1 research outputs found
Synthesis of Novel Nucleoside Analogues Built on a Bicyclo[4.1.0]heptane Scaffold
A new
class of carbocyclic nucleoside analogues built on a bicyclo[4.1.0]Āheptane
scaffold, a perspective novel pseudosugar pattern, have been conceived
as anti-HSV agents on the basis of initial proteināligand docking
studies. The asymmetric synthesis of a series of these compounds incorporating
different nucleobases has been efficiently completed starting from
1,4-cyclohexanedione