this model is designed to enhance the quantity and quality of information available for decision-making. Facilitating the reporting of both ‘event information’ and ‘emotion information’, it allows a more detailed picture to emerge of events, as recalled by the individual involved, and the meaning they give to them. Practice supervisors from Children’s Services in two local authorities undertook to introduce the CASA into supervision sessions and were supported in this through the provision of regular reflective group discussions. The project findings highlight the challenges for practitioners of ‘detailed looking’ and for supervisors of ‘active listening’. The paper concludes by acknowledging that the CASA’s successful contribution to decision-making is contingent on both the motivation and confidence of supervisors to develop their skills and an organisational commitment to, and resourcing of, reflective supervisory practices and spaces

    Determination of single and competitive binary absorption isotherms for R and S optical isomers of fluoxetine

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    The pharmaceutical industry has come to rely on isotherm data when working with preparative chromatography. The data derived during isotherm measurement is used to optimize experimental conditions which will be used in the making of drugs. For the R- and S- enantiomers of Fluoxetine, four different methods were used to determine the single component isotherms and this data was fitted to the Langmuir Isotherm Model. Both enantiomers, when tested singly, fit the model using the Frontal Analysis Method and Retention Time Method, but did not fit the model when using the FACP and ECP methods. The major objective of this research was to determine whether the single component isotherm measurement can be used to predict the multi-component isotherm in order to avoid the cumbersome, tedious and very time consuming procedures for measuring the multi-component isotherm. Prediction of a multi-component isotherm using single component isotherms is in most cases impossible due to the competition between the two solutes and the difference in column saturation capacity of the two compounds. The two components of a chiral compound have very similar physical properties and therefore they should have similar column saturation capacities. The competitive binary isotherm was determined on the racemic mixture of Fluoxetine using the Frontal Analysis Method for Multi-Component Isotherms. It was then compared to values predicted from the Single Component studies and it was determined that the Multi-Component isotherm could be predicted from data obtained from the isotherms of the single components
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